mexiletine has been researched along with Cardiomyopathy, Congestive in 14 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia." | 7.76 | A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010) |
| "The long-term effect of mexiletine on left ventricular (LV) contractility in patients with congestive heart failure is not clear." | 7.69 | Chronic effect of oral mexiletine administration on left ventricular contractility in patients with congestive heart failure: a study based on mitral regurgitant flow velocity measured by continuous-wave Doppler echocardiography. ( Hirabayashi, K; Matsuo, H; Morita, H; Nozaki, S; Ohmori, K; Yoshikawa, K, 1995) |
| " He had taken mexiletine for 5 months, as he had been diagnosed with dilated cardiomyopathy and ventricular arrhythmia." | 3.76 | A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia. ( Kim, SH; Kim, TH; Lee, SP; Park, SS; Shin, DH; Sohn, JW; Yoon, HJ, 2010) |
| "The long-term effect of mexiletine on left ventricular (LV) contractility in patients with congestive heart failure is not clear." | 3.69 | Chronic effect of oral mexiletine administration on left ventricular contractility in patients with congestive heart failure: a study based on mitral regurgitant flow velocity measured by continuous-wave Doppler echocardiography. ( Hirabayashi, K; Matsuo, H; Morita, H; Nozaki, S; Ohmori, K; Yoshikawa, K, 1995) |
| "Ranolazine is a drug that exerts antianginal and antiischemic effects and also acts as an antiarrhythmic in isolation and in combination with other class III medications." | 1.37 | Ranolazine reduces ventricular tachycardia burden and ICD shocks in patients with drug-refractory ICD shocks. ( Anderson, JL; Bair, TL; Bunch, TJ; Crandall, BG; Day, JD; Lappe, DL; Mader, KM; Mahapatra, S; May, HT; Molden, J; Muhlestein, JB; Murdock, D; Osborn, JS; Weiss, JP, 2011) |
| "Mexiletine clearance in patients with dilated cardiomyopathy (DCM) was decreased when compared with other diagnoses (Non-DCM)." | 1.31 | Evaluation of mexiletine clearance in a Japanese population. ( Kamakura, S; Komamura, K; Matsumoto, K; Miyatake, K; Shibakawa, M; Tamamura, A; Ueno, K, 2002) |
| "Mexiletine is a frequently used antiarrhythmic drug in patients with an implantable cardioverter defibrillator, usually thought of as producing no or minimal effects on the defibrillation threshold." | 1.31 | Mexiletine related chronic defibrillation threshold elevation: case report and review of the literature. ( Crystal, E; Ilia, R; Katz, A; Ovsyshcher, IE; Wagshal, AB, 2002) |
| "Our objective was to elucidate the mechanism of pharmacokinetic interaction between lidocaine and mexiletine, because an unexpected increase in plasma lidocaine concentration accompanied by severe side effects was observed when mexiletine was administered to a patient with dilated cardiomyopathy." | 1.31 | Possible mechanism for pharmacokinetic interaction between lidocaine and mexiletine. ( Fukuzawa, M; Funakoshi, S; Kugaya, Y; Maeda, Y; Murakami, T; Nakamura, M; Takano, M; Tsukiai, S; Yamasaki, M, 2002) |
| "Treatment with aprindine or mexiletine was effective in 7 (50%) of the 14 patients who did not respond to procainamide and/or disopyramide." | 1.28 | Analysis of ventricular arrhythmias in patients with dilated cardiomyopathy--relationship between the effects of antiarrhythmic agents and severity of myocardial lesions. ( Fukuzaki, H; Takarada, A; Yokota, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SP | 1 |
| Kim, SH | 1 |
| Kim, TH | 1 |
| Sohn, JW | 1 |
| Shin, DH | 1 |
| Park, SS | 1 |
| Yoon, HJ | 1 |
| Bunch, TJ | 1 |
| Mahapatra, S | 1 |
| Murdock, D | 1 |
| Molden, J | 1 |
| Weiss, JP | 1 |
| May, HT | 1 |
| Bair, TL | 1 |
| Mader, KM | 1 |
| Crandall, BG | 1 |
| Day, JD | 1 |
| Osborn, JS | 1 |
| Muhlestein, JB | 1 |
| Lappe, DL | 1 |
| Anderson, JL | 1 |
| Kolb, C | 1 |
| Lehmann, G | 1 |
| Schreieck, J | 1 |
| Ndrepepa, G | 1 |
| Schmitt, C | 1 |
| Morita, H | 1 |
| Hirabayashi, K | 1 |
| Nozaki, S | 1 |
| Ohmori, K | 1 |
| Yoshikawa, K | 1 |
