mevalonic acid and Cardiovascular Diseases

mevalonic acid has been researched along with Cardiovascular Diseases in 17 studies

*Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. [MeSH]

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's6 (35.29)29.6817
2010's7 (41.18)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Britza, SM; Byard, RW; Farrington, R; Musgrave, IF; Zechner, J1
Anderson, KA; Backos, DS; Crown, SB; Grimsrud, PA; Hirschey, MD; Ilkayeva, OR; Kulkarni, RA; Meier, JL; Stevens, RD; Thompson, JW; Trub, AG; Wagner, GR; Zhang, GF1
Basson, AK; Dludla, PV; Mabhida, SE; Mazibuko-Mbeje, SE; Mthembu, SXH; Muller, CJF; Nkambule, BB; Nyambuya, TM; Orlando, P; Silvestri, S; Tiano, L; Ziqubu, K1
Casal-Dominguez, M; Mammen, AL; Pinal-Fernandez, I1
Norata, GD1
Ande, SR; Freed, DH; Ghavami, S; Hashemi, M; Moghadam, AR; Post, M; Sharma, P; Shojaei, S; Wiechec, E; Yeganeh, B; Zeki, AA1
Ande, SR; Chen, QM; Hashemi, M; Hoshyar, R; Naderi, M; Solomon, C; Zuse, A1
Lahtela, J; Murtola, TJ; Syvälä, H; Tammela, TLj; Visakorpi, T1
Ishibashi, T1
Keizer, HG1
DiNicolantonio, JJ1
Poirier, J1
Laufs, U; Liao, JK1
Gotto, AM; Vaughan, CJ1
Bravo, L; Gupta, J; McAnally, JA; Mo, H; Sodhani, S1
Duleba, AJ; Kodaman, PH1
Elson, CE1

Reviews

13 review(s) available for mevalonic acid and Cardiovascular Diseases

ArticleYear
Flavonoid-statin interactions causing myopathy and the possible significance of OATP transport, CYP450 metabolism and mevalonate synthesis.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Cardiovascular Diseases; Cytochrome P-450 Enzyme System; Drug Interactions; Flavonoids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Mevalonic Acid; Muscular Diseases; Myotoxicity; Organic Anion Transporters; Risk Factors

2022
Impact of dyslipidemia in the development of cardiovascular complications: Delineating the potential therapeutic role of coenzyme Q
    Biochimie, 2023, Volume: 204

    Topics: Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; Dyslipidemias; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Ubiquinone

2023
Statins: pros and cons.
    Medicina clinica, 2018, 05-23, Volume: 150, Issue:10

    Topics: Anti-Inflammatory Agents; Anticholesteremic Agents; Atherosclerosis; Blood Coagulation; Cardiovascular Diseases; Cerebral Hemorrhage; Cholesterol; Diabetes Mellitus, Type 2; Endothelium, Vascular; Fibrinolytic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunologic Factors; Inflammation; Mevalonic Acid; Musculoskeletal Diseases

2018
Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.
    Pharmacology & therapeutics, 2014, Volume: 143, Issue:1

    Topics: Alkyl and Aryl Transferases; Animals; Cardiovascular Diseases; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Diseases; Mevalonic Acid; Neoplasms; Pulmonary Disease, Chronic Obstructive; rho GTP-Binding Proteins; rho-Associated Kinases

2014
Mevalonate Cascade and its Regulation in Cholesterol Metabolism in Different Tissues in Health and Disease.
    Current molecular pharmacology, 2017, Volume: 10, Issue:1

    Topics: Acyl Coenzyme A; Animals; Cardiovascular Diseases; Cholesterol; GTP Phosphohydrolases; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infections; Mevalonic Acid; Neoplasms; Polyisoprenyl Phosphates; Sesquiterpenes; Signal Transduction

2017
Statins and prostate cancer prevention: where we are now, and future directions.
    Nature clinical practice. Urology, 2008, Volume: 5, Issue:7

    Topics: Animals; Apoptosis; Cardiovascular Diseases; Cell Cycle; Comorbidity; Disease Progression; GTPase-Activating Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Meta-Analysis as Topic; Mevalonic Acid; Prostate-Specific Antigen; Prostatic Neoplasms; ras GTPase-Activating Proteins

2008
[Anti-atherosclerotic and anti-inflammatory effects of statin on cardiovascular disease and their mechanisms].
    Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69, Issue:1

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mevalonic Acid; Monomeric GTP-Binding Proteins; Plaque, Atherosclerotic; Pravastatin; Primary Prevention; Randomized Controlled Trials as Topic; Secondary Prevention

2011
CoQ10 and L-carnitine for statin myalgia?
    Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:10

    Topics: Cardiovascular Diseases; Carnitine; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Mitochondria, Muscle; Musculoskeletal Pain; Ubiquinone

2012
Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease.
    Trends in molecular medicine, 2003, Volume: 9, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Brain; Cardiovascular Diseases; Central Nervous System; Cholesterol; Humans; Mevalonic Acid; Models, Biological; Models, Chemical; Phospholipids

2003
Isoprenoid metabolism and the pleiotropic effects of statins.
    Current atherosclerosis reports, 2003, Volume: 5, Issue:5

    Topics: Cardiovascular Diseases; Cardiovascular System; Evaluation Studies as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Mevalonic Acid; Polyisoprenyl Phosphates; Time Factors

2003
Update on statins: 2003.
    Circulation, 2004, Aug-17, Volume: 110, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiovascular Diseases; Cholesterol, LDL; Creatine Kinase; Creatine Kinase, MM Form; Drug Interactions; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inactivation, Metabolic; Isoenzymes; Male; Mevalonic Acid; Middle Aged; Models, Biological; Muscular Diseases; Prospective Studies; Protein Prenylation; Randomized Controlled Trials as Topic; Structure-Activity Relationship

2004
Statins in the treatment of polycystic ovary syndrome.
    Seminars in reproductive medicine, 2008, Volume: 26, Issue:1

    Topics: Cardiovascular Diseases; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Models, Biological; Ovary; Oxidative Stress; Polycystic Ovary Syndrome; Signal Transduction

2008
Suppression of mevalonate pathway activities by dietary isoprenoids: protective roles in cancer and cardiovascular disease.
    The Journal of nutrition, 1995, Volume: 125, Issue:6 Suppl

    Topics: Animals; Cardiovascular Diseases; Diet; Humans; Hydroxymethylglutaryl-CoA Synthase; Mevalonic Acid; Neoplasms; Neoplasms, Experimental; Terpenes

1995

Other Studies

4 other study(ies) available for mevalonic acid and Cardiovascular Diseases

ArticleYear
Statin therapy inhibits fatty acid synthase via dynamic protein modifications.
    Nature communications, 2022, 05-10, Volume: 13, Issue:1

    Topics: Cardiovascular Diseases; Cholesterol; Fatty Acid Synthases; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid

2022
Trained immunity and cardiovascular disease: is it time for translation to humans?
    Cardiovascular research, 2018, 05-01, Volume: 114, Issue:6

    Topics: Cardiovascular Diseases; Humans; Immunity, Innate; Mevalonic Acid; Monocytes

2018
The "Mevalonate hypothesis": a cholesterol-independent alternative for the etiology of atherosclerosis.
    Lipids in health and disease, 2012, Nov-05, Volume: 11

    Topics: Atherosclerosis; Biomarkers; Cardiovascular Diseases; Cholesterol; Free Radicals; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Metabolic Networks and Pathways; Mevalonic Acid; Models, Cardiovascular

2012
Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo.
    Experimental biology and medicine (Maywood, N.J.), 2007, Volume: 232, Issue:4

    Topics: Animals; Antioxidants; Cardiovascular Diseases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Neoplasm Proteins; Neoplasms; Terpenes; Tocotrienols

2007