mexiletine has been researched along with Disease Exacerbation in 1 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the safety and tolerability of mexiletine in a phase II double-blind randomized controlled trial of sporadic amyotrophic lateral sclerosis (SALS)." | 9.22 | A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression. ( Atassi, N; Barohn, RJ; Brown, RH; Cudkowicz, ME; Distad, JB; Graves, M; Greenblatt, DJ; Knox, AS; Macklin, EA; Parziale, N; Pestronk, A; Quinn, C; Salameh, JS; Shefner, JM; Simmons, Z; Swenson, A; Trivedi, J; Weiss, MD, 2016) |
| "To determine the safety and tolerability of mexiletine in a phase II double-blind randomized controlled trial of sporadic amyotrophic lateral sclerosis (SALS)." | 5.22 | A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression. ( Atassi, N; Barohn, RJ; Brown, RH; Cudkowicz, ME; Distad, JB; Graves, M; Greenblatt, DJ; Knox, AS; Macklin, EA; Parziale, N; Pestronk, A; Quinn, C; Salameh, JS; Shefner, JM; Simmons, Z; Swenson, A; Trivedi, J; Weiss, MD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiss, MD | 1 |
| Macklin, EA | 1 |
| Simmons, Z | 1 |
| Knox, AS | 1 |
| Greenblatt, DJ | 1 |
| Atassi, N | 1 |
| Graves, M | 1 |
| Parziale, N | 1 |
| Salameh, JS | 1 |
| Quinn, C | 1 |
| Brown, RH | 1 |
| Distad, JB | 1 |
| Trivedi, J | 1 |
| Shefner, JM | 1 |
| Barohn, RJ | 1 |
| Pestronk, A | 1 |
| Swenson, A | 1 |
| Cudkowicz, ME | 1 |
1 trial available for mexiletine and Disease Exacerbation
| Article | Year |
|---|---|
A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression.
Topics: Amyotrophic Lateral Sclerosis; Disease Progression; Dose-Response Relationship, Drug; Female; Follow | 2016 |