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mexiletine and Asthma

mexiletine has been researched along with Asthma in 4 studies

Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
" However, the pharmacokinetic interaction between mexiletine and theophylline has not been clarified."5.28[The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma]. ( Hariya, Y; Hayakawa, H; Inafuku, M; Nagasawa, K; Nakahara, Y; Ohtsu, F; Suzuki, T; Yoshioka, Y, 1992)
" However, the pharmacokinetic interaction between mexiletine and theophylline has not been clarified."1.28[The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma]. ( Hariya, Y; Hayakawa, H; Inafuku, M; Nagasawa, K; Nakahara, Y; Ohtsu, F; Suzuki, T; Yoshioka, Y, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Groeben, H1
Foster, WM1
Brown, RH1
Zemenick, RB1
Inafuku, M1
Suzuki, T1
Ohtsu, F1
Hariya, Y1
Nagasawa, K1
Yoshioka, Y1
Nakahara, Y1
Hayakawa, H1
Ueno, K1
Miyai, K1
Seki, T1
Kawaguchi, Y1

Trials

1 trial available for mexiletine and Asthma

ArticleYear
Intravenous lidocaine and oral mexiletine block reflex bronchoconstriction in asthmatic subjects.
    American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:4 Pt 1

    Topics: Adult; Anesthetics, Local; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Me

1996

Other Studies

3 other studies available for mexiletine and Asthma

ArticleYear
Lidocaine and oral mexiletine block reflex bronchoconstriction in asthmatic subjects.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:5

    Topics: Administration, Oral; Aerosols; Anesthetics, Local; Asthma; Bronchoconstriction; Humans; Injections,

1997
[The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma].
    Journal of cardiology, 1992, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Asthma; Cardiac Complexes, Premature; Drug Interactions; Female; Humans; Ma

1992
Interaction between theophylline and mexiletine.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:5

    Topics: Aged; Asthma; Cardiac Complexes, Premature; Drug Interactions; Heart Block; Humans; Male; Mexiletine

1990