mevalonic acid and Pregnancy

mevalonic acid has been researched along with Pregnancy in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199024 (53.33)18.7374
1990's10 (22.22)18.2507
2000's6 (13.33)29.6817
2010's3 (6.67)24.3611
2020's2 (4.44)2.80

Authors

AuthorsStudies
Barberio, L; Bertoli, S; Gagliardi, S; Leone, A; Mandalà, M; Pallottini, V; Segatto, M; Tonini, C1
Barszczyk, A; Charlton, MP; Feng, ZP; Quan, Y; Sun, HS; Zheng, W1
Dovzhikova, IV; Lutsenko, MT1
Caniggia, I; Ermini, L; Post, M1
Gotoda, T; Harada, K; Iizuka, Y; Ishibashi, S; Kitamine, T; Ohashi, K; Okazaki, H; Osuga, J; Sekiya, M; Shimano, H; Tamura, Y; Tomita, S; Tozawa, R; Yagyu, H; Yahagi, N; Yamada, N1
Butenhoff, JL; Hansen, KJ; Luebker, DJ; Moore, JA; York, RG1
Karperien, M; Löwik, C; Papapoulos, S; van Beek, E1
Cuisset, L; Guffon, N; Le Bozec, J; Rolland, MO; Vianey-Saban, C1
Hatton, J; Middleton, B; White, DA2
Bhavnani, BR1
Boguslawski, W; Sokolowski, W1
Rabinowitz, JL; Tulenko, TN1
Feingold, KR; MacRae, G; Siperstein, MD; Wiley, MH1
Durham, SK; Flint, OP; Gregg, RE; Masters, BA; Palmoski, MJ; Wang-Iverson, D1
Cox, RH; Hartman, HA; Hrab, RV1
Brewer, LM; Brown, NA; Sheardown, SA1
Durham, SK; Flint, OP; Gregg, RE; Masters, BA2
Buckingham, B; Gibson, KM; Hoffmann, GF; Sweetman, L1
Löwik, C; Papapoulos, S; van beek, E; van der Pluijm, G1
Hirai, A; Kitagawa, M; Morio, H; Moroo, I; Nakamura, S; Noguchi, Y; Saito, Y; Tanaka, T; Tatsuno, I; Uchida, D; Yasuda, T1
Getz, B; Ingle, JN; Karpeisky, MY; Mikhailov, SN; Padyukova, NSh; Reinholz, GG; Sanders, ES; Spelsberg, TC1
Bhavnani, BR; Woolever, CA1
Ramachandran, CK; Shah, SN1
Caspi, E; Forbes, WB; Wittstruck, TA; Woodward, BE1
Cook, LJ; Hood, RL; Mills, SC; Nestel, PJ; Poyser, A; Scott, TW; Willis, MR1
Brendel, SU; Gibson, KM; Hoffmann, GF; Scharfschwerdt, SR; Shin, YS; Speidel, IM1
Bremer, HJ; Hoffmann, GF; Hunneman, DH; Hyánek, J; Kozich, V; Lehnert, W; Nyhan, WL; Speidel, I; Sweetman, L; Trefz, FK1
Hoffmann, GF; Sweetman, L1
Bader, PI; Brandt, IK; Gibson, KM; Hoffmann, G; Sweetman, L; Wappner, RS1
Keller, RK; Simonet, WS1
Conti Devirgiliis, L; Leoni, S; Mangiantini, MT; Spagnuolo, S; Trentalance, A; Valbonesi, M1
Gianelly, AA; Terner, C1
van Leusden, HA; Villee, CA1
Bhavnani, BR; Short, RV1
Johnson, RC; Shah, SN1
Shah, SN1
Edmond, J; Popják, G1
Edmond, J1
Van Leusden, H; Villee, CA; Zelewski, L1
Popják, G1
McNamara, DJ; Quackenbush, FW; Rodwell, VW1
Harris, DN; Hilf, R; Lerner, LJ; Michel, I; Yiacas, E1

