mexiletine and Asthma
mexiletine has been researched along with Asthma in 4 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, the pharmacokinetic interaction between mexiletine and theophylline has not been clarified." | 5.28 | [The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma]. ( Hariya, Y; Hayakawa, H; Inafuku, M; Nagasawa, K; Nakahara, Y; Ohtsu, F; Suzuki, T; Yoshioka, Y, 1992) |
| " However, the pharmacokinetic interaction between mexiletine and theophylline has not been clarified." | 1.28 | [The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma]. ( Hariya, Y; Hayakawa, H; Inafuku, M; Nagasawa, K; Nakahara, Y; Ohtsu, F; Suzuki, T; Yoshioka, Y, 1992) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Groeben, H | 1 |
| Foster, WM | 1 |
| Brown, RH | 1 |
| Zemenick, RB | 1 |
| Inafuku, M | 1 |
| Suzuki, T | 1 |
| Ohtsu, F | 1 |
| Hariya, Y | 1 |
| Nagasawa, K | 1 |
| Yoshioka, Y | 1 |
| Nakahara, Y | 1 |
| Hayakawa, H | 1 |
| Ueno, K | 1 |
| Miyai, K | 1 |
| Seki, T | 1 |
| Kawaguchi, Y | 1 |
Trials
1 trial available for mexiletine and Asthma
| Article | Year |
|---|---|
Intravenous lidocaine and oral mexiletine block reflex bronchoconstriction in asthmatic subjects.
Topics: Adult; Anesthetics, Local; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Me | 1996 |
Other Studies
3 other studies available for mexiletine and Asthma
| Article | Year |
|---|---|
Lidocaine and oral mexiletine block reflex bronchoconstriction in asthmatic subjects.
Topics: Administration, Oral; Aerosols; Anesthetics, Local; Asthma; Bronchoconstriction; Humans; Injections, | 1997 |
[The effect of mexiletine on theophylline pharmacokinetics in patients with bronchial asthma].
Topics: Aged; Aged, 80 and over; Asthma; Cardiac Complexes, Premature; Drug Interactions; Female; Humans; Ma | 1992 |
Interaction between theophylline and mexiletine.
Topics: Aged; Asthma; Cardiac Complexes, Premature; Drug Interactions; Heart Block; Humans; Male; Mexiletine | 1990 |