mexiletine has been researched along with Cardiac Conduction Defect in 7 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Cashman, JR | 2 |
| Ryan, D | 2 |
| McKeithan, WL | 2 |
| Okolotowicz, K | 2 |
| Gomez-Galeno, J | 2 |
| Johnson, M | 2 |
| Sampson, KJ | 3 |
| Kass, RS | 3 |
| Pezhouman, A | 1 |
| Karagueuzian, HS | 1 |
| Mercola, M | 2 |
| Shimizu, T | 1 |
| Kawai, S | 1 |
| Kawada, A | 1 |
| Wakamiya, T | 1 |
| Nakano, Y | 1 |
| Watanabe, S | 1 |
| Iwamoto, M | 1 |
| Nasilli, G | 1 |
| Yiangou, L | 1 |
| Palandri, C | 1 |
| Cerbai, E | 1 |
| Davis, RP | 1 |
| Verkerk, AO | 1 |
| Casini, S | 1 |
| Remme, CA | 1 |
| Hu, RM | 1 |
| Tester, DJ | 1 |
| Li, R | 1 |
| Sun, T | 1 |
| Peterson, BZ | 1 |
| Ackerman, MJ | 1 |
| Makielski, JC | 1 |
| Tan, BH | 1 |
| Iyer, V | 1 |
| Roman-Campos, D | 1 |
| Kang, G | 1 |
| Fishman, GI | 1 |
| Hameed, A | 1 |
7 other studies available for mexiletine and Cardiac Conduction Defect
| Article | Year |
|---|---|
Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Behavior, Animal; Cardiac Conduction System Dise | 2021 |
Combined mexiletine and flecainide for severe long QT syndrome type 3.
Topics: Anti-Arrhythmia Agents; Cardiac Conduction System Disease; Electrocardiography; Flecainide; Humans; | 2023 |
Beneficial effects of chronic mexiletine treatment in a human model of SCN5A overlap syndrome.
Topics: Action Potentials; Brugada Syndrome; Cardiac Conduction System Disease; Humans; Long QT Syndrome; Me | 2023 |
Human iPSC-derived cardiomyocytes and pyridyl-phenyl mexiletine analogs.
Topics: Cardiac Conduction System Disease; Dose-Response Relationship, Drug; Humans; Induced Pluripotent Ste | 2021 |
Mexiletine rescues a mixed biophysical phenotype of the cardiac sodium channel arising from the SCN5A mutation, N406K, found in LQT3 patients.
Topics: Anti-Arrhythmia Agents; Cardiac Conduction System Disease; Female; HEK293 Cells; Humans; Infant; Lon | 2018 |
Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Conduction System Disease; Heart | 2015 |
Did Mutation Type Affect the Efficacy of Mexiletine Observed in Patients With LQTS Type 3?
Topics: Anti-Arrhythmia Agents; Cardiac Conduction System Disease; Humans; Long QT Syndrome; Mexiletine; Mut | 2017 |