mexiletine has been researched along with Bulbo-Spinal Atrophy, X-Linked in 2 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Bulbo-Spinal Atrophy, X-Linked: An X-linked recessive form of spinal muscular atrophy. It is due to a mutation of the gene encoding the ANDROGEN RECEPTOR.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with spinal and bulbar muscular atrophy (SBMA) often experience muscular weakness under cold exposure." | 3.11 | Mexiletine in spinal and bulbar muscular atrophy: a randomized controlled trial. ( Hashizume, A; Hijikata, Y; Hirakawa, A; Inagaki, T; Ito, D; Katsuno, M; Kinoshita, F; Kishimoto, Y; Nakamura, T; Shimizu, S; Yamada, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, S | 2 |
| Hashizume, A | 2 |
| Hijikata, Y | 2 |
| Inagaki, T | 2 |
| Ito, D | 2 |
| Kishimoto, Y | 1 |
| Kinoshita, F | 2 |
| Hirakawa, A | 2 |
| Shimizu, S | 1 |
| Nakamura, T | 2 |
| Katsuno, M | 2 |
| Nakatochi, M | 1 |
| Kobayashi, Y | 1 |
2 trials available for mexiletine and Bulbo-Spinal Atrophy, X-Linked
| Article | Year |
|---|---|
Mexiletine in spinal and bulbar muscular atrophy: a randomized controlled trial.
Topics: Bulbo-Spinal Atrophy, X-Linked; Humans; Mexiletine; Muscle Weakness; Paresis; Pressure; Tongue | 2022 |
Study protocol for the MEXiletine hydrochloride administration trial: a placebo-controlled, randomised, double-blind, multicentre, crossover study of its efficacy and safety in spinal and bulbar muscular atrophy (MEXPRESS).
Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Bulbo-Spinal Atrophy, X-Linked; Cold Tem | 2018 |