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mexiletine and Extrasystole, Ventricular

mexiletine has been researched along with Extrasystole, Ventricular in 10 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Research Excerpts

ExcerptRelevanceReference
"To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias."9.14Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010)
"To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias."5.14Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010)
"Significant differences between pre- and posttreatment number of VPC, severity of arrhythmia, HR variables, or occurrence of syncope were not observed in dogs treated with atenolol or procainamide."5.10Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. ( Atkins, CE; DeFrancesco, TC; Gordon, SG; Hamlin, RL; Keene, BW; Meurs, KM; Miller, MW; Moise, NS; Spier, AW; Wright, NA, 2002)
"60 cases of frequent ventricular extrasystole were randomly divided into two groups: a treatment group, and a control group."2.71Frequent ventricular extrasystole treated by needling neiguan (PC 6) plus oral administration of mexiletine--a report of 30 cases. ( Xu, W; Zhang, J, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's6 (60.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanders, RA1
Kurosawa, TA1
Gelzer, AR1
Kraus, MS1
Rishniw, M1
Hemsley, SA1
Moïse, NS2
Meurs, KM1
Spier, AW1
Wright, NA1
Atkins, CE1
DeFrancesco, TC1
Gordon, SG1
Hamlin, RL1
Keene, BW1
Miller, MW1
Takeuchi, T1
Sato, N1
Kawamura, Y1
Takahashi, F1
Sato, M1
Kikuchi, K1
Akasaka, N1
Go, K1
Fujimoto, K1
Hasebe, N1
Zhang, J1
Xu, W1
Shiraishi, H1
Hyogo, M1
Ishibashi, K1
Urao, N1
Tsukamoto, M1
Keira, N1
Hirasaki, S1
Shirayama, T1
Nakagawa, M1
Matsubara, H1
Yamauchi, M1
Watanabe, E1
Yasui, K1
Takeuchi, H1
Terasawa, T1
Sawada, K1
Hishida, H1
Kodama, I1
Garcia-Touchard, A1
Somers, VK1
Kara, T1
Nykodym, J1
Shamsuzzaman, A1
Lanfranchi, P1
Ackerman, MJ1
Mondillo, S1
Faglia, S1
D'Aprile, N1
Mangiacotti, L1
Campolo, MA1
Agricola, E1
Palazzuoli, V1
Golikov, AP1
Botolova, EN1
Rudnev, DV1

Trials

4 trials available for mexiletine and Extrasystole, Ventricular

ArticleYear
Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2010, Volume: 12, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cross-Over Studies; Dog Diseases; Dogs; Drug

2010
Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.
    Journal of the American Veterinary Medical Association, 2002, Aug-15, Volume: 221, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Dog Diseases; Dogs; Drug Therapy, C

2002
Frequent ventricular extrasystole treated by needling neiguan (PC 6) plus oral administration of mexiletine--a report of 30 cases.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2004, Volume: 24, Issue:1

    Topics: Acupuncture Points; Acupuncture Therapy; Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhyth

2004
[Therapy of arrhythmia induced by myocardial ischemia. Association of L-carnitine, propafenone and mexiletine].
    La Clinica terapeutica, 1995, Volume: 146, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Carnitine; Drug Sy

1995

Other Studies

6 other studies available for mexiletine and Extrasystole, Ventricular

ArticleYear
ECG of the month. Ventricular arrhythmia in a dog.
    Journal of the American Veterinary Medical Association, 2013, Aug-01, Volume: 243, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Dog Diseases; Dogs; Electrocardiography; Fatal Outcome; Female; Mex

2013
A case of a short-coupled variant of torsades de Pointes with electrical storm.
    Pacing and clinical electrophysiology : PACE, 2003, Volume: 26, Issue:2 Pt 1

    Topics: Electrocardiography; Electrophysiologic Techniques, Cardiac; Humans; Male; Mexiletine; Middle Aged;

2003
Rate-dependent QRS prolongation during exercise testing associated with hyperkalemia.
    Journal of electrocardiology, 2004, Volume: 37, Issue:3

    Topics: Aged; Anti-Arrhythmia Agents; Electrocardiography; Exercise Test; Heart Rate; Humans; Hyperkalemia;

2004
Prevention of ventricular extrasystole by mexiletine in patients with normal QT intervals is associated with a reduction of transmural dispersion of repolarization.
    International journal of cardiology, 2005, Aug-03, Volume: 103, Issue:1

    Topics: Action Potentials; Administration, Oral; Aged; Anti-Arrhythmia Agents; Electrocardiography, Ambulato

2005
Ventricular ectopy during REM sleep: implications for nocturnal sudden cardiac death.
    Nature clinical practice. Cardiovascular medicine, 2007, Volume: 4, Issue:5

    Topics: Adolescent; Anti-Arrhythmia Agents; Biopsy; Death, Sudden, Cardiac; Diagnosis, Differential; Echocar

2007
[Effectiveness of mexitil-depot in patients with chronic ventricular arrhythmia].
    Klinicheskaia meditsina, 1995, Volume: 73, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Chronic Disease; Delayed-Action Preparations; Elect

1995