Page last updated: 2024-10-31

mexiletine and Cardiomyopathies

mexiletine has been researched along with Cardiomyopathies in 7 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
" Many of these therapies are older medications being given new roles such as mexiletine for Brugada syndrome and diflunisal for transthyretin amyloid cardiomyopathy."4.95Therapeutic Strategies Targeting Inherited Cardiomyopathies. ( Tang, WHW; Varian, K, 2017)
" Sustained rapid ventricular tachyarrhythmias requiring cardioversion for termination were induced by double right ventricular apical extrastimuli during control, and treatment with disopyramide, quinidine, and fluocortolone."3.67Failure of corticosteroid therapy to prevent induction of ventricular tachycardia in sarcoidosis. ( Belhassen, B; Laniado, S; Pines, A, 1989)
"Monomorphic sustained ventricular tachycardia (MSVT) was revisited in relation to the electrophysiologic findings and their relation to the drug efficacy."2.40Reentrant ventricular tachycardia. Interpretations of electrophysiologic findings and its applications. ( Aizawa, Y; Tanabe, Y; Yamaura, M, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Varian, K1
Tang, WHW1
Gao, D1
Van Herendael, H1
Alshengeiti, L1
Dorian, P1
Mangat, I1
Korley, V1
Ahmad, K1
Golovchiner, G1
Aves, T1
Pinter, A1
Christie, JM1
Valdes, C1
Markowsky, SJ1
Aizawa, Y1
Tanabe, Y1
Yamaura, M1
Hokamura, Y1
Shono, H1
Uchida, H1
Kimura, Y1
Takenaka, S1
Fukuda, K1
Shima, K1
Hamada, T1
Yoshimura, M1
Belhassen, B1
Pines, A1
Laniado, S1
Kasanuki, H1
Onishi, S1
Hirosawa, K1

Reviews

2 reviews available for mexiletine and Cardiomyopathies

ArticleYear
Therapeutic Strategies Targeting Inherited Cardiomyopathies.
    Current heart failure reports, 2017, Volume: 14, Issue:4

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiomyopathies; Diflunisal; Geneti

2017
Reentrant ventricular tachycardia. Interpretations of electrophysiologic findings and its applications.
    Japanese heart journal, 1998, Volume: 39, Issue:2

    Topics: Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiomyopathies; Disopyramide; Electrocardiogra

1998

Other Studies

5 other studies available for mexiletine and Cardiomyopathies

ArticleYear
Mexiletine as an adjunctive therapy to amiodarone reduces the frequency of ventricular tachyarrhythmia events in patients with an implantable defibrillator.
    Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Cohort Studies

2013
Neurotoxicity of lidocaine combined with mexiletine.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:6

    Topics: Administration, Oral; Cardiomyopathies; Drug Therapy, Combination; Humans; Injections, Intravenous;

1993
[A case of cardiac sarcoidosis with various electrocardiographic change].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:5

    Topics: Cardiomyopathies; Electrocardiography; Female; Humans; Lung Diseases; Mexiletine; Middle Aged; Pacem

1989
Failure of corticosteroid therapy to prevent induction of ventricular tachycardia in sarcoidosis.
    Chest, 1989, Volume: 95, Issue:4

    Topics: Adult; Amiodarone; Cardiac Pacing, Artificial; Cardiomyopathies; Disopyramide; Drug Therapy, Combina

1989
The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of paroxysmal tachycardias.
    Japanese circulation journal, 1985, Volume: 49, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chromatogra

1985