| Matsuo, H | 1 |
| Schuster, MM | 1 |
| Manolis, AG | 1 |
| Katsivas, AG | 1 |
| Vassilopoulos, C | 1 |
| Tsatiris, CG | 1 |
| Ueno, K | 1 |
| Tamamura, A | 1 |
| Matsumoto, K | 1 |
| Komamura, K | 1 |
| Kamakura, S | 1 |
| Miyatake, K | 1 |
| Shibakawa, M | 1 |
| Crystal, E | 1 |
| Ovsyshcher, IE | 1 |
| Wagshal, AB | 1 |
| Katz, A | 1 |
| Ilia, R | 1 |
| Maeda, Y | 1 |
| Funakoshi, S | 1 |
| Nakamura, M | 1 |
| Fukuzawa, M | 1 |
| Kugaya, Y | 1 |
| Yamasaki, M | 1 |
| Tsukiai, S | 1 |
| Murakami, T | 1 |
| Takano, M | 1 |
| Brakhmann, I | 1 |
| Shmitt, K | 1 |
| Baĭer, T | 1 |
| Valdeker, B | 1 |
| Khilbel, T | 1 |
| Kiubler, V | 1 |
| Geraets, DR | 1 |
| Scott, SD | 1 |
| Ballew, KA | 1 |
| Tanabe, T | 1 |
| Takahashi, K | 1 |
| Yoshioka, K | 1 |
| Goto, Y | 1 |
| Takarada, A | 1 |
| Yokota, Y | 1 |
| Fukuzaki, H | 1 |
| Rae, AP | 1 |
| Spielman, SR | 1 |
| Kutalek, SP | 1 |
| Kay, HR | 1 |
| Horowitz, LN | 1 |
2 trials available for mexiletine and Cardiomyopathy, Congestive
| Article | Year |
|---|---|
Evaluation of disopyramide and mexiletine used alone and in combination for ventricular arrhythmias in patients with and without overt heart disease.
Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Cardiomyopathy, Dilated; Cardiomyop | 1991 |
Electrophysiologic assessment of antiarrhythmic drug efficacy for ventricular tachyarrhythmias associated with dilated cardiomyopathy.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated | 1987 |
12 other studies available for mexiletine and Cardiomyopathy, Congestive
| Article | Year |
|---|---|
A case of mexiletine-induced hypersensitivity syndrome presenting as eosinophilic pneumonia.
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Drug Hyper | 2010 |
Ranolazine reduces ventricular tachycardia burden and ICD shocks in patients with drug-refractory ICD shocks.
Topics: Acetanilides; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Cohort Studies; Def | 2011 |
Storms of ventricular tachyarrhythmias associated with primary hyperparathyroidism in a patient with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Bisoprolol; Cardiomyopathy, Dilated; Def | 2003 |
Chronic effect of oral mexiletine administration on left ventricular contractility in patients with congestive heart failure: a study based on mitral regurgitant flow velocity measured by continuous-wave Doppler echocardiography.
Topics: Administration, Oral; Adult; Aged; Blood Flow Velocity; Cardiomyopathy, Dilated; Echocardiography, D | 1995 |
Management of incessant ventricular tachycardia in a 39-year-old woman with cardiomyopathy.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Critical Illness; Defibrillators | 1997 |
Electrical storms in an ICD-recipient with 429 delivered appropriate shocks: therapeutic management with antiarrhythmic drug combination.
Topics: Aged; Amiodarone; Cardiomyopathy, Dilated; Defibrillators, Implantable; Electrocardiography; Follow- | 2002 |
Evaluation of mexiletine clearance in a Japanese population.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Cardiomyopathy, | 2002 |
Mexiletine related chronic defibrillation threshold elevation: case report and review of the literature.
Topics: Adult; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Equipment Failure; Heart Failure; Humans; Ma | 2002 |
Possible mechanism for pharmacokinetic interaction between lidocaine and mexiletine.
Topics: Aged; Aged, 80 and over; Animals; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Drug Interactions | 2002 |
[Anti-arrhythmia agents in heart failure].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; C | 1992 |
Toxicity potential of oral lidocaine in a patient receiving mexiletine.
Topics: Administration, Oral; Cardiomyopathy, Dilated; Central Nervous System; Female; Humans; Lidocaine; Me | 1992 |
Analysis of ventricular arrhythmias in patients with dilated cardiomyopathy--relationship between the effects of antiarrhythmic agents and severity of myocardial lesions.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Disop | 1990 |