mevalonic acid has been researched along with Invasiveness, Neoplasm in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Akrap, N; Andersson, D; Buffa, F; Choudhry, H; Garre, E; Harris, A; Harrison, H; Jonasson, E; Landberg, G; Magnusson, Y; Rafnsdottir, S; Ragoussis, J; Ståhlberg, A; Walsh, CA | 1 |
| Chan, CW; Goh, BC; Hartman, M; Lee, SC; Loh, X; Seah, S; Wang, T | 1 |
| Fukuda, M; Handa, H; Hashimoto, A; Hashimoto, S; Nam, JM; Oikawa, T; Okada, M; Oneyama, C; Onodera, Y; Otsuka, Y; Sabe, H; Sugino, H; Yoshikawa, A | 1 |
| Hida, T; Horio, Y; Murakami-Tonami, Y; Osada, H; Sekido, Y; Tanaka, K | 1 |
| Bifulco, M; Laezza, C; Malfitano, AM; Pisanti, S | 1 |
| Inoue, M; Kusama, T; Matsumoto, Y; Mukai, M; Nakamura, H; Tatsuta, M | 1 |
| Andela, VB | 1 |
| Hirano, K; Iguchi, K; Nakano, T; Usui, S | 1 |
| Chellaiah, MA; Desai, B; Rogers, MJ | 1 |
| Kakehata, S; Maruya, S; Mizukami, H; Myers, JN; Shinkawa, H; Shirasaki, T; Takahata, T; Takeda, I; Yagihashi, S | 1 |
| Liu, L; Prasanna, P; Samid, D; Thibault, A | 1 |
| Lin, JK; Lin-Shiau, SY; Wang, IK | 1 |
| Härkönen, PL; Lakkakorpi, PT; Väänänen, HK; Virtanen, SS | 1 |
13 other study(ies) available for mevalonic acid and Invasiveness, Neoplasm
| Article | Year |
|---|---|
The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cohort Studies; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxymethylglutaryl-CoA Synthase; Lymph Nodes; Metabolic Networks and Pathways; Mevalonic Acid; Models, Biological; Neoplasm Invasiveness; Neoplastic Stem Cells | 2020 |
Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway.
Topics: Adult; Aged; Apoptosis; Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoenzyme Techniques; Mevalonic Acid; Middle Aged; Mitogen-Activated Protein Kinases; Neoplasm Grading; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Prognosis; Prospective Studies; Proto-Oncogene Proteins c-akt; Simvastatin; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2016 |
P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; gamma-Glutamyltransferase; HEK293 Cells; Humans; MCF-7 Cells; Mevalonic Acid; Neoplasm Invasiveness; Neoplasm Metastasis; rab GTP-Binding Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Suppressor Protein p53 | 2016 |
Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Gene Expression Regulation, Neoplastic; Hippo Signaling Pathway; Humans; Hyaluronan Receptors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mevalonic Acid; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Neurofibromin 2; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA Interference; Signal Transduction; Simvastatin; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; YAP-Signaling Proteins | 2017 |
The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway.
Topics: Actins; Amides; Arachidonic Acids; Blotting, Western; Breast Neoplasms; Cannabinoids; Cell Membrane; Cell Movement; Cytoskeleton; Cytosol; Female; Fluorescent Antibody Technique; Humans; Mevalonic Acid; Neoplasm Invasiveness; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2008 |
Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor.
Topics: Alkyl and Aryl Transferases; Benzamides; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Humans; Methionine; Mevalonic Acid; Neoplasm Invasiveness; Pancreatic Neoplasms; Protein Prenylation; Signal Transduction; Tumor Cells, Cultured | 2003 |
Correspondence Re S. S. Virtanen et al., Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway. Cancer Res 2002;62:2708-14. Re K. Sawada et al., Alendronate inhibits lysophosphatidic acid-induced migration of huma
Topics: Alendronate; Humans; Male; Mevalonic Acid; Neoplasm Invasiveness; Prostatic Neoplasms | 2004 |
Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells.
Topics: Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cytosol; Diphosphonates; Enzyme Inhibitors; Humans; Leucine; Male; Mevalonic Acid; Neoplasm Invasiveness; Neoplasm Metastasis; rap1 GTP-Binding Proteins | 2006 |
Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells.
Topics: Adenocarcinoma; Bone Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Diphosphonates; Enzyme Activation; Giant Cells; Humans; Hyaluronan Receptors; Integrin alphaVbeta3; Male; Matrix Metalloproteinase 9; Mevalonic Acid; Mutant Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Osteopontin; Prostatic Neoplasms; Protein Prenylation; RANK Ligand; Recombinant Fusion Proteins; rho GTP-Binding Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction | 2007 |
Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells.
Topics: Anticholesteremic Agents; Carcinoma, Squamous Cell; Caspase 3; Cell Proliferation; Cell Survival; Focal Adhesion Kinase 1; G1 Phase; Head and Neck Neoplasms; Humans; Integrin beta1; Mevalonic Acid; Neoplasm Invasiveness; Phosphorylation; Signal Transduction; Simvastatin; Tumor Cells, Cultured | 2007 |
Lipid metabolism as a target for brain cancer therapy: synergistic activity of lovastatin and sodium phenylacetate against human glioma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Division; Drug Synergism; Glioma; Humans; Lipid Metabolism; Lovastatin; Mevalonic Acid; Neoplasm Invasiveness; Phenylacetates; Tumor Cells, Cultured; Ubiquinone | 1996 |
Suppression of invasion and MMP-9 expression in NIH 3T3 and v-H-Ras 3T3 fibroblasts by lovastatin through inhibition of ras isoprenylation.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Membrane; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Electrophoresis; Gene Expression; Genes, ras; Lovastatin; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mevalonic Acid; Mice; Neoplasm Invasiveness; NF-kappa B; Promoter Regions, Genetic; Protein Prenylation; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-1; Transcription, Genetic | 2000 |
Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
Topics: Alendronate; Antimetabolites; Bone Neoplasms; Cell Movement; Clodronic Acid; Dose-Response Relationship, Drug; Humans; Male; Mevalonic Acid; Neoplasm Invasiveness; Prostatic Neoplasms; Tumor Cells, Cultured | 2002 |