Compounds > mevastatin
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mevastatin and Leukemia, Myeloid

mevastatin has been researched along with Leukemia, Myeloid in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Appelbaum, FR; Banker, DE; Li, HY; Willman, CL; Zager, RA1
Appelbaum, FR; Banker, DE; Stirewalt, DL; Willman, CL; Zager, RA1
Burke, LP; Lewis, LD; Perez, RP1
Hohl, RJ; Larson, RA; Mannickarottu, V; Yachnin, S1

Other Studies

4 other study(ies) available for mevastatin and Leukemia, Myeloid

ArticleYear
Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses.
    Blood, 2003, May-01, Volume: 101, Issue:9

    Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Cytarabine; Daunorubicin; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lipoproteins, LDL; Lovastatin; Membrane Lipids; Protein Prenylation; Protein Processing, Post-Translational; Radiation-Sensitizing Agents; Tricarboxylic Acids; Tumor Cells, Cultured

2003
Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression.
    Leukemia research, 2003, Volume: 27, Issue:2

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Case-Control Studies; Cell Survival; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lovastatin; Mutation; Myeloid Cells; ras Proteins; Tumor Cells, Cultured

2003
Ubiquinone does not rescue acute myeloid leukemia cells from growth inhibition by statins.
    Leukemia, 2003, Volume: 17, Issue:1

    Topics: Acute Disease; Cell Division; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lovastatin; Myelodysplastic Syndromes; Tumor Cells, Cultured; Ubiquinone

2003
Inhibition of hydroxymethylglutaryl coenzyme A reductase activity induces a paradoxical increase in DNA synthesis in myeloid leukemia cells.
    Blood, 1991, Mar-01, Volume: 77, Issue:5

    Topics: Cell Cycle; Cells, Cultured; Cholesterol; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Leukemia, Myeloid; Lovastatin

1991