mevalonic acid and Disease Exacerbation

mevalonic acid has been researched along with Disease Exacerbation in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's6 (40.00)24.3611
2020's5 (33.33)2.80

Authors

AuthorsStudies
Göbel, A; Hofbauer, LC; Rachner, TD; Rauner, M1
Baker, LA; Belleau, P; Biffi, G; Brosnan, E; Cox, H; Deschênes, A; Doshi, A; Hao, Y; Hwang, CI; Khaledi, K; Krasnitz, A; Lowe, SW; Lumia, RP; Oni, TE; Park, Y; Sánchez-Rivera, FJ; Somerville, TDD; Tonelli, C; Trotman, LC; Tuveson, DA; Vakoc, CR1
Billington, EO; Reid, IR1
Brindisi, M; Cappello, AR; Fiorillo, M; Frattaruolo, L; Lisanti, MP; Sotgia, F1
Baronio, F; Beedgen, L; Brennenstuhl, H; Gleich, F; Haas, D; Hoffmann, GF; Jeltsch, K; Kölker, S; Martini, S; Nashawi, M; Opladen, T; Schröter, J; Simon, A; Thiel, C; Tsiakas, K; von Landenberg, C1
Chang, WC; Chen, L; Cheng, BH; Cheng, WC; Hung, YC; Jeng, LB; Ju, LJ; Ma, WL; Ou, YJ; Yang, MD1
Dovzhikova, IV; Lutsenko, MT1
Assaraf, YG; Bieńk, K; Cieślar-Pobuda, A; Dutta, C; Ghavami, S; Likus, W; Pakuła, M; Pathak, H; Shojaei, S; Siemianowicz, K; Wang, Q; Łos, MJ1
Pich, C; Sarrabayrouse, G; Teiti, I; Tilkin-Mariame, AF1
Lahtela, J; Murtola, TJ; Syvälä, H; Tammela, TLj; Visakorpi, T1
Aufderklamm, S; Gakis, G; Gerber, V; Hennenlotter, J; Knapp, J; Kühs, U; Merseburger, A; Schwentner, C; Stenzl, A; Todenhöfer, T; Vogel, U1
Brahmachari, S; Gendelman, HE; Ghosh, A; Jana, A; Liu, X; Pahan, K; Roy, A1
Duhamel, JF; Guillois, B; Laloum, D; Nimubona, L; Read, MH; Rolland, MO1
Christensen, M; Greco, A; Lipschutz, JH; Madaio, MP; Snyder, RW; Su, AW1
Bergsagel, PL; Boutros, PC; Bros, C; Clendening, JW; Jurisica, I; Khosravi, F; Martirosyan, A; Penn, LZ; Stewart, AK; Wong, WW1

Reviews

6 review(s) available for mevalonic acid and Disease Exacerbation

ArticleYear
Cholesterol and beyond - The role of the mevalonate pathway in cancer biology.
    Biochimica et biophysica acta. Reviews on cancer, 2020, Volume: 1873, Issue:2

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Transformation, Neoplastic; Cholesterol; Clinical Trials as Topic; Disease Progression; Geranyltranstransferase; Humans; Hydroxymethylglutaryl CoA Reductases; Metabolic Networks and Pathways; Mevalonic Acid; Neoplasms; Protein Processing, Post-Translational; rho GTP-Binding Proteins; Sterol Regulatory Element Binding Proteins; Treatment Outcome

2020
Benefits of Bisphosphonate Therapy: Beyond the Skeleton.
    Current osteoporosis reports, 2020, Volume: 18, Issue:5

    Topics: Atherosclerosis; Bone Density Conservation Agents; Breast Neoplasms; Colorectal Neoplasms; Diphosphonates; Disease Progression; Endothelial Cells; Humans; Macrophages; Mevalonic Acid; Monocytes; Mortality; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protective Factors; Vascular Calcification

2020
Mitochondrial Acetyl-CoA Synthetase 3 is Biosignature of Gastric Cancer Progression.
    Cancer medicine, 2018, Volume: 7, Issue:4

    Topics: Acetate-CoA Ligase; Apoptosis; Biomarkers; CCAAT-Enhancer-Binding Proteins; Cholesterol; Databases, Genetic; Disease Progression; Energy Metabolism; Humans; Metabolic Networks and Pathways; Mevalonic Acid; Mitochondria; Models, Biological; Neoplasm Staging; Prognosis; Proportional Hazards Models; Stomach Neoplasms; Stress, Physiological

2018
Could drugs inhibiting the mevalonate pathway also target cancer stem cells?
    Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2016, Volume: 25

    Topics: Animals; Antineoplastic Agents; Disease Progression; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Molecular Targeted Therapy; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Proto-Oncogene Mas

2016
Regulatory properties of statins and rho gtpases prenylation inhibitiors to stimulate melanoma immunogenicity and promote anti-melanoma immune response.
    International journal of cancer, 2017, 02-15, Volume: 140, Issue:4

    Topics: Adaptive Immunity; Adjuvants, Immunologic; Animals; Antineoplastic Agents; Disease Progression; Enzyme Activation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunity, Innate; Melanoma; Melanoma, Experimental; Mevalonic Acid; Mice; Molecular Targeted Therapy; Neoplasm Proteins; Protein Prenylation; rho GTP-Binding Proteins; Signal Transduction

2017
Statins and prostate cancer prevention: where we are now, and future directions.
    Nature clinical practice. Urology, 2008, Volume: 5, Issue:7

    Topics: Animals; Apoptosis; Cardiovascular Diseases; Cell Cycle; Comorbidity; Disease Progression; GTPase-Activating Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Meta-Analysis as Topic; Mevalonic Acid; Prostate-Specific Antigen; Prostatic Neoplasms; ras GTPase-Activating Proteins

2008

Other Studies

9 other study(ies) available for mevalonic acid and Disease Exacerbation

ArticleYear
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.
    The Journal of experimental medicine, 2020, 09-07, Volume: 217, Issue:9

    Topics: Animals; Cell Line, Tumor; Cholesterol; Disease Progression; Humans; Loss of Heterozygosity; Mevalonic Acid; Mice, Inbred C57BL; Models, Biological; Pancreatic Neoplasms; Sterol O-Acyltransferase; Tumor Suppressor Protein p53

2020
Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway.
    Cells, 2020, 07-31, Volume: 9, Issue:8

    Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Movement; Cholesterol; Disease Progression; Drug Resistance; ERRalpha Estrogen-Related Receptor; Female; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Mevalonic Acid; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Prognosis; Receptors, Estrogen; Signal Transduction

2020
Phenotypic diversity, disease progression, and pathogenicity of MVK missense variants in mevalonic aciduria.
    Journal of inherited metabolic disease, 2021, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Disease Progression; Female; Humans; Male; Mevalonate Kinase Deficiency; Mevalonic Acid; Mutation, Missense; Phosphotransferases (Alcohol Group Acceptor); Young Adult

2021
A Method for Detection of Cholesterol Synthesis in the Placenta during Exacerbation of Cytomegalovirus Infection.
    Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1

    Topics: Adult; Case-Control Studies; Cholesterol; Cytomegalovirus Infections; Disease Progression; Female; Gonadal Steroid Hormones; Humans; Hydroxysteroid Dehydrogenases; Mevalonic Acid; Placenta; Placental Insufficiency; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Squalene

2015
Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?
    World journal of urology, 2013, Volume: 31, Issue:2

    Topics: Aged; Disease Progression; Disease-Free Survival; Geranyltranstransferase; Humans; Male; Mevalonic Acid; Middle Aged; Multivariate Analysis; Neoplasm Grading; Neoplasm Staging; Prognosis; Prostate; Prostatic Neoplasms; Risk Factors; Tissue Array Analysis

2013
Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Animals; Antioxidants; Cytokines; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Enzyme Activation; Gene Expression Regulation; Humans; Inflammation Mediators; Male; Mevalonic Acid; Mice; Mice, Inbred C57BL; Microglia; Motor Activity; Neuroglia; NF-kappa B; Nitric Oxide Synthase Type II; Oncogene Protein p21(ras); Parkinson Disease; Phenylbutyrates; Reactive Oxygen Species

2012
An intestinal obstruction in an eight-month-old child suffering from mevalonic aciduria.
    Acta paediatrica (Oslo, Norway : 1992), 2002, Volume: 91, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Disease Progression; Fatal Outcome; Humans; Ileal Diseases; Infant; Intestinal Obstruction; Jejunal Diseases; Laparotomy; Male; Mevalonic Acid; Severity of Illness Index

2002
Simvastatin protection against acute immune-mediated glomerulonephritis in mice.
    Kidney international, 2006, Volume: 69, Issue:3

    Topics: Acute Disease; Animals; Blood Urea Nitrogen; Disease Progression; Dose-Response Relationship, Drug; Female; Glomerulonephritis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Mevalonic Acid; Mice; Mice, Inbred C57BL; Proteinuria; Severity of Illness Index; Simvastatin

2006
Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:6

    Topics: Apoptosis; Disease Progression; GTP Phosphohydrolases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Multiple Myeloma

2007