Reviews

3 review(s) available for mevalonic acid and Pregnancy

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023
Statins, Mevalonate Pathway and its Intermediate Products in Placental Development and Preeclampsia.
    Current molecular pharmacology, 2017, Volume: 10, Issue:2

    Topics: Animals; Cell Movement; Cell Proliferation; Female; Glycosylation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Mice; Placentation; Pre-Eclampsia; Pregnancy; Prenylation; Terpenes

2017
The regulation of the biosynthesis of sterols and steroids in the placenta.
    Advances in enzyme regulation, 1966, Volume: 4

    Topics: Acetates; Carbon Isotopes; Cholesterol; Chorionic Gonadotropin; Chromatography; Chromatography, Thin Layer; Crystallization; Female; Humans; In Vitro Techniques; Mevalonic Acid; Placenta; Pregnancy; Pregnenolone; Squalene; Steroids; Sterols; Tritium

1966

Trials

1 trial(s) available for mevalonic acid and Pregnancy

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023

Other Studies

42 other study(ies) available for mevalonic acid and Pregnancy

ArticleYear
Maternal Dietary Exposure to Low-Dose Bisphenol A Affects Metabolic and Signaling Pathways in the Brain of Rat Fetuses.
    Nutrients, 2020, May-17, Volume: 12, Issue:5

    Topics: Animals; Benzhydryl Compounds; Brain; Diet; Dietary Exposure; Female; Fetus; Maternal Exposure; Maternal Nutritional Physiological Phenomena; Mevalonic Acid; Phenols; Pregnancy; Rats; Signal Transduction

2020
Differential roles of the mevalonate pathway in the development and survival of mouse Purkinje cells in culture.
    Molecular neurobiology, 2015, Volume: 51, Issue:3

    Topics: Animals; Cell Differentiation; Cell Survival; Cells, Cultured; Female; Lovastatin; Mevalonic Acid; Mice; Pregnancy; Purkinje Cells; Signal Transduction

2015
A Method for Detection of Cholesterol Synthesis in the Placenta during Exacerbation of Cytomegalovirus Infection.
    Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1

    Topics: Adult; Case-Control Studies; Cholesterol; Cytomegalovirus Infections; Disease Progression; Female; Gonadal Steroid Hormones; Humans; Hydroxysteroid Dehydrogenases; Mevalonic Acid; Placenta; Placental Insufficiency; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Squalene

2015
Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene.
    The Journal of biological chemistry, 2003, Oct-31, Volume: 278, Issue:44

    Topics: Alleles; Animals; Blotting, Northern; Cells, Cultured; Cholesterol; Embryo, Mammalian; Exons; Female; Fibroblasts; Genetic Vectors; Genotype; Heterozygote; Homozygote; Hydroxymethylglutaryl CoA Reductases; Lipoproteins; Liver; Maternal Exposure; Mevalonic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Models, Genetic; Mutagenesis, Site-Directed; Phenotype; Pregnancy; Pregnancy, Animal; Time Factors

2003
Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague-Dawley rats: dose-response, and biochemical and pharamacokinetic parameters.
    Toxicology, 2005, Nov-05, Volume: 215, Issue:1-2

    Topics: Alkanesulfonic Acids; Animals; Animals, Newborn; Birth Weight; Blood Glucose; Dose-Response Relationship, Drug; Female; Fluorocarbons; Lipids; Liver; Male; Mevalonic Acid; Milk; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Thyroid Hormones; Toxicity Tests

2005
Independent pathways in the modulation of osteoclastic resorption by intermediates of the mevalonate biosynthetic pathway: the role of the retinoic acid receptor.
    Bone, 2006, Volume: 38, Issue:2

    Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Calcium; Diphosphonates; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Ibandronic Acid; Mevalonic Acid; Mice; Osteoclasts; Polyisoprenyl Phosphates; Pregnancy; Protein Prenylation; Receptors, Retinoic Acid

2006
First-trimester enzymatic and molecular prenatal diagnosis of mevalonic aciduria.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:6

