mexiletine has been researched along with Brain Edema in 2 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The volume of cerebral infarction was measured in serial brain sections stained with triphenyltetrazolium chloride (TTC)." | 5.31 | Alteration of ischemic reperfusion injury in the rat neocortex by a potent antioxidant mexiletine. ( Chang, CZ; Howng, SL; Jeng, AY; Kung, SS; Kwan, AL; Loh, JK; Winardi, D, 2002) |
| "Rats treated with mexiletine, EGb 761, and mexiletine plus EGb 761 had significantly lower MDA levels than the control group (P<0." | 1.32 | Effects of mexiletine, ginkgo biloba extract (EGb 761), and their combination on experimental head injury. ( Akdemir, H; Koç, RK; Menkü, A; Narin, F; Saraymen, R; Tayfur, V, 2003) |
| "The volume of cerebral infarction was measured in serial brain sections stained with triphenyltetrazolium chloride (TTC)." | 1.31 | Alteration of ischemic reperfusion injury in the rat neocortex by a potent antioxidant mexiletine. ( Chang, CZ; Howng, SL; Jeng, AY; Kung, SS; Kwan, AL; Loh, JK; Winardi, D, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menkü, A | 1 |
| Koç, RK | 1 |
| Tayfur, V | 1 |
| Saraymen, R | 1 |
| Narin, F | 1 |
| Akdemir, H | 1 |
| Chang, CZ | 1 |
| Winardi, D | 1 |
| Loh, JK | 1 |
| Kung, SS | 1 |
| Howng, SL | 1 |
| Jeng, AY | 1 |
| Kwan, AL | 1 |
2 other studies available for mexiletine and Brain Edema
| Article | Year |
|---|---|
Effects of mexiletine, ginkgo biloba extract (EGb 761), and their combination on experimental head injury.
Topics: Animals; Brain Edema; Disease Models, Animal; Drug Therapy, Combination; Ginkgo biloba; Head Injurie | 2003 |
Alteration of ischemic reperfusion injury in the rat neocortex by a potent antioxidant mexiletine.
Topics: Animals; Anti-Arrhythmia Agents; Brain Edema; Brain Ischemia; Carotid Arteries; Cerebral Arteries; C | 2002 |