Page last updated: 2024-10-31

mexiletine and Cardiac Complex, Premature

mexiletine has been researched along with Cardiac Complex, Premature in 86 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Research Excerpts

ExcerptRelevanceReference
"Eighty two patients with ventricular extrasystole (VES) after myocardial infarction had been treated with antiarrhythmic drugs in the half (41 patients) with mexiletine (M) and in the half (41 patients) with other ones."9.07[Long-term mexiletine treatment of ventricular arrhythmia in patients after myocardial infarction]. ( Axenti, I; Drazkiewicz, U; Olszowy, Z; Petelenz, T, 1992)
"In a controlled randomized cross-over trial, 21 patients with coronary artery disease and frequent ventricular arrhythmias were studied to test the efficacy and tolerance of mexiletine 200 mg t."9.06[Anti-arrhythmia effectiveness and tolerance of retard in comparison with standard mexiletine]. ( Geibel, A; Hohnloser, S; Hust, M; Just, H; Meinertz, T; Zehender, M, 1987)
"In 12 patients with coronary artery disease, 11 of them with previous myocardial infarction, the antiarrhythmic effects of orally administered flecainide (F."9.05[Antiarrhythmic efficacy of mexiletine, propafenone and flecainide in ventricular premature beats. A comparative study in patients after myocardial infarction (author's transl)]. ( Fabry, E; Klempt, HW; Nayebagha, A, 1982)
"The antiarrhythmic effects of the sustained release form of mexiletine (Mexitil-Perlongets) were evaluated in a double-blind placebo trial in 630 patients with recent documented myocardial infarction."9.05International mexiletine and placebo antiarrhythmic coronary trial: I. Report on arrhythmia and other findings. Impact Research Group. ( , 1984)
"Twenty-four patients with ventricular arrhythmias were treated with oral mexiletine for periods of from one to 16 months (total 10."9.04Long-term treatment of ventricular arrhythmias with oral mexiletine. ( Julian, DG; Prescott, LF; Talbot, RG, 1976)
"Fifty-four patients with a symptomatic ventricular arrhythmia underwent two 24-hour electrocardiographic recordings, respectively before and after two to three weeks treatment with mexiletine, at a dose of 200 mg three times a day."7.67Effectiveness of mexiletine in ventricular arrhythmias. ( Chaudron, JM; Luwaert, RJ, 1985)
"We describe a case of acute myocardial infarction complicated by atrial and ventricular arrhythmias in which it was possible to verify the effectiveness of lidocaine, mexiletine and propafenone."7.67Lidocaine, mexiletine and propafenone in the treatment of arrhythmias complicating myocardial infarction. A case report. ( Aguglia, F; De Marzio, P; Gnecchi, M, 1985)
"We studied the antiarrhythmic effect of oral Mexiletine in 20 patients with stable high-frequency ventricular arrhythmias refractory to therapeutic doses of conventional antiarrhythmic therapy."7.66[Mexiletine in treatment of chronic ventricular refractary arrhythmias (author's transl)]. ( Affinito, V; Ansalone, G; Bellocci, F; Loperfido, F; Lucente, M; Santarelli, P; Scabbia, E; Zecchi, P, 1981)
"The anti-arrhythmic drug mexiletine caused an oesophageal ulcer, confirmed by endoscopy and biopsy, in a 72-year-old woman."7.66[Esophageal ulcer caused by mexiletine]. ( Rudolph, R; Seckfort, H; Seggewiss, H, 1983)
"Oral mexiletine was begun immediately after completion of the intravenous infusion at a dose of 10 mg/kg/24 hr in the 10 responders to intravenous therapy."6.66Conversion from intravenous to oral mexiletine in the acute management of repetitive ventricular arrhythmia. ( Frye, SJ; Greenspan, AM; Horowitz, LN; Lowenthal, DT; Spielman, SR; Yacone, LA, 1985)
"In Mexiletine treated group the following results have been obtained: 19 excellent (76%), 4 good (16%) and 2 ineffective (8%)."6.65[Comparative study of the anti-arrhythmic activity of mexiletine and lidocaine in ventricular hyperkinetic arrhythmias]. ( Bonatti, V; Botti, G; Favaro, L; Finardi, A; Rolli, A, 1981)
" However, the pharmacokinetic interaction between mexiletine and theophylline has not been clarified."5.28[The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma]. ( Hariya, Y; Hayakawa, H; Inafuku, M; Nagasawa, K; Nakahara, Y; Ohtsu, F; Suzuki, T; Yoshioka, Y, 1992)
"In four children the first signs of arrhythmias were seen a short time after viral infection."5.26[Mexiletine in the treatment of ventricular arrhythmias (author's transl)]. ( Schlemmer, M; Wimmer, M, 1982)