    Topics: Chorionic Villi; Consanguinity; Creatinine; DNA; Exons; Female; Fibroblasts; Genotype; Heterozygote; Homozygote; Humans; Metabolism, Inborn Errors; Mevalonic Acid; Mutation; Phosphotransferases (Alcohol Group Acceptor); Pregnancy; Pregnancy Trimester, First; Prenatal Diagnosis; Risk; Serine

2005
A mevalonate requirement for maintenance of fatty acid and protein synthesis during hormonally stimulated development of mammary gland in vitro.
    The Journal of biological chemistry, 1984, Aug-25, Volume: 259, Issue:16

    Topics: Acetates; Acetic Acid; Animals; Carbon Radioisotopes; Fatty Acids; Female; Hydroxymethylglutaryl CoA Reductases; Insulin; Leucine; Lovastatin; Mammary Glands, Animal; Mevalonic Acid; Microsomes; Naphthalenes; Organ Culture Techniques; Pregnancy; Prolactin; Protein Biosynthesis; Rabbits; Tritium

1984
Oestrogen biosynthesis in the pregnant mare.
    The Journal of endocrinology, 1981, Volume: 89 Suppl

    Topics: Acetates; Alkenes; Androstenedione; Animals; Chemical Phenomena; Chemistry; Cholesterol; Dehydroepiandrosterone; Equilin; Estrogens; Farnesol; Female; Hemiterpenes; Horses; Maternal-Fetal Exchange; Mevalonic Acid; Organophosphorus Compounds; Polyisoprenyl Phosphates; Pregnancy; Pregnancy, Animal; Sesquiterpenes; Squalene; Tyrosine

1981
HMG-CoA reductase activity in the microsomal fraction from human placenta in early and term pregnancy.
    The International journal of biochemistry, 1984, Volume: 16, Issue:9

    Topics: Acetates; Female; Gestational Age; Humans; Hydroxymethylglutaryl CoA Reductases; Liver; Mevalonic Acid; Microsomes; Placenta; Pregnancy; Sterols

1984
Metabolism of C14 mevalonate by adult and fetal arteries.
    Artery, 1983, Volume: 11, Issue:6

    Topics: Acyl Coenzyme A; Animals; Aorta, Thoracic; Cholesterol; Female; Fetus; Gestational Age; Mevalonic Acid; Oleic Acid; Oleic Acids; Palmitic Acid; Palmitic Acids; Pregnancy; Rabbits; Stearic Acids; Umbilical Arteries

1983
Mevalonate metabolism in pregnant rats.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:9

    Topics: Animals; Carbon Dioxide; Cholesterol; Female; Fetus; Kidney; Liver; Mevalonic Acid; Placenta; Pregnancy; Pregnancy, Animal; Rats; Sterols; Time Factors

1980
The control of sterol synthesis during development of rabbit mammary gland.
    The Journal of biological chemistry, 1981, May-25, Volume: 256, Issue:10

    Topics: Acetates; Animals; Female; Hydrocortisone; Insulin; Kinetics; Lactation; Mammary Glands, Animal; Mevalonic Acid; Organ Culture Techniques; Pregnancy; Prolactin; Rabbits; Sterols

1981
In vitro myotoxicity of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, pravastatin, lovastatin, and simvastatin, using neonatal rat skeletal myocytes.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:1

    Topics: Animals; Anticholesteremic Agents; Blood Proteins; Cells, Cultured; Cholesterol; Drug Stability; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Mevalonic Acid; Muscle, Skeletal; Pravastatin; Pregnancy; Protein Binding; Rats; Rats, Sprague-Dawley; Simvastatin

1995
Prevention of fluvastatin-induced toxicity, mortality, and cardiac myopathy in pregnant rats by mevalonic acid supplementation.
    Teratology, 1994, Volume: 50, Issue:1

    Topics: Analysis of Variance; Animals; Birth Weight; Cardiomyopathies; Cholesterol; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fatty Acids, Monounsaturated; Female; Fertility; Fetal Death; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Litter Size; Mevalonic Acid; Obstetric Labor Complications; Pregnancy; Pregnancy Complications, Cardiovascular; Puerperal Disorders; Rats; Rats, Sprague-Dawley; Weight Loss

1994
HMG-CoA reductase mRNA in the post-implantation rat embryo studied by in situ hybridization.
    Teratology, 1993, Volume: 47, Issue:2

    Topics: Animals; Embryo, Mammalian; Female; Gene Expression; Gestational Age; Hydroxymethylglutaryl CoA Reductases; In Situ Hybridization; Mevalonic Acid; Pregnancy; Rats; Rats, Wistar; RNA Probes; RNA, Messenger; Tissue Distribution

1993
Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
    Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anticholesteremic Agents; Butylamines; Cells, Cultured; Cholesterol; Diterpenes; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Muscle, Skeletal; Pravastatin; Pregnancy; Prodrugs; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Squalene; Sulfonic Acids

1997
HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgeranylation of low-molecular-weight proteins in neonatal rat muscle cell culture.
    Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1

    Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Autoradiography; Cells, Cultured; Cholesterol; Densitometry; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isotope Labeling; Lovastatin; Mevalonic Acid; Molecular Weight; Muscle Proteins; Muscle, Skeletal; Polyisoprenyl Phosphates; Pravastatin; Pregnancy; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Scintillation Counting; Sesquiterpenes; Tritium

1997
Mevalonate kinase deficiency in a dizygotic twin with mild mevalonic aciduria.
    Journal of inherited metabolic disease, 1997, Volume: 20, Issue:3

    Topics: Cells, Cultured; Female; Humans; Lymphocytes; Mevalonic Acid; Phosphotransferases (Alcohol Group Acceptor); Pregnancy; Twins, Dizygotic

1997
The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1999, Volume: 14, Issue:5

    Topics: Animals; Bone and Bones; Bone Resorption; Culture Techniques; Diphosphonates; Dose-Response Relationship, Drug; Female; Ibandronic Acid; Lovastatin; Mevalonic Acid; Mice; Models, Chemical; Nitrogen; Pregnancy; Protein Prenylation

1999
Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Apr-15, Volume: 20, Issue:8

    Topics: Animals; Cell Count; Cell Death; Cells, Cultured; DNA Fragmentation; Female; Fetus; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Neurons; Polyisoprenyl Phosphates; Pregnancy; Prosencephalon; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Signal Transduction; Time Factors; Tumor Suppressor Protein p53

2000
Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue.
    Breast cancer research and treatment, 2002, Volume: 71, Issue:3

    Topics: Bone and Bones; Breast Neoplasms; Cell Differentiation; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Female; Humans; Imidazoles; Lovastatin; Mevalonic Acid; Osteoblasts; Pregnancy; Structure-Activity Relationship; Tumor Cells, Cultured; Zoledronic Acid

2002
Formation of steroids by the pregnant mare. VI. Metabolism of [14C]farnesyl pyrophosphate and [3H]dehydroepiandrosterone injected into the fetus.
    Endocrinology, 1978, Volume: 103, Issue:6

    Topics: Animals; Dehydroepiandrosterone; Farnesol; Female; Fetus; Horses; Maternal-Fetal Exchange; Mevalonic Acid; Polyisoprenyl Phosphates; Pregnancy; Pregnancy, Animal; Sesquiterpenes; Steroids

1978
Decarboxylation of mevalonate pyrophosphate is one rate-limiting step in hepatic cholesterol synthesis in suckling and weaned rats.
    Biochemical and biophysical research communications, 1976, Mar-08, Volume: 69, Issue:1

    Topics: Aging; Animals; Cholesterol; Cholesterol, Dietary; Female; Kinetics; Lactation; Liver; Mevalonic Acid; Organophosphorus Compounds; Phosphotransferases; Pregnancy; Rats

1976
Influence of prenatal and continuous postnatal protein-deficient diets on the development of rats.
    Biology of the neonate, 1979, Volume: 35, Issue:1-2

