mevalonic acid and Niemann-Pick Disease

mevalonic acid has been researched along with Niemann-Pick Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Distl, R; Glöckner, F; Meske, V; Ohm, TG; Schönheit, B; Tamanai, M; Treiber-Held, S1
Brunk, U; Dallner, G; Pentchev, PG; Schedin, S1
Blanchette-Mackie, J; Brady, RO; Brewer, HB; Carstea, ED; Cooper, PS; Neufeld, EB; Pentchev, PG; Phair, RD; Schwartz, CC; Shamburek, RD; VandenBroek, JM; Zech, LA1
Chojnacki, T; Dallner, G; Nilsson, M; Schedin, S1
Faust, JR; Liscum, L; Ruggiero, RM1
Comly, ME; Kruth, HS; Patel, S; Pentchev, PG; Proestel, M; Weintroub, H1

Other Studies

6 other study(ies) available for mevalonic acid and Niemann-Pick Disease

ArticleYear
Cholesterol and tau protein--findings in Alzheimer's and Niemann Pick C's disease.
    Pharmacopsychiatry, 2003, Volume: 36 Suppl 2

    Topics: Acyl Coenzyme A; Alzheimer Disease; Analysis of Variance; Animals; Anticholesteremic Agents; Astrocytes; Blotting, Western; Brain Chemistry; Calcium; Cerebral Cortex; Cholesterol; Dextrans; Drug Interactions; Filipin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Lovastatin; Mevalonic Acid; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microglia; Microtubules; Neurofibrillary Tangles; Neurons; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Proteins; rho GTP-Binding Proteins; RNA, Messenger; tau Proteins; Tubulin

2003
Changes in the levels of dolichol and dolichyl phosphate in a murine model of Niemann-Pick's type C disease.
    Journal of neurochemistry, 1995, Volume: 65, Issue:2

    Topics: Animals; Cholesterol; Dolichol Phosphates; Dolichols; Mevalonic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron; Niemann-Pick Diseases; Subcellular Fractions; Tissue Distribution; Ubiquinone

1995
Intracellular trafficking of the free cholesterol derived from LDL cholesteryl ester is defective in vivo in Niemann-Pick C disease: insights on normal metabolism of HDL and LDL gained from the NP-C mutation.
    Journal of lipid research, 1997, Volume: 38, Issue:12

    Topics: Adult; Bile; Cholesterol; Cholesterol Esters; Fibroblasts; Histocytochemistry; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Mevalonic Acid; Mutation; Niemann-Pick Diseases

1997
Alterations in the biosynthesis of cholesterol, dolichol and dolichyl-P in the genetic cholesterol homeostasis disorder, Niemann-Pick type C disease.
    Biochimica et biophysica acta, 1998, Nov-02, Volume: 1394, Issue:2-3

    Topics: Animals; Brain; Cholesterol; Disease Models, Animal; Dolichol Phosphates; Dolichols; Farnesyl-Diphosphate Farnesyltransferase; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Mevalonic Acid; Mice; Mice, Inbred BALB C; Microsomes, Liver; Niemann-Pick Diseases; Squalene; Transferases; Tritium

1998
The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts.
    The Journal of cell biology, 1989, Volume: 108, Issue:5

    Topics: Cell Division; Cells, Cultured; Cholesterol, LDL; Fibroblasts; Humans; Kinetics; Lipoproteins, LDL; Lysosomes; Mevalonic Acid; Niemann-Pick Diseases; Reference Values; Subcellular Fractions; Tritium

1989
The cholesterol storage disorder of the mutant BALB/c mouse. A primary genetic lesion closely linked to defective esterification of exogenously derived cholesterol and its relationship to human type C Niemann-Pick disease.
    The Journal of biological chemistry, 1986, Feb-25, Volume: 261, Issue:6

    Topics: Animals; Cholesterol Esters; Desmosterol; Disease Models, Animal; Fibroblasts; Heterozygote; Homozygote; Lipoproteins, LDL; Mevalonic Acid; Mice; Mice, Inbred BALB C; Mutation; Niemann-Pick Diseases; Squalene

1986