"Eighty two patients with ventricular extrasystole (VES) after myocardial infarction had been treated with antiarrhythmic drugs in the half (41 patients) with mexiletine (M) and in the half (41 patients) with other ones."5.07[Long-term mexiletine treatment of ventricular arrhythmia in patients after myocardial infarction]. ( Axenti, I; Drazkiewicz, U; Olszowy, Z; Petelenz, T, 1992)
"In a controlled randomized cross-over trial, 21 patients with coronary artery disease and frequent ventricular arrhythmias were studied to test the efficacy and tolerance of mexiletine 200 mg t."5.06[Anti-arrhythmia effectiveness and tolerance of retard in comparison with standard mexiletine]. ( Geibel, A; Hohnloser, S; Hust, M; Just, H; Meinertz, T; Zehender, M, 1987)
"In 12 patients with coronary artery disease, 11 of them with previous myocardial infarction, the antiarrhythmic effects of orally administered flecainide (F."5.05[Antiarrhythmic efficacy of mexiletine, propafenone and flecainide in ventricular premature beats. A comparative study in patients after myocardial infarction (author's transl)]. ( Fabry, E; Klempt, HW; Nayebagha, A, 1982)
"The antiarrhythmic effects of the sustained release form of mexiletine (Mexitil-Perlongets) were evaluated in a double-blind placebo trial in 630 patients with recent documented myocardial infarction."5.05International mexiletine and placebo antiarrhythmic coronary trial: I. Report on arrhythmia and other findings. Impact Research Group. ( , 1984)
"Twenty-four patients with ventricular arrhythmias were treated with oral mexiletine for periods of from one to 16 months (total 10."5.04Long-term treatment of ventricular arrhythmias with oral mexiletine. ( Julian, DG; Prescott, LF; Talbot, RG, 1976)
"Mexiletine is a type I antiarrhythmic drug that is structurally similar to lidocaine."3.76Mexiletine: a new type I antiarrhythmic agent. ( Bauman, JL; Schrader, BJ, 1986)
"The electrophysiological effects of combination therapy of mexiletine and propafenone were assessed using standard 12-lead electrocardiogram (standard ECG), signal-averaged ECG (SAECG), and ambulatory ECG in 31 patients with ventricular arrhythmias."3.68Mexiletine and propafenone: a comparative study of monotherapy, low, and full dose combination therapy. ( Haruna, M; Kato, H; Lee, S; Machii, T; Nonokawa, M; Takanaka, C; Yabe, S, 1992)
" In patients refractory to amiodarone alone or to a combination with mexiletine, the combined treatment with amiodarone and class-I-C drugs such as flecainide and encainide prolongs the cycle length of ventricular tachycardia, but does not suppress induction of ventricular tachycardia during programmed stimulation."3.68[Combination anti-arrhythmic drug therapy]. ( Jung, W; Lüderitz, B; Manz, M, 1992)
"Fifty-four patients with a symptomatic ventricular arrhythmia underwent two 24-hour electrocardiographic recordings, respectively before and after two to three weeks treatment with mexiletine, at a dose of 200 mg three times a day."3.67Effectiveness of mexiletine in ventricular arrhythmias. ( Chaudron, JM; Luwaert, RJ, 1985)
"We describe a case of acute myocardial infarction complicated by atrial and ventricular arrhythmias in which it was possible to verify the effectiveness of lidocaine, mexiletine and propafenone."3.67Lidocaine, mexiletine and propafenone in the treatment of arrhythmias complicating myocardial infarction. A case report. ( Aguglia, F; De Marzio, P; Gnecchi, M, 1985)
"We studied the antiarrhythmic effect of oral Mexiletine in 20 patients with stable high-frequency ventricular arrhythmias refractory to therapeutic doses of conventional antiarrhythmic therapy."3.66[Mexiletine in treatment of chronic ventricular refractary arrhythmias (author's transl)]. ( Affinito, V; Ansalone, G; Bellocci, F; Loperfido, F; Lucente, M; Santarelli, P; Scabbia, E; Zecchi, P, 1981)
"The anti-arrhythmic drug mexiletine caused an oesophageal ulcer, confirmed by endoscopy and biopsy, in a 72-year-old woman."3.66[Esophageal ulcer caused by mexiletine]. ( Rudolph, R; Seckfort, H; Seggewiss, H, 1983)
"Flecainide was superior to mexiletine in overall PVC reduction (p less than 0."2.67A double-blind crossover comparison of flecainide and slow-release mexiletine in the treatment of stable premature ventricular complexes. ( Balducelli, M; Boriani, G; Capucci, A; Carini, G; Carozzi, A; Di Pasquale, G; Finzi, A; Frabetti, L; Magnani, B; Pinelli, G, 1991)
" The study confirms that long-term use of mexiletine is efficacious and relatively free of cardiac depressant effects even in patients with diminished LV function."2.67Long-term effect of mexiletine on left ventricular function and relation to suppression of ventricular arrhythmia. ( Doherty, P; Eisenberg, B; Hughes, E; Klein, R; Shand, M; Singh, S, 1990)
"Disopyramide was effective in 50% of total cases with 44."2.67Mexiletine and disopyramide suppress ventricular premature contractions (VPC) irrespective of the relationship between the VPC and the underlying heart rate. ( Fujino, T; Hara, M; Ishida, S; Ito, M; Maeda, T; Nakagawa, M; Saikawa, T; Shimoyama, N; Takahashi, N; Yonemochi, H, 1992)
"Oral mexiletine was begun immediately after completion of the intravenous infusion at a dose of 10 mg/kg/24 hr in the 10 responders to intravenous therapy."2.66Conversion from intravenous to oral mexiletine in the acute management of repetitive ventricular arrhythmia. ( Frye, SJ; Greenspan, AM; Horowitz, LN; Lowenthal, DT; Spielman, SR; Yacone, LA, 1985)
" The most frequently used dosage of mexiletine during each 3-month treatment period was 600 mg/day (50."2.66Chronic mexiletine therapy for suppression of ventricular arrhythmias. ( Duke, M, 1988)
"In 16 healthy males bioavailability of Mexicord (Polfa) was studied, in comparison with mexiletine of foreign made."2.66[Comparative evaluation of biological availability and anti-arrhythmia effectiveness of Mexicard (mexiletine Polfa)]. ( Filipek, M; Koliński, P; Markiewicz, M; Nartowicz, E; Paczkowski, D; Sadowski, Z, 1989)
"Mexiletine was statistically more effective (P less than ."2.66Comparative study of mexiletine and quinidine in the treatment of ventricular ectopia. ( Assey, ME; Hanger, KH; Hudson, WM; Miller, SC, 1985)
"In Mexiletine treated group the following results have been obtained: 19 excellent (76%), 4 good (16%) and 2 ineffective (8%)."2.65[Comparative study of the anti-arrhythmic activity of mexiletine and lidocaine in ventricular hyperkinetic arrhythmias]. ( Bonatti, V; Botti, G; Favaro, L; Finardi, A; Rolli, A, 1981)
"Sustained ventricular tachyarrhythmias were induced in 12 of the 56 trials of the VSP."1.32Ventricular tachyarrhythmias in a canine model of LQT3: arrhythmogenic effects of sympathetic activity and therapeutic effects of mexiletine. ( Aizawa, Y; Chinushi, M; Hosaka, Y; Komura, S; Sugiura, H; Tagawa, M; Washizuka, T, 2003)
"When disopyramide or mexiletine were ineffective or not tolerated, the alternative drug was administered and the efficacy was again evaluated."1.28Efficacy of disopyramide and mexiletine used alone or in combination in the treatment of ventricular premature beats. ( Hiraoka, M; Motomiya, T; Sakurada, H, 1991)
"In 5 patients (71%) ventricular tachycardia was abolished."1.28Effect of the combination of low-dose mexiletine and metoprolol on ventricular arrhythmia. ( Graboys, TB; Lampert, S; Ravid, S, 1991)
"The antiarrhythmic effectiveness and safety of 12-h oral administration of mexiletine were evaluated in adult outpatients with a baseline hourly rate of PVCs of 30 or higher who had initially shown at least a 50 percent reduction of this rate when treated with mexiletine at an 8-h dosage interval."1.28Efficacy of oral mexiletine therapy at a 12-h dosage interval. ( Hughes, EM; MacGregor, TR; Sharon, G; Steen, SN, 1990)
" However, the pharmacokinetic interaction between mexiletine and theophylline has not been clarified."1.28[The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma]. ( Hariya, Y; Hayakawa, H; Inafuku, M; Nagasawa, K; Nakahara, Y; Ohtsu, F; Suzuki, T; Yoshioka, Y, 1992)
"Ventricular extrasystoles completely regressed after the initial rapid intravenous injection in 7 out of the 12 patients (58,3 p."1.26[Anti-arrhythmic effects of mexiletine]. ( Besse, P; Favreau, L; Ledain, L; Page, A, 1982)
"In four children the first signs of arrhythmias were seen a short time after viral infection."1.26[Mexiletine in the treatment of ventricular arrhythmias (author's transl)]. ( Schlemmer, M; Wimmer, M, 1982)
" In 26 of the 32 patients optimum dosage for maximum beneficial effect appeared to be 200 mg 3 times daily."1.26[Treatment of rhythm disorders of ventricular origin with KO 1173 (Mexiletin) (author's transl)]. ( Esser, H; Kikis, D, 1977)
"In 9 cases, the ventricular premature beats were totally or almost totally abolished up to 20 to 100 min."1.26The efficacy of intravenous mexiletine on ventricular ectopic activity. ( Kulbertus, HE; Waleffe, A, 1977)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199061 (70.93)18.7374
1990's23 (26.74)18.2507
2000's2 (2.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chinushi, M1
Tagawa, M1
Sugiura, H1
Komura, S1
Hosaka, Y1
Washizuka, T1
Aizawa, Y1
Tian, XL1
Cheng, Y1
Zhang, T1
Liao, ML1
Yong, SL1
Wang, QK1
Theisen, K1
Jahrmärker, H1
Rozenshtraukh, LV1
Aniukhovskiĭ, EP1
Beloshapko, GG1
Dremin, SA1
Kipshidze, NN1
Chapidze, GE1
Dzhandzhgava, ShM1
Ol'binskaia, LI1
Iurina, MS1
Litvitskiĭ, PF1
Sandrikov, VA1
Kulikova, AG1
Smirnova, OV1
Sgammini, H1
Evequoz, C1
Vera, T1
Cengarle, S1
Chuit, R1
Kuschnir, E1
Codecà, L1
Gruppillo, P1
Padovan, GC1
Masoni, C1
Masoni, A1
Rolli, A1
Bonatti, V1
Finardi, A1
Favaro, L1
Botti, G1
Bellocci, F1
Ansalone, G1
Scabbia, E1
Santarelli, P1
Lucente, M1
Affinito, V1
Loperfido, F1
Zecchi, P1
Kurbanov, RD1
Mazur, NA7
Zacà, F1
Cremonesi, A1
Pagliarani, PL1
Guelfi, P1
Bugiardini, R1
Lasagna, I1
Ghinelli, M1
Luciani, G1
Mehta, J1
Conti, CR1
Schlemmer, M1
Wimmer, M1
Klempt, HW1
Nayebagha, A1
Fabry, E1
Ledain, L1
Page, A1
Favreau, L1
Besse, P1
Petelenz, T2
Chruściel, TL1
Gaszewska, I1
Słomińska-Petelenz, T1
Elertowicz, M1
Grzybek, B1
Lüderitz, B3
Rudolph, R1
Seggewiss, H1
Seckfort, H1
Richard, M1
Touminet, MA1
Revillon, L1
Pacholke, H1
Beck, OA1
Hochrein, H1
Masotti, G2
Morettini, A1
Casolo, GC1
Ieri, A2
Zipoli, A1
Serneri, GG1
Arakawa, K1
Doi, Y1
Hashiba, K1
Mitsuoka, T1
Yanaga, T1
Hata, Y1
Ogawa, N1
Cernusková, L1
Benes, L1
Csöllei, J1
Tumová, I1
Svec, P1
Zaliunas, R1
Zabiela, P1
Slapikas, R1
Vainoras, A1
Pentiokiniene, D1
Levisauskiene, R1
Bechtold, H1
Meyer, U1
Komori, S1
Sano, S1
Li, BH1
Matsumura, K1
Naitoh, A1
Mochizuki, S1
Ishihara, T2
Watanabe, A1
Umetani, K1
Ijiri, H1
Mondillo, S1
Faglia, S1
D'Aprile, N1
Mangiacotti, L1
Campolo, MA1
Agricola, E1
Palazzuoli, V1
Talbot, RG1
Julian, DG1
Prescott, LF1
Pozenel, H1
Campbell, NP1
Chaturvedi, NC1
Shanks, RG1
Kelly, JG1
Strong, JE1
Adgey, AA1
Kühn, P1
Kroiss, A1
Klicpera, M1
Zilcher, H1
Kaindl, F2
Esser, H1
Kikis, D1
Waleffe, A1
Kulbertus, HE1
Merx, W1
Henning, B1
Brunner, H1
De Bakker, JM1
Härtel, H1
Stauch, M1
Sigel, H1
Steinbach, K1
Glogar, D1
Weber, H1
Kinast, H1
Joskowicz, G1
Loskot, F1
Bauer, U1
Liakishev, AA1
Podrid, FD1
Piotrovskiĭ, VK1
Takanaka, C1
Nonokawa, M1
Machii, T1
Lee, S1
Kato, H1
Haruna, M1
Yabe, S1
Lombardi, F1
Torzillo, D1
Sandrone, G1
Dalla Vecchia, L1
Cappiello, E1
Habot, B1
Rabinovitz, C1
Friedensohn, A1
Schlesinger, Z1
Baumel, Y1
Saikawa, T1
Nakagawa, M1
Takahashi, N1
Ishida, S1
Fujino, T1
Ito, M1
Shimoyama, N1
Hara, M1
Yonemochi, H1
Maeda, T1
Jung, W1
Manz, M2
Inafuku, M1
Suzuki, T1
Ohtsu, F1
Hariya, Y1
Nagasawa, K1
Yoshioka, Y1
Nakahara, Y1
Hayakawa, H1
Drazkiewicz, U1
Axenti, I1
Olszowy, Z1
Urumbaev, RK1
Suprunova, IP1
Imanakunova, DSh1
Rakhimova, GR1
Steen, SN1
Hughes, EM1
Sharon, G1
MacGregor, TR1
Ueno, K1
Miyai, K1
Seki, T1
Kawaguchi, Y1
Singh, S1
Klein, R1
Eisenberg, B1
Hughes, E1
Shand, M1
Doherty, P1
Zang, Y1
Korkushko, OV2
Shatilo, VB1
Capucci, A1
Di Pasquale, G1
Boriani, G1
Carini, G1
Balducelli, M1
Frabetti, L1
Carozzi, A1
Finzi, A1
Pinelli, G1
Magnani, B1
Abdalla, A5
Nazarenko, VA1
Sakurada, H1
Motomiya, T1
Hiraoka, M1
Fujimoto, Y1
Fukuki, M1
Hirokane, Y1
Kotake, H1
Mashiba, H1
Tanabe, T2
Takahashi, K1
Yoshioka, K1
Goto, Y2
Ravid, S1
Lampert, S1
Graboys, TB2
Horowitz, LN1
Greenspan, AM1
Spielman, SR1
Frye, SJ1
Yacone, LA1
Lowenthal, DT1
Accettura, D2
De Toma, L2
Lagioia, R2
Mastropasqua, F2
Mangini, SG2
Scrutinio, D2
Rizzon, P2
Vitale, P1
Agretto, A1
Iarussi, D1
Perna, B1
Romano, A1
Casale, D1
Porreca, GP1
Chaudron, JM1
Luwaert, RJ1
Podrid, PJ1
Schrader, BJ1
Bauman, JL1
Butenko, AG1
Di Taranto, A1
De Matteis, D1
Wagner, WL1
Zehender, M1
Geibel, A1
Hust, M1
Hohnloser, S1
Meinertz, T1
Just, H1
Caiati, C1
Carlone, S1
Delfino, M1
Angelici, E1
Teneggi, V1
Del Bolgia, F1
Serra, P1
Duke, M1
Hattori, Y1
Hidaka, T1
Aisaka, K1
Satoh, F1
Breithaupt, H1
Schmidt, A1
Patt, MV1
Grossbard, CL1
Lown, B1
Sumarokov, AB1
Iavorskaia, NV1
Murakawa, Y1
Toda, I1
Nozaki, A1
Kawakubo, K1
Sugimoto, T1
Poggesi, L1
Scarti, L1
Lanzetta, T1
Grazzini, M1
Del Bene, P1
Masini, G1
Del Citerna, F1
Carnovali, M1
Orlov, VN1
Shpektor, AV1
Mamaev, VI1
Susliak, NN1
Sadowski, Z1
Paczkowski, D1
Markiewicz, M1
Nartowicz, E1
Koliński, P1
Filipek, M1
Aguglia, F1
Gnecchi, M1
De Marzio, P1
Yoshikawa, H1
Tagawa, R1
Furuya, H1
Ide, M1
Assey, ME1
Hudson, WM1
Hanger, KH1
Miller, SC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter Defibrillator (CALYPSO) PILOT TRIAL[NCT01576042]27 participants (Actual)Interventional2012-05-31Terminated (stopped due to Main objectives of the study were met; consensus among investigators that continuing the study would not add new information beyond that already learned.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cardiovascular Hospitalizations

Records participants hospitalized for VT during the study (NCT01576042)
Timeframe: Baseline, 6 months

Interventionparticipants (Number)
Catheter Ablation5
Antiarrhythmic Medication7

Number of Participants Completed Month 3 Follow-Up

Records participants who completed Month 3 Follow-Up Visit (NCT01576042)
Timeframe: 3 months

Interventionparticipants (Number)
Catheter Ablation11
Antiarrhythmic Medication12

Number of Participants Completed Month 6 Follow-Up

Records participants who completed Month 6 Follow-Up Visit (NCT01576042)
Timeframe: 6 Months

Interventionparticipants (Number)
Catheter Ablation7
Antiarrhythmic Medication10

Number of Participants Had at Least One of the Efficacy Outcome Measurement

Records participants who had at least one of the efficacy outcome measurement (including death, hospitalization due to VT) (NCT01576042)
Timeframe: 6 Months

Interventionparticipants (Number)
Catheter Ablation11
Antiarrhythmic Medication14

Number of Participants Received Treatment Assigned

Records participants who received study randomized treatment during the study (NCT01576042)
Timeframe: 6 months

Interventionparticipants (Number)
Catheter Ablation11
Antiarrhythmic Medication14

Number of Participants Remained on Randomized Treatment Assignment

Records participants who only received study treatment as randomized during the entire study (NCT01576042)
Timeframe: 6 month

Interventionparticipants (Number)
Catheter Ablation6
Antiarrhythmic Medication13

Number of Participants Switched to Other Arm

Records participants who received study treatment as randomized and later switched to other treatment arm during the study (NCT01576042)
Timeframe: 6 months

Interventionparticipants (Number)
Catheter Ablation5
Antiarrhythmic Medication1

Time to First Recurrent ICD Therapy for VT

Days from the date of the first study treatment to the date of first ICD recurrent therapy for VT. (NCT01576042)
Timeframe: Baseline, 6 months

InterventionDays (Mean)
Catheter Ablation70.1
Antiarrhythmic Medication78.7

Reviews

3 reviews available for mexiletine and Cardiac Complex, Premature

ArticleYear
[Medical treatment of extrasystole and tachycardia (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1980, Jan-18, Volume: 122, Issue:3

    Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardi

1980
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
    Cardiovascular clinics, 1985, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple

1985
Mexiletine: a new type I antiarrhythmic agent.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Biotransformation; Cardiac Complexes, Premature; Clinical Trials as

1986

Trials

37 trials available for mexiletine and Cardiac Complex, Premature

ArticleYear
[Clinical study of the anti-arrhythmia preparation, mexitil].
    Kardiologiia, 1980, Volume: 20, Issue:10

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Tr

1980
[Comparative study of the anti-arrhythmic activity of mexiletine and lidocaine in ventricular hyperkinetic arrhythmias].
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Female; Heart Ventricles; Humans; Lidocain

1981
[Comparative effectiveness of ethmozine, mexitil, quinidine and obsidan in the treatment of ventricular rhythm disorders].
    Kardiologiia, 1981, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; H

1981
Mexiletine, a new antiarrhythmic agent, for treatment of premature ventricular complexes.
    The American journal of cardiology, 1982, Feb-01, Volume: 49, Issue:2

    Topics: Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Diarrhea; Double

1982
[Antiarrhythmic efficacy of mexiletine, propafenone and flecainide in ventricular premature beats. A comparative study in patients after myocardial infarction (author's transl)].
    Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:5

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Coronary Disease; Electrocardiogr

1982
[Potentiation of an anti-arrhythmia action by the combined use of mexiletine and propranolol].
    Deutsche medizinische Wochenschrift (1946), 1984, Mar-02, Volume: 109, Issue:9

    Topics: Aged; Cardiac Complexes, Premature; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Elec

1984
Efficacy of mexiletine in the medium-term treatment of ventricular arrhythmias. A randomized, double-blind, crossover trial against placebo in ambulatory patients.
    The Journal of international medical research, 1984, Volume: 12, Issue:2

    Topics: Adult; Aged; Ambulatory Care; Blood Pressure; Cardiac Complexes, Premature; Clinical Trials as Topic

1984
International mexiletine and placebo antiarrhythmic coronary trial: I. Report on arrhythmia and other findings. Impact Research Group.
    Journal of the American College of Cardiology, 1984, Volume: 4, Issue:6

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Delayed-A

1984
Signal-averaged ECG in prediction of the short-term suppression of ventricular premature beats by Mexiletine.
    International journal of cardiology, 1994, Volume: 46, Issue:3

    Topics: Administration, Oral; Algorithms; Cardiac Complexes, Premature; Delayed-Action Preparations; Electro

1994
[Therapy of arrhythmia induced by myocardial ischemia. Association of L-carnitine, propafenone and mexiletine].
    La Clinica terapeutica, 1995, Volume: 146, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Carnitine; Drug Sy

1995
Long-term treatment of ventricular arrhythmias with oral mexiletine.
    American heart journal, 1976, Volume: 91, Issue:1

    Topics: Administration, Oral; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as T

1976
[Anti-arrhythmia action of mexiletine (KO 1173) on ventricular ectopic arrhythmias in dependence of its serum concentration].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Cardiac Complexes, Premature; Clinical Trials as Topic; Coronary Disease; Drug Evaluation; Female; H

1977
[The effect of mexiletine in comparison to placebo on extrasystole at rest and under strain].
    Advances in clinical pharmacology, 1978, Volume: 16

    Topics: Adult; Aged; Cardiac Complexes, Premature; Clinical Trials as Topic; Electrocardiography; Female; Hu

1978
[Clinical value of computer-assisted arrhythmia analysis].
    Advances in clinical pharmacology, 1978, Volume: 16

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Computers

1978
[Treatment of ventricular extrasystole with mexiletine and Neo-gilurytmal in myocardial infarct patients].
    Advances in clinical pharmacology, 1978, Volume: 16

    Topics: Adult; Aged; Ajmaline; Cardiac Complexes, Premature; Clinical Trials as Topic; Electrocardiography;

1978
Mexiletine and disopyramide suppress ventricular premature contractions (VPC) irrespective of the relationship between the VPC and the underlying heart rate.
    Japanese heart journal, 1992, Volume: 33, Issue:5

    Topics: Cardiac Complexes, Premature; Disopyramide; Electrocardiography, Ambulatory; Female; Heart Rate; Hum

1992
[Long-term mexiletine treatment of ventricular arrhythmia in patients after myocardial infarction].
    Polskie Archiwum Medycyny Wewnetrznej, 1992, Volume: 87, Issue:3

    Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Dose-Response Relationship, Drug; F

1992
[Use of an anti-arrhythmia drug mexicord in the treatment of ventricular extrasystole].
    Kardiologiia, 1992, Volume: 32, Issue:3

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Female; Heart Ventricles; Humans;

1992
Long-term effect of mexiletine on left ventricular function and relation to suppression of ventricular arrhythmia.
    The American journal of cardiology, 1990, Nov-15, Volume: 66, Issue:17

    Topics: Aged; Cardiac Complexes, Premature; Electrocardiography, Ambulatory; Exercise Test; Humans; Male; Me

1990
[Comparison of the anti-arrhythmic effectiveness of ethacizine, ethmozine, cordarone, mexitil and ritmilen in elderly patients with ventricular extrasystole].
    Kardiologiia, 1990, Volume: 30, Issue:11

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Heart Ventricl

1990
A double-blind crossover comparison of flecainide and slow-release mexiletine in the treatment of stable premature ventricular complexes.
    International journal of clinical pharmacology research, 1991, Volume: 11, Issue:1

    Topics: Cardiac Complexes, Premature; Delayed-Action Preparations; Double-Blind Method; Electrocardiography;

1991
[Comparative effectiveness of class I anti-arrhythmia drugs and the algorithms of their selection in patients with ventricular arrhythmia].
    Kardiologiia, 1991, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Heart Conduct

1991
Evaluation of disopyramide and mexiletine used alone and in combination for ventricular arrhythmias in patients with and without overt heart disease.
    International journal of cardiology, 1991, Volume: 32, Issue:3

    Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Cardiomyopathy, Dilated; Cardiomyop

1991
Conversion from intravenous to oral mexiletine in the acute management of repetitive ventricular arrhythmia.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:6

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Tria

1985
[Comparison of mexiletine and dihydroquinidine in the treatment of ventricular asystolic arrhythmia].
    Cardiologia (Rome, Italy), 1985, Volume: 30, Issue:2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Asthenia; Cardiac Complexes, Premature; Clinical Trials as Topic;

1985
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
    Cardiovascular clinics, 1985, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Comple

1985
Mexiletine: a new type I antiarrhythmic agent.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Biotransformation; Cardiac Complexes, Premature; Clinical Trials as

1986
[Clinical study of the effectiveness and characteristics of the action of mexitil in the treatment of extrasystole in middle-aged and elderly patients].
    Kardiologiia, 1986, Volume: 26, Issue:4

    Topics: Age Factors; Aged; Cardiac Complexes, Premature; Clinical Trials as Topic; Dose-Response Relationshi

1986
[Combination of sotalol with the class I B substances mexiletine or tocainide in complex ventricular extrasystole].
    Zeitschrift fur Kardiologie, 1987, Volume: 76, Issue:5

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Therapy, Combination; Electr

1987
[Anti-arrhythmia effectiveness and tolerance of retard in comparison with standard mexiletine].
    Zeitschrift fur Kardiologie, 1987, Volume: 76, Issue:8

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Coronary

1987
Chronic mexiletine therapy for suppression of ventricular arrhythmias.
    Clinical cardiology, 1988, Volume: 11, Issue:3

    Topics: Cardiac Complexes, Premature; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electrocar

1988
[Experience in using anti-arrhythmia preparations of groups I and III in patients with arrhythmia resistant to therapy].
    Kardiologiia, 1988, Volume: 28, Issue:3

    Topics: Aconitine; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; Dr

1988
[Comparative study of the effectiveness of allapinin in patients with frequent and stable extrasystole].
    Kardiologiia, 1988, Volume: 28, Issue:11

    Topics: Aconitine; Aconitum; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Tri

1988
Efficacy of mexiletine in chronic ventricular arrhythmias: a multicentre double-blind medium-term trial.
    International journal of clinical pharmacology research, 1989, Volume: 9, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Chronic Disease;

1989
[Comparative effectiveness of Na+ channel blockers in ventricular disorders of cardiac rhythm].
    Kardiologiia, 1989, Volume: 29, Issue:8

    Topics: Adult; Aged; Calcium Channel Blockers; Cardiac Complexes, Premature; Clinical Trials as Topic; Disop

1989
[Comparative evaluation of biological availability and anti-arrhythmia effectiveness of Mexicard (mexiletine Polfa)].
    Kardiologia polska, 1989, Volume: 32, Issue:5

    Topics: Adult; Aged; Biological Availability; Cardiac Complexes, Premature; Clinical Trials as Topic; Double

1989
Comparative study of mexiletine and quinidine in the treatment of ventricular ectopia.
    Southern medical journal, 1985, Volume: 78, Issue:5

    Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Clinical Trials as Topic; Double-Bl

1985

Other Studies

48 other studies available for mexiletine and Cardiac Complex, Premature

ArticleYear
Ventricular tachyarrhythmias in a canine model of LQT3: arrhythmogenic effects of sympathetic activity and therapeutic effects of mexiletine.
    Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Dogs; Electrocardiography; Heart Rate

2003
Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S.
    Biochemical and biophysical research communications, 2007, Jan-26, Volume: 352, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Asparagine; Cardiac Complexes, Premature; Long QT Syndrome; Mexiletin

2007
[Decrease in the fast sodium inflow current, a possible reason for the anti-arrhythmic action of etmozin and mexityl in the late stage of experimental myocardial infarct].
    Kardiologiia, 1980, Volume: 20, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Dogs; Dose-Response Relationship, Dru

1980
[Antiarrhythmic effect and influence on myocardial contractile function of the preparation, mexitil].
    Kardiologiia, 1980, Volume: 20, Issue:12

    Topics: Adult; Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Evaluation; Drug Evaluation

1980
[Use of mexitil in ventricular arrhythmias].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:4

    Topics: Adult; Aged; Cardiac Complexes, Premature; Female; Humans; Male; Mexiletine; Middle Aged; Propylamin

1981
[Prolonged treatment with oral mexiletine in severe ventricular extrasystole].
    Arquivos brasileiros de cardiologia, 1981, Volume: 36, Issue:1

    Topics: Adult; Aged; Cardiac Complexes, Premature; Chagas Cardiomyopathy; Female; Humans; Male; Mexiletine;

1981
[Oral maintenance treatment with mexiletine after acute administration of xilocaine (author's transl)].
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:4

    Topics: Administration, Oral; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Female; Humans; Injections

1981
[Mexiletine in treatment of chronic ventricular refractary arrhythmias (author's transl)].
    Giornale italiano di cardiologia, 1981, Volume: 11, Issue:4

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Female; Heart Ventricles; Humans; M

1981
[Effectiveness of mexiletine in arrhythmia of effort].
    Minerva cardioangiologica, 1981, Volume: 29, Issue:11

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Evaluati

1981
[Mexiletine in the treatment of ventricular arrhythmias (author's transl)].
    Padiatrie und Padologie, 1982, Volume: 17, Issue:2

    Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Child; Female; Heart Ventricles; Humans; Mexilet

1982
[Anti-arrhythmic effects of mexiletine].
    Archives des maladies du coeur et des vaisseaux, 1982, Volume: 75, Issue:5

    Topics: Administration, Oral; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Electrocardiography;

1982
[Mexiletine in the treatment of arrhythmia].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Aug-23, Volume: 37, Issue:29-30

    Topics: Adolescent; Adult; Aged; Cardiac Complexes, Premature; Chemical Phenomena; Chemistry; Female; Follow

1982
[Drug therapy of arrhythmia in coronary cardiopathy].
    La Clinica terapeutica, 1983, Apr-15, Volume: 105, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Comp

1983
[Esophageal ulcer caused by mexiletine].
    Deutsche medizinische Wochenschrift (1946), 1983, Jul-01, Volume: 108, Issue:26

    Topics: Aged; Cardiac Complexes, Premature; Esophageal Diseases; Female; Hemoptysis; Humans; Male; Mexiletin

1983
[Injectable mexiletine and disorders of the auricular rhythm].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:7

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atrial Flutter; Cardiac Complexes, Premature; Female; Heart Atria

1983
Well-controlled comparative study of the clinical effectiveness of intravenous mexiletine and procainamide on ventricular premature contraction.
    Japanese heart journal, 1984, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiac Complexes, Premature; Electrocardiography; Female;

1984
Carbamate analogues of tocainide.
    Die Pharmazie, 1994, Volume: 49, Issue:9

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Carbamates; C

1994
Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide.
    Heart and vessels, 1995, Volume: 10, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Complexes, Premature; Coronary Disease; Dis

1995
Haemodynamic studies on mexiletine, anew antiarrhythmic agent.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 1

    Topics: Cardiac Complexes, Premature; Female; Heart; Hemodynamics; Humans; Male; Mexiletine; Middle Aged; Pr

1977
The development of mexiletine in the management of ventricular dysrhythmias.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 1

    Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Female; Heart Ventricles; Humans; Male; Mexileti

1977
Antiarrhythmic and haemodynamic effects of mexiletine.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 1

    Topics: Adult; Blood Pressure; Cardiac Complexes, Premature; Cardiac Output; Female; Heart Ventricles; Hemod

1977
[Treatment of rhythm disorders of ventricular origin with KO 1173 (Mexiletin) (author's transl)].
    Medizinische Klinik, 1977, Sep-02, Volume: 72, Issue:35

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Female; Human

1977
The efficacy of intravenous mexiletine on ventricular ectopic activity.
    Acta cardiologica, 1977, Volume: 32, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Evaluation; Female; Heart Ventricles;

1977
[Clinical study of the antiarrhythmic action of Mexityl in ventricular disorders of the cardiac rhythm].
    Kardiologiia, 1979, Volume: 19, Issue:10

    Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Evaluation;

1979
Mexiletine and propafenone: a comparative study of monotherapy, low, and full dose combination therapy.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:11 Pt 2

    Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography;

1992
Autonomic effects of antiarrhythmic drugs and their importance.
    European heart journal, 1992, Volume: 13 Suppl F

    Topics: Adult; Autonomic Nervous System; Cardiac Complexes, Premature; Electrocardiography; Female; Flecaini

1992
[A severe skin reaction following mexiletene].
    Harefuah, 1992, Dec-01, Volume: 123, Issue:11

    Topics: Aged; Cardiac Complexes, Premature; Drug Eruptions; Humans; Male; Mexiletine

1992
[Combination anti-arrhythmic drug therapy].
    Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Therapy, Combination; Electro

1992
[The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma].
    Journal of cardiology, 1992, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Asthma; Cardiac Complexes, Premature; Drug Interactions; Female; Humans; Ma

1992
Efficacy of oral mexiletine therapy at a 12-h dosage interval.
    Chest, 1990, Volume: 97, Issue:2

    Topics: Administration, Oral; Aged; Cardiac Complexes, Premature; Drug Administration Schedule; Electrocardi

1990
Interaction between theophylline and mexiletine.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:5

    Topics: Aged; Asthma; Cardiac Complexes, Premature; Drug Interactions; Heart Block; Humans; Male; Mexiletine

1990
[Evaluation of risks and treatment of asymptomatic ventricular arrhythmias].
    Zhonghua xin xue guan bing za zhi, 1990, Volume: 18, Issue:4

    Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Electrocardiography, Ambulatory; Female;

1990
Efficacy of disopyramide and mexiletine used alone or in combination in the treatment of ventricular premature beats.
    Cardiovascular drugs and therapy, 1991, Volume: 5 Suppl 4

    Topics: Adult; Aged; Cardiac Complexes, Premature; Disopyramide; Dose-Response Relationship, Drug; Drug Admi

1991
Clinical study on coupling interval of ventricular premature contraction in patients with organic heart disease.
    Japanese circulation journal, 1991, Volume: 55, Issue:12

    Topics: Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography, Ambulatory; Femal

1991
Effect of the combination of low-dose mexiletine and metoprolol on ventricular arrhythmia.
    Clinical cardiology, 1991, Volume: 14, Issue:12

    Topics: Aged; Cardiac Complexes, Premature; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ele

1991
[Mexiletine in the acute treatment of ventricular arrhythmias in cardiosurgery].
    Minerva cardioangiologica, 1985, Volume: 33, Issue:12

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiac Surgical Procedures; Female

1985
Effectiveness of mexiletine in ventricular arrhythmias.
    Acta cardiologica, 1985, Volume: 40, Issue:6

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Electrocardiography; Female; Heart

1985
[Evaluation of the efficiency of mexiletine in ventricular extrasystole in the post-infarct stage].
    La Clinica terapeutica, 1987, Mar-31, Volume: 120, Issue:6

    Topics: Adult; Aged; Cardiac Complexes, Premature; Drug Administration Schedule; Female; Humans; Male; Mexil

1987
[Evaluation of delayed-action preparations of mexiletine and dihydroquinidine in the treatment of ventricular extrasystolic arrhythmia].
    Cardiologia (Rome, Italy), 1987, Volume: 32, Issue:9

    Topics: Aged; Cardiac Complexes, Premature; Delayed-Action Preparations; Double-Blind Method; Female; Heart

1987
[Therapeutic efficacy of mexiletine].
    Recenti progressi in medicina, 1987, Volume: 78, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Cardiac Complexes, Premature; Female; Humans; Male; Mexiletine; Midd

1987
Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Disopyramide; Guin

1988
[Treatment with mexiletine. Clinical and pharmacokinetic studies].
    Klinische Wochenschrift, 1988, Jun-01, Volume: 66, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Cardiac Complexes, Premature; Electrocardiography; Humans; Infusions

1988
[The effectiveness of a combination of mexitil with etmozin, allapinin or quinidine in ventricular extrasystole].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:5

    Topics: Aconitine; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Evaluation; Drug Therap

1988
[Experience with the combined use of 1st- and 2d-group anti-arrhythmic preparations in patients with refractory arrhythmia].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:6

    Topics: Aconitine; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug E

1988
Combination antiarrhythmic therapy for management of malignant ventricular arrhythmia.
    The American journal of cardiology, 1988, Nov-03, Volume: 62, Issue:14

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Drug Therapy, Combinatio

1988
Effects of antiarrhythmic drugs on the repetitive extrasystole threshold and the ventricular fibrillation threshold.
    Cardiology, 1989, Volume: 76, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Disopyram

1989
Lidocaine, mexiletine and propafenone in the treatment of arrhythmias complicating myocardial infarction. A case report.
    International journal of cardiology, 1985, Volume: 7, Issue:3

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Dru

1985
Evaluation of antiarrhythmic drug efficacy using holter electrocardiographic technique.
    Japanese circulation journal, 1985, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes,

1985