    Topics: Animals; Animals, Newborn; Body Weight; Brain; Cerebellum; Dietary Proteins; Female; Male; Maternal-Fetal Exchange; Mevalonic Acid; Organ Size; Pregnancy; Protein Deficiency; Rats; Sterols

1979
The effect of dietary fat supplements on cholesterol metabolism in ruminants.
    Journal of lipid research, 1978, Volume: 19, Issue:7

    Topics: Acetates; Animals; Cholesterol; Dietary Fats; Feces; Female; Goats; Kinetics; Lactation; Lipoproteins; Mevalonic Acid; Pregnancy; Sheep; Sterols

1978
Mevalonate kinase assay using DEAE-cellulose column chromatography for first-trimester prenatal diagnosis and complementation analysis in mevalonic aciduria.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:5

    Topics: Chorionic Villi; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Thin Layer; Female; Fibroblasts; Humans; Metabolism, Inborn Errors; Mevalonic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Pregnancy; Pregnancy Trimester, First; Prenatal Diagnosis

1992
Facts and artefacts in mevalonic aciduria: development of a stable isotope dilution GCMS assay for mevalonic acid and its application to physiological fluids, tissue samples, prenatal diagnosis and carrier detection.
    Clinica chimica acta; international journal of clinical chemistry, 1991, May-15, Volume: 198, Issue:3

    Topics: Adult; Amniotic Fluid; Cell Line; Child; Cholesterol; Female; Fetal Diseases; Fetus; Gas Chromatography-Mass Spectrometry; Heterozygote; Humans; Indicator Dilution Techniques; Infant; Infant, Newborn; Male; Mevalonic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Pregnancy; Prenatal Diagnosis; Sensitivity and Specificity

1991
An improved chemical ionization assay for mevalonic acid.
    Biomedical & environmental mass spectrometry, 1990, Volume: 19, Issue:8

    Topics: Amniotic Fluid; Chromatography, Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Mevalonic Acid; Pregnancy

1990
Mevalonic aciduria--an inborn error of cholesterol and nonsterol isoprene biosynthesis.
    The New England journal of medicine, 1986, Jun-19, Volume: 314, Issue:25

    Topics: Amniotic Fluid; Cataract; Child, Preschool; Cholesterol; Failure to Thrive; Female; Fetal Diseases; Humans; Male; Metabolism, Inborn Errors; Mevalonic Acid; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Pregnancy; Prenatal Diagnosis; Sterols; Terpenes

1986
Near normal levels of isoprenoid lipids in severe mevalonic aciduria.
    Biochemical and biophysical research communications, 1988, Apr-29, Volume: 152, Issue:2

    Topics: Cholesterol; Dolichol Phosphates; Female; Fetal Diseases; Humans; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Metabolism, Inborn Errors; Mevalonic Acid; Polyisoprenyl Phosphates; Pregnancy; Squalene

1988
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate and cholesterol in isolated rat hepatocytes during perinatal development.
    Cellular and molecular biology, 1986, Volume: 32, Issue:3

    Topics: Aging; Animals; Cholesterol; Female; Hydroxymethylglutaryl CoA Reductases; Liver; Mevalonic Acid; Microsomes, Liver; Pregnancy; Rats

1986
Inhibition of cholesterol biosynthesis by dehydroepiandrosterone in lactating mammary gland.
    Endocrinology, 1968, Volume: 83, Issue:6

    Topics: Acetates; Animals; Antimetabolites; Carbon Isotopes; Cholestanes; Cholesterol; Chromatography, Thin Layer; Dehydroepiandrosterone; Depression, Chemical; Digitalis Glycosides; Female; Glucosephosphate Dehydrogenase; Glycerides; Guinea Pigs; In Vitro Techniques; Lactation; Mammary Glands, Animal; Mevalonic Acid; Polycyclic Compounds; Pregnancy; Squalene; Sterols

1968
Formation of estrogens by hydatidiform moles in vitro.
    The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:8

    Topics: Carbon Isotopes; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Humans; Hydatidiform Mole; In Vitro Techniques; Mevalonic Acid; Pregnancy; Pregnenolone; Tritium

1966
Formation of steroids by the pregnant mare. IV. Metabolism of 14 C-mevalonic acid and 3 H-dehydroisoandrosterone injected into the fetal circulation.
    Endocrinology, 1973, Volume: 92, Issue:5

    Topics: 17-Ketosteroids; Animals; Carbon Isotopes; Dehydroepiandrosterone; Estradiol; Estrone; Female; Fetus; Horses; Maternal-Fetal Exchange; Mevalonic Acid; Pregnancy; Pregnanediol; Pregnanes; Tritium

1973
Hepatic cholesterol synthesis from mevalonate and squalwne in rats: effect of feeding cholesterol supplemented diet during weaning and following starvation.
    Lipids, 1974, Volume: 9, Issue:12

    Topics: Age Factors; Animals; Cholesterol; Cholesterol, Dietary; Female; Lactation; Liver; Mevalonic Acid; Microsomes, Liver; Pregnancy; Rats; Squalene; Starvation; Weaning

1974
Regulation of hepatic cholesterol synthesis from mevalonate in suckling and weaned rats.
    Lipids, 1973, Volume: 8, Issue:5

    Topics: Age Factors; Animal Nutritional Physiological Phenomena; Animals; Carbon Isotopes; Chemical Precipitation; Cholesterol; Chromatography, Thin Layer; Digitonin; Dose-Response Relationship, Drug; Female; Lactation; Lipids; Liver; Mevalonic Acid; Organ Size; Pregnancy; Rats; Squalene; Sterols; Time Factors; Weaning

1973
Transfer of carbon atoms from mevalonate to n-fatty acids.
    The Journal of biological chemistry, 1974, Jan-10, Volume: 249, Issue:1

    Topics: Acetoacetates; Anaerobiosis; Animals; Brain; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Female; Glutarates; Liver; Lung; Mevalonic Acid; Oleic Acids; Organ Specificity; Palmitic Acids; Pregnancy; Rats; Skin; Spinal Cord; Stearic Acids; Time Factors

1974
Ketone bodies as precursors of sterols and fatty acids in the developing rat.
    The Journal of biological chemistry, 1974, Jan-10, Volume: 249, Issue:1

    Topics: Acetates; Acetoacetates; Animals; Body Weight; Brain; Chromatography, Gas; Fatty Acids; Female; Hydroxybutyrates; Kidney; Liver; Lung; Mevalonic Acid; Organ Size; Organ Specificity; Pregnancy; Rats; Skin; Spinal Cord; Sterols; Time Factors

1974
Lessons learnt from small molecules.
    Biochemical Society symposium, 1970, Volume: 30

    Topics: Acetates; Animals; Biochemistry; Cholesterol; Farnesol; Fatty Acids; Female; Glycerol; Goats; History, 20th Century; Kinetics; Lactation; Lactose; Mammary Glands, Animal; Mevalonic Acid; Pregnancy; Rabbits; Radioisotopes; Transferases; Triglycerides; United Kingdom

1970
Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. Developmental pattern.
    The Journal of biological chemistry, 1972, Sep-25, Volume: 247, Issue:18

    Topics: Alcohol Oxidoreductases; Animals; Animals, Newborn; Bile Ducts; Carbon Isotopes; Cholesterol; Circadian Rhythm; Cycloheximide; Embryonic and Fetal Development; Female; Gestational Age; Glutarates; Growth Hormone; Hydrocortisone; Liver; Male; Mevalonic Acid; Microsomes, Liver; Milk; Pregnancy; Rats; Thyroxine; Weaning

1972
Cholesterol synthesis inhibitor showing reduction of lipids and hormone antagonism.
    The American journal of clinical nutrition, 1970, Volume: 23, Issue:9

    Topics: Animals; Anticholesteremic Agents; Estrogen Antagonists; Estrus; Ethylamines; Female; Mevalonic Acid; Pregnancy

1970