mexiletine has been researched along with Brugada ECG Pattern in 4 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Many of these therapies are older medications being given new roles such as mexiletine for Brugada syndrome and diflunisal for transthyretin amyloid cardiomyopathy." | 4.95 | Therapeutic Strategies Targeting Inherited Cardiomyopathies. ( Tang, WHW; Varian, K, 2017) |
| "The SCN5A mutation, P1332L, is linked to a malignant form of congenital long QT syndrome, type 3 (LQT3), and affected patients are highly responsive to the Na+ channel blocking drug, mexiletine." | 3.88 | Complex interactions in a novel SCN5A compound mutation associated with long QT and Brugada syndrome: Implications for Na+ channel blocking pharmacotherapy for de novo conduction disease. ( Aschar-Sobbi, R; Backx, PH; Bayer, JD; Chauhan, VS; Gollob, M; Liu, J; Spears, D; Tsushima, R; Vigmond, EJ; Wauchop, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nasilli, G | 1 |
| Yiangou, L | 1 |
| Palandri, C | 1 |
| Cerbai, E | 1 |
| Davis, RP | 1 |
| Verkerk, AO | 1 |
| Casini, S | 1 |
| Remme, CA | 1 |
| Varian, K | 1 |
| Tang, WHW | 1 |
| Liu, J | 1 |
| Bayer, JD | 1 |
| Aschar-Sobbi, R | 1 |
| Wauchop, M | 1 |
| Spears, D | 1 |
| Gollob, M | 1 |
| Vigmond, EJ | 1 |
| Tsushima, R | 1 |
| Backx, PH | 1 |
| Chauhan, VS | 1 |
| Dolz-Gaitón, P | 1 |
| Núñez, M | 1 |
| Núñez, L | 1 |
| Barana, A | 1 |
| Amorós, I | 1 |
| Matamoros, M | 1 |
| Pérez-Hernández, M | 1 |
| González de la Fuente, M | 1 |
| Alvarez-López, M | 1 |
| Macías-Ruiz, R | 1 |
| Tercedor-Sánchez, L | 1 |
| Jiménez-Jáimez, J | 1 |
| Delpón, E | 1 |
| Caballero, R | 1 |
| Tamargo, J | 1 |
1 review available for mexiletine and Brugada ECG Pattern
| Article | Year |
|---|---|
Therapeutic Strategies Targeting Inherited Cardiomyopathies.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiomyopathies; Diflunisal; Geneti | 2017 |
3 other studies available for mexiletine and Brugada ECG Pattern
| Article | Year |
|---|---|
Beneficial effects of chronic mexiletine treatment in a human model of SCN5A overlap syndrome.
Topics: Action Potentials; Brugada Syndrome; Cardiac Conduction System Disease; Humans; Long QT Syndrome; Me | 2023 |
Complex interactions in a novel SCN5A compound mutation associated with long QT and Brugada syndrome: Implications for Na+ channel blocking pharmacotherapy for de novo conduction disease.
Topics: Animals; Brugada Syndrome; CHO Cells; Computer Simulation; Cricetulus; Humans; Long QT Syndrome; Mal | 2018 |
Functional characterization of a novel frameshift mutation in the C-terminus of the Nav1.5 channel underlying a Brugada syndrome with variable expression in a Spanish family.
Topics: Biological Transport; Brugada Syndrome; Female; Frameshift Mutation; Humans; Mexiletine; Middle Aged | 2013 |