mexiletine has been researched along with Anterior Choroidal Artery Infarction in 4 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The volume of cerebral infarction was measured in serial brain sections stained with triphenyltetrazolium chloride (TTC)." | 5.31 | Alteration of ischemic reperfusion injury in the rat neocortex by a potent antioxidant mexiletine. ( Chang, CZ; Howng, SL; Jeng, AY; Kung, SS; Kwan, AL; Loh, JK; Winardi, D, 2002) |
| "Furthermore, brain seizure activity recorded following 1 h MCAo and 72 h of recovery in injured rats was either completely blocked (30 min pre-MCAo treatment) or significantly reduced (30 min post-MCAo treatment) with RS100642 (1." | 5.31 | Neuroprotective effects of the sodium channel blocker RS100642 and attenuation of ischemia-induced brain seizures in the rat. ( Tortella, FC; Williams, AJ, 2002) |
| " Pretreatment with Mex resulted in a significant infarct volume reduction when administered intraperitoneally, either at the dosage of 50 or 60 mg/kg, 1 hr before MCA occlusion (P < 0." | 5.30 | Mexiletine and magnesium independently, but not combined, protect against permanent focal cerebral ischemia in Wistar rats. ( Ayoub, IA; Harris, FB; Hassan, M; Lee, EJ; Maynard, KI; Ogilvy, CS, 1999) |
| "Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness." | 5.28 | Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990) |
| "The volume of cerebral infarction was measured in serial brain sections stained with triphenyltetrazolium chloride (TTC)." | 1.31 | Alteration of ischemic reperfusion injury in the rat neocortex by a potent antioxidant mexiletine. ( Chang, CZ; Howng, SL; Jeng, AY; Kung, SS; Kwan, AL; Loh, JK; Winardi, D, 2002) |
| "Furthermore, brain seizure activity recorded following 1 h MCAo and 72 h of recovery in injured rats was either completely blocked (30 min pre-MCAo treatment) or significantly reduced (30 min post-MCAo treatment) with RS100642 (1." | 1.31 | Neuroprotective effects of the sodium channel blocker RS100642 and attenuation of ischemia-induced brain seizures in the rat. ( Tortella, FC; Williams, AJ, 2002) |
| " Pretreatment with Mex resulted in a significant infarct volume reduction when administered intraperitoneally, either at the dosage of 50 or 60 mg/kg, 1 hr before MCA occlusion (P < 0." | 1.30 | Mexiletine and magnesium independently, but not combined, protect against permanent focal cerebral ischemia in Wistar rats. ( Ayoub, IA; Harris, FB; Hassan, M; Lee, EJ; Maynard, KI; Ogilvy, CS, 1999) |
| "Mexiletine was generally well tolerated with only two patients experiencing transient nausea and dizziness." | 1.28 | Mexiletine for thalamic pain syndrome. ( Awerbuch, GI; Sandyk, R, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, EJ | 1 |
| Ayoub, IA | 1 |
| Harris, FB | 1 |
| Hassan, M | 1 |
| Ogilvy, CS | 1 |
| Maynard, KI | 1 |
| Chang, CZ | 1 |
| Winardi, D | 1 |
| Loh, JK | 1 |
| Kung, SS | 1 |
| Howng, SL | 1 |
| Jeng, AY | 1 |
| Kwan, AL | 1 |
| Williams, AJ | 1 |
| Tortella, FC | 1 |
| Awerbuch, GI | 1 |
| Sandyk, R | 1 |
4 other studies available for mexiletine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Mexiletine and magnesium independently, but not combined, protect against permanent focal cerebral ischemia in Wistar rats.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Drug Administration Schedule; Magnesium; Male; Mexilet | 1999 |
Alteration of ischemic reperfusion injury in the rat neocortex by a potent antioxidant mexiletine.
Topics: Animals; Anti-Arrhythmia Agents; Brain Edema; Brain Ischemia; Carotid Arteries; Cerebral Arteries; C | 2002 |
Neuroprotective effects of the sodium channel blocker RS100642 and attenuation of ischemia-induced brain seizures in the rat.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Dose-Response Relationship, Drug; Electroenceph | 2002 |
Mexiletine for thalamic pain syndrome.
Topics: Cerebral Hemorrhage; Cerebral Infarction; Female; Humans; Male; Mexiletine; Middle Aged; Multiple Sc | 1990 |