mevastatin has been researched along with Leukemia, Myeloid in 4 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 3 (75.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Appelbaum, FR; Banker, DE; Li, HY; Willman, CL; Zager, RA | 1 |
Appelbaum, FR; Banker, DE; Stirewalt, DL; Willman, CL; Zager, RA | 1 |
Burke, LP; Lewis, LD; Perez, RP | 1 |
Hohl, RJ; Larson, RA; Mannickarottu, V; Yachnin, S | 1 |
4 other study(ies) available for mevastatin and Leukemia, Myeloid
Article | Year |
---|---|
Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses.
Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Cytarabine; Daunorubicin; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lipoproteins, LDL; Lovastatin; Membrane Lipids; Protein Prenylation; Protein Processing, Post-Translational; Radiation-Sensitizing Agents; Tricarboxylic Acids; Tumor Cells, Cultured | 2003 |
Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Case-Control Studies; Cell Survival; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lovastatin; Mutation; Myeloid Cells; ras Proteins; Tumor Cells, Cultured | 2003 |
Ubiquinone does not rescue acute myeloid leukemia cells from growth inhibition by statins.
Topics: Acute Disease; Cell Division; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lovastatin; Myelodysplastic Syndromes; Tumor Cells, Cultured; Ubiquinone | 2003 |
Inhibition of hydroxymethylglutaryl coenzyme A reductase activity induces a paradoxical increase in DNA synthesis in myeloid leukemia cells.
Topics: Cell Cycle; Cells, Cultured; Cholesterol; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Leukemia, Myeloid; Lovastatin | 1991 |