mevalonic acid has been researched along with Cancer of Prostate in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 14 (51.85) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Freedland, SJ; Hamilton, RJ; Longo, J; Penn, LZ | 1 |
| Chen, EX; Fleshner, NE; Hamilton, RJ; Longo, J; Masoomian, M; Mullen, PJ; Penn, LZ; Sweet, JM; van der Kwast, TH; van Leeuwen, JE; Wang, Y; Woon, DTS; Yu, R | 1 |
| Bonneville, M; Catros, V; Léger, A; Robard, M; Santolaria, T; Scotet, E | 1 |
| Arra, C; Bruzzese, F; Budillon, A; Caraglia, M; Chianese, MI; Ciardiello, C; Di Gennaro, E; Franco, R; Leone, A; Luciano, A; Milone, MR; Pucci, B; Rocco, M; Santini, D | 1 |
| Arkko, S; Benzaïd, I; Clézardin, P; Määttä, JA; Mönkkönen, H; Mönkkönen, J; Räikkönen, J; Zlatev, HP | 1 |
| Alizadeh, J; Barazeh, M; Kavousipour, S; Mokarram, P; Razban, V; Solomon, C | 1 |
| Bishop, KS; Denny, WA; Ferguson, LR; Lin, Z; Marlow, G; Murray, P; Sutherland, H | 1 |
| Aprikian, AG; Magliocco, AM; Martinez-Arguelles, DB; Papadopoulos, V; Sakai, M | 1 |
| Chiarugi, P; Comito, G; Giannoni, E; Lanciotti, M; Morandi, A; Pons Segura, C; Serni, S; Taddei, ML | 1 |
| Lahtela, J; Murtola, TJ; Syvälä, H; Tammela, TLj; Visakorpi, T | 1 |
| Heber, D; Hong, MY; Seeram, NP; Zhang, Y | 1 |
| Engelmann, U; Epplen, R; Heidenreich, A; Ohlmann, CH; Stöckle, M | 1 |
| Hirano, K; Iguchi, K; Tatsuda, Y; Usui, S | 1 |
| Freiser, H; Jiang, Q; Jiang, Z; Kim, CY; Li, G; Rao, X; Zhang, Q | 1 |
| Bläuer, M; Murtola, TJ; Pennanen, P; Solakivi, T; Syvälä, H; Tammela, TL; Ylikomi, T | 1 |
| Aufderklamm, S; Gakis, G; Gerber, V; Hennenlotter, J; Knapp, J; Kühs, U; Merseburger, A; Schwentner, C; Stenzl, A; Todenhöfer, T; Vogel, U | 1 |
| Iguchi, K | 1 |
| Clarke, IA; Colston, KW; Kirby, RS; Oades, GM; Senaratne, SG | 1 |
| Andela, VB | 1 |
| Coleman, RE; Evans, CA; Holen, I; Neville-Webbe, HL; Rostami-Hodjegan, A | 1 |
| Chellaiah, MA; Desai, B; Rogers, MJ | 1 |
| Llorente, A; Sandvig, K; van Deurs, B | 1 |
| Bertoldo, F; Dalle Carbonare, L; Donatelli, L; Lo Cascio, V; Valenti, MT | 1 |
| Miller, AC; Samid, D | 1 |
| Foster, BA; Ghosh, PM; Ghosh-Choudhury, N; Greenberg, NM; Kreisberg, JI; Mott, GE; Moyer, ML; Thomas, CA | 1 |
| Fawcett, TW; Gorospe, M; Holbrook, NJ; Hudgins, WR; Shack, S | 1 |
| Härkönen, PL; Lakkakorpi, PT; Väänänen, HK; Virtanen, SS | 1 |
4 review(s) available for mevalonic acid and Cancer of Prostate
| Article | Year |
|---|---|
Statins and prostate cancer-hype or hope? The biological perspective.
Topics: Antineoplastic Agents; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mevalonic Acid; Prostatic Neoplasms | 2022 |
Interconnection of Estrogen/Testosterone Metabolism and Mevalonate Pathway in Breast and Prostate Cancers.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholesterol; Estradiol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mevalonic Acid; Prostatic Neoplasms; Signal Transduction; Testosterone | 2017 |
Statins and prostate cancer prevention: where we are now, and future directions.
Topics: Animals; Apoptosis; Cardiovascular Diseases; Cell Cycle; Comorbidity; Disease Progression; GTPase-Activating Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Meta-Analysis as Topic; Mevalonic Acid; Prostate-Specific Antigen; Prostatic Neoplasms; ras GTPase-Activating Proteins | 2008 |
[Effect of bisphosphonates on anticancer activity in prostate cancer cells].
Topics: Antineoplastic Agents; Apoptosis; Diphosphonates; Humans; Male; Mevalonic Acid; Neoplasm Metastasis; Prostatic Neoplasms; Tumor Cells, Cultured | 2012 |
23 other study(ies) available for mevalonic acid and Cancer of Prostate
| Article | Year |
|---|---|
An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dipyridamole; Drug Repositioning; Fluvastatin; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Male; Mevalonic Acid; Mice; Mice, Inbred NOD; Mice, SCID; Prostatic Neoplasms; Sterol Regulatory Element Binding Protein 2; Sterols; Xenograft Model Antitumor Assays | 2019 |
Repeated systemic administrations of both aminobisphosphonates and human Vγ9Vδ2 T cells efficiently control tumor development in vivo.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Diphosphonates; Drug Administration Schedule; Humans; Immunologic Deficiency Syndromes; Immunotherapy, Adoptive; Lymphocyte Activation; Male; Mevalonic Acid; Mice; Mice, Mutant Strains; Mice, SCID; Pamidronate; Prostatic Neoplasms; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Xenograft Model Antitumor Assays | 2013 |
Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.
Topics: Animals; Antineoplastic Agents; Apoptosis; Diphosphonates; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Humans; Hydroxamic Acids; Imidazoles; Indoles; Male; Mevalonic Acid; Mice; Mice, Nude; Models, Biological; Multiple Myeloma; p38 Mitogen-Activated Protein Kinases; Panobinostat; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Xenograft Model Antitumor Assays; Zoledronic Acid | 2013 |
Upregulation of the mevalonate pathway by cholesterol depletion abolishes tolerance to N-bisphosphonate induced Vγ9Vδ2 T cell cytotoxicity in PC-3 prostate cancer cells.
Topics: Cell Line, Tumor; Cholesterol; Cytotoxicity, Immunologic; Diphosphonates; Humans; Imidazoles; Male; Mevalonic Acid; Prostatic Neoplasms; Receptors, Antigen, T-Cell, gamma-delta; Signal Transduction; T-Lymphocytes; Up-Regulation; Zoledronic Acid | 2015 |
A quinazoline-based HDAC inhibitor affects gene expression pathways involved in cholesterol biosynthesis and mevalonate in prostate cancer cells.
Topics: Cell Line, Tumor; Cholesterol; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Inhibitory Concentration 50; Male; Mevalonic Acid; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Quinazolines; Reproducibility of Results; Signal Transduction | 2016 |
De novo steroid biosynthesis in human prostate cell lines and biopsies.
Topics: Aged; Androgens; Cell Culture Techniques; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Male; Mevalonic Acid; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, GABA; Steroid 17-alpha-Hydroxylase | 2016 |
Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts.
Topics: Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Movement; Diphosphonates; Humans; Imidazoles; Macrophage Activation; Macrophages; Male; Mevalonic Acid; Neoplasm Metastasis; Neovascularization, Pathologic; Phenotype; Prostatic Neoplasms; rhoA GTP-Binding Protein; Stromal Cells; Tumor Microenvironment; Zoledronic Acid | 2017 |
Chinese red yeast rice versus lovastatin effects on prostate cancer cells with and without androgen receptor overexpression.
Topