Page last updated: 2024-10-31

mexiletine and Canine Diseases

mexiletine has been researched along with Canine Diseases in 3 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Research Excerpts

ExcerptRelevanceReference
"To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias."9.14Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010)
"To determine the spontaneous variability of ventricular arrhythmias (VA) and evaluate anti-arrhythmic efficacy of mexiletine, sotalol, and a mexiletine-sotalol combination in German shepherd dogs (GSD) with inherited arrhythmias."5.14Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study. ( Gelzer, AR; Hemsley, SA; Kraus, MS; Moïse, NS; Rishniw, M, 2010)
"Significant differences between pre- and posttreatment number of VPC, severity of arrhythmia, HR variables, or occurrence of syncope were not observed in dogs treated with atenolol or procainamide."5.10Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers. ( Atkins, CE; DeFrancesco, TC; Gordon, SG; Hamlin, RL; Keene, BW; Meurs, KM; Miller, MW; Moise, NS; Spier, AW; Wright, NA, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanders, RA1
Kurosawa, TA1
Gelzer, AR1
Kraus, MS1
Rishniw, M1
Hemsley, SA1
Moïse, NS2
Meurs, KM1
Spier, AW1
Wright, NA1
Atkins, CE1
DeFrancesco, TC1
Gordon, SG1
Hamlin, RL1
Keene, BW1
Miller, MW1

Trials

2 trials available for mexiletine and Canine Diseases

ArticleYear
Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2010, Volume: 12, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cross-Over Studies; Dog Diseases; Dogs; Drug

2010
Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.
    Journal of the American Veterinary Medical Association, 2002, Aug-15, Volume: 221, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Dog Diseases; Dogs; Drug Therapy, C

2002

Other Studies

1 other study available for mexiletine and Canine Diseases

ArticleYear
ECG of the month. Ventricular arrhythmia in a dog.
    Journal of the American Veterinary Medical Association, 2013, Aug-01, Volume: 243, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Dog Diseases; Dogs; Electrocardiography; Fatal Outcome; Female; Mex

2013