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mevastatin and Disease Models, Animal

mevastatin has been researched along with Disease Models, Animal in 9 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Alberts, AW; Bostedor, R; Chao, YS; Duggan, ME; Fitzpatrick, SL; Halczenko, W; Hartman, GD; Imagire, JS; Pitzenberger, SM; Smith, RL1
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Egger, AN; Glinos, GD; Jozic, I; Kirsner, RS; Pastar, I; Sawaya, AP; Stojadinovic, O; Stone, RC; Tomic-Canic, M1
Echigo, S; Hirotani, H; Shinoda, H; Sugazaki, M; Takeyama, S1
Bosch, J; García-Cardeña, G; García-Pagán, JC; Gracia-Sancho, J; Hide, D; Marrone, G; Rosado, E; Russo, L1
Catalano, R; Cordell, B; Naidu, A; Xu, Q1
Ertunc, M; Kavalali, ET; Liu, X; Wasser, CR1
Amin-Hanjani, S; Huang, PL; Liao, JK; Moskowitz, MA; Stagliano, NE; Yamada, M1

Other Studies

9 other study(ies) available for mevastatin and Disease Models, Animal

ArticleYear
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 9. The synthesis and biological evaluation of novel simvastatin analogs.
    Journal of medicinal chemistry, 1992, Oct-16, Volume: 35, Issue:21

    Topics: Administration, Oral; Animals; Anticholesteremic Agents; Disease Models, Animal; Dogs; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Magnetic Resonance Spectroscopy; Rats; Simvastatin; Structure-Activity Relationship

1992
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Mevastatin promotes healing by targeting caveolin-1 to restore EGFR signaling.
    JCI insight, 2019, 12-05, Volume: 4, Issue:23

    Topics: Animals; Caveolin 1; Cell Movement; Cell Proliferation; Diabetic Foot; Disease Models, Animal; ErbB Receptors; Female; Humans; Keratinocytes; Lovastatin; Phenotype; Signal Transduction; Skin; Swine; Wound Healing

2019
Effects of mevastatin on grafted bone in MRL/MpJ mice.
    Connective tissue research, 2010, Volume: 51, Issue:2

    Topics: Administration, Topical; Animals; Anticholesteremic Agents; Bone Density; Bone Morphogenetic Protein 2; Bone Transplantation; Cell Count; Disease Models, Animal; Lovastatin; Male; Mice; Mice, Inbred MRL lpr; Osteoclasts; Osteogenesis; RANK Ligand; RNA, Messenger; Tibia; Up-Regulation

2010
The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial-stellate cell deactivation induced by statins.
    Journal of hepatology, 2013, Volume: 58, Issue:1

    Topics: Animals; Atorvastatin; Cell Communication; Disease Models, Animal; Endothelial Cells; Gene Expression; Hepatic Stellate Cells; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Kruppel-Like Transcription Factors; Liver; Liver Circulation; Liver Cirrhosis, Experimental; Lovastatin; Male; Paracrine Communication; Pyrroles; Rats; Rats, Wistar; Simvastatin; Stress, Mechanical

2013
Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Alkyl and Aryl Transferases; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Apolipoproteins E; Astrocytes; Brain; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Farnesyltranstransferase; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Mice, Transgenic; Microglia; Neuroglia; Polyisoprenyl Phosphates; Protein Prenylation

2002
Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling.
    The Journal of physiology, 2007, Mar-01, Volume: 579, Issue:Pt 2

    Topics: Animals; beta-Cyclodextrins; Cells, Cultured; Cholesterol; Disease Models, Animal; Evoked Potentials; Hippocampus; Intracellular Signaling Peptides and Proteins; Lovastatin; Mice; Mice, Knockout; Neuroglia; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Proteins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Synaptic Vesicles; Vesicle-Associated Membrane Protein 2

2007
Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice.
    Stroke, 2001, Volume: 32, Issue:4

    Topics: Animals; Aorta; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Cerebrovascular Circulation; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Lovastatin; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; RNA, Messenger; Stroke; Treatment Outcome; Up-Regulation

2001