Compounds > mevalonic acid

mevalonic acid and Hypertension, Pulmonary

mevalonic acid has been researched along with Hypertension, Pulmonary in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Feng, Z; Fu, G; Gong, Y; Jiang, D; Jin, T; Lu, J; Lv, Q; Wang, M; Ying, H1
Chen, Y; Fu, G; Jiang, D; Xu, S; Zhu, Y1
Liu, WH; Liu, ZH; Luo, Q; Wang, Y; Xi, QY; Xu, XH; Zhang, HL; Zhao, ZH1
Adachi, O; Fukushige, S; Horii, A; Kawamoto, S; Matsuo, S; Saiki, Y1

Other Studies

4 other study(ies) available for mevalonic acid and Hypertension, Pulmonary

ArticleYear
Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline.
    Molecular medicine (Cambridge, Mass.), 2022, 08-12, Volume: 28, Issue:1

    Topics: Animals; Autophagy; Cell Proliferation; Endothelial Cells; Geranyltranstransferase; Hypertension, Pulmonary; Mevalonic Acid; Monocrotaline; Monomeric GTP-Binding Proteins; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases

2022
Expression of key enzymes in the mevalonate pathway are altered in monocrotaline-induced pulmonary arterial hypertension in rats.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Animals; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hemodynamics; Hypertension, Pulmonary; Metabolic Networks and Pathways; Mevalonic Acid; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; rhoA GTP-Binding Protein

2017
Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:3

    Topics: Animals; Blood Pressure; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Mevalonic Acid; Monocrotaline; Polyisoprenyl Phosphates; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Signal Transduction; Simvastatin; Vascular Remodeling

2018
Single-dose rosuvastatin ameliorates lung ischemia-reperfusion injury via upregulation of endothelial nitric oxide synthase and inhibition of macrophage infiltration in rats with pulmonary hypertension.
    The Journal of thoracic and cardiovascular surgery, 2015, Volume: 149, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Disease Models, Animal; Endothelium, Vascular; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Lung Injury; Macrophages; Male; Mevalonic Acid; Monocrotaline; Nitric Oxide Synthase Type III; Oxygen; Phosphorylation; Pulmonary Edema; Pyrimidines; Rats, Sprague-Dawley; Reperfusion Injury; Rosuvastatin Calcium; Sulfonamides; Up-Regulation

2015