mexiletine has been researched along with Drop Attack in 8 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Erythromycin is a selective IKr-blocking, action potential duration (APD)-prolonging drug, which may induce early afterdepolarizations (EADs) and torsade de pointes ventricular tachycardia." | 7.70 | Suppression of erythromycin-induced early afterdepolarizations and torsade de pointes ventricular tachycardia by mexiletine. ( Fazekas, T; Krassói, I; Lengyel, C; Papp, JG; Varró, A, 1998) |
| "Significant differences between pre- and posttreatment number of VPC, severity of arrhythmia, HR variables, or occurrence of syncope were not observed in dogs treated with atenolol or procainamide." | 5.10 | Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. ( Atkins, CE; DeFrancesco, TC; Gordon, SG; Hamlin, RL; Keene, BW; Meurs, KM; Miller, MW; Moise, NS; Spier, AW; Wright, NA, 2002) |
| "Erythromycin is a selective IKr-blocking, action potential duration (APD)-prolonging drug, which may induce early afterdepolarizations (EADs) and torsade de pointes ventricular tachycardia." | 3.70 | Suppression of erythromycin-induced early afterdepolarizations and torsade de pointes ventricular tachycardia by mexiletine. ( Fazekas, T; Krassói, I; Lengyel, C; Papp, JG; Varró, A, 1998) |
| "In 5 Mexiletine was added, shortening QTc and obtaining the disappearance of the T-wave alternance (TWA) in 3/3." | 1.91 | Autosomal Recessive Long QT Syndrome: Clinical Aspects and Therapy. ( Baban, A; Di Mambro, C; Drago, F; Gnazzo, M; Novelli, A; Paglia, S; Porco, L; Righi, D; Silvetti, MS; Tozzi, AE, 2023) |
| "Mexiletine is a Class 1B antiarrhythmic drug that causes the disappearance of T-wave alternans by shortening QTc and peak-to-end of the T wave." | 1.48 | A case report: Is mexiletine usage effective in the shortening of QTC interval and improving the T-wave alternans in Timothy syndrome? ( Ergul, Y; Tunca Sahin, G, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Righi, D | 1 |
| Porco, L | 1 |
| Di Mambro, C | 1 |
| Gnazzo, M | 1 |
| Baban, A | 1 |
| Paglia, S | 1 |
| Silvetti, MS | 1 |
| Novelli, A | 1 |
| Tozzi, AE | 1 |
| Drago, F | 1 |
| Tunca Sahin, G | 1 |
| Ergul, Y | 1 |
| Park, J | 1 |
| Kim, SK | 1 |
| Pak, HN | 1 |
| Meurs, KM | 1 |
| Spier, AW | 1 |
| Wright, NA | 1 |
| Atkins, CE | 1 |
| DeFrancesco, TC | 1 |
| Gordon, SG | 1 |
| Hamlin, RL | 1 |
| Keene, BW | 1 |
| Miller, MW | 1 |
| Moise, NS | 1 |
| Priori, SG | 1 |
| Napolitano, C | 1 |
| Paganini, V | 1 |
| Cantù, F | 1 |
| Schwartz, PJ | 1 |
| Hirata, K | 1 |
| Takagi, Y | 1 |
| Nakada, M | 1 |
| Kyushima, M | 1 |
| Asato, H | 1 |
| Fazekas, T | 1 |
| Krassói, I | 1 |
| Lengyel, C | 1 |
| Varró, A | 1 |
| Papp, JG | 1 |
| Rosenheck, S | 1 |
| Schmaltz, S | 1 |
| Kadish, AH | 1 |
| Summitt, J | 1 |
| Morady, F | 1 |
1 review available for mexiletine and Drop Attack
| Article | Year |
|---|---|
Molecular biology of the long QT syndrome: impact on management.
Topics: Action Potentials; Adrenergic Antagonists; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artifici | 1997 |
1 trial available for mexiletine and Drop Attack
| Article | Year |
|---|---|
Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Dog Diseases; Dogs; Drug Therapy, C | 2002 |
6 other studies available for mexiletine and Drop Attack
| Article | Year |
|---|---|
Autosomal Recessive Long QT Syndrome: Clinical Aspects and Therapy.
Topics: Child; Deafness; Heart Arrest; Humans; Jervell-Lange Nielsen Syndrome; KCNQ1 Potassium Channel; Long | 2023 |
A case report: Is mexiletine usage effective in the shortening of QTC interval and improving the T-wave alternans in Timothy syndrome?
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autistic Disorder; Child, Preschool; Electrocardiograp | 2018 |
A case of Long QT syndrome type 3 aggravated by beta-blockers and alleviated by mexiletine: the role of epinephrine provocation test.
Topics: Adolescent; Adrenergic beta-Antagonists; Defibrillators, Implantable; Diagnosis, Differential; Diagn | 2013 |
Beat-to-beat variation of the ST segment in a patient with right bundle branch block, persistent ST segment elevation, and ventricular fibrillation: a case report.
Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Electric Countershock; Electrocardiography; Hear | 1998 |
Suppression of erythromycin-induced early afterdepolarizations and torsade de pointes ventricular tachycardia by mexiletine.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Dogs; Electric Stimulatio | 1998 |
The effect of quinidine and mexiletine on the adaptation of ventricular refractoriness to an increase in rate.
Topics: Adaptation, Physiological; Adult; Aged; Drug Evaluation; Electrophysiology; Female; Heart; Heart Rat | 1991 |