mexiletine has been researched along with Aging in 5 studies
Mexiletine: Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
mexiletine : An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mean values for elimination half-life and oral clearance were 12." | 1.28 | Pharmacokinetics of mexiletine in the elderly. ( Barbeau, G; Blouin, M; Fiset, C; Grech-Bélanger, O; Kishka, P; LeBoeuf, E, 1989) |
| "Mexiletine was applied extracellularly." | 1.27 | Sodium current in freshly isolated and in cultured single rat myocardial cells: frequency and voltage-dependent block by mexiletine. ( Bodewei, R; Hering, S; Wollenberger, A, 1983) |
| "The antipyrine half-life was 38." | 1.27 | Cirrhosis of the liver markedly impairs the elimination of mexiletine. ( Halinen, MO; Hietakorpi, S; Lampinen, LM; Pentikäinen, PJ, 1986) |
| "Mexiletine (50 mg) was administered orally three times daily for 10 days." | 1.27 | Effects of age on the pharmacokinetics of mexiletine. ( Carlier, J; Dressé, A; el Allaf, D, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brooke, MH | 1 |
| Hering, S | 1 |
| Bodewei, R | 1 |
| Wollenberger, A | 1 |
| Grech-Bélanger, O | 1 |
| Barbeau, G | 1 |
| Kishka, P | 1 |
| Fiset, C | 1 |
| LeBoeuf, E | 1 |
| Blouin, M | 1 |
| Pentikäinen, PJ | 1 |
| Hietakorpi, S | 1 |
| Halinen, MO | 1 |
| Lampinen, LM | 1 |
| el Allaf, D | 1 |
| Carlier, J | 1 |
| Dressé, A | 1 |
5 other studies available for mexiletine and Aging
| Article | Year |
|---|---|
Fiction: the Christmas card.
Topics: Activities of Daily Living; Adult; Aging; Anecdotes as Topic; Anti-Arrhythmia Agents; Humans; Male; | 2005 |
Sodium current in freshly isolated and in cultured single rat myocardial cells: frequency and voltage-dependent block by mexiletine.
Topics: Aging; Animals; Animals, Newborn; Biological Transport, Active; Mexiletine; Myocardium; Propylamines | 1983 |
Pharmacokinetics of mexiletine in the elderly.
Topics: Adult; Aged; Aging; Humans; Male; Mexiletine | 1989 |
Cirrhosis of the liver markedly impairs the elimination of mexiletine.
Topics: Adult; Aging; Antipyrine; Blood Proteins; Humans; Injections, Intravenous; Kinetics; Liver Cirrhosis | 1986 |
Effects of age on the pharmacokinetics of mexiletine.
Topics: Administration, Oral; Adult; Aged; Aging; Female; Humans; Kinetics; Male; Mexiletine; Middle Aged | 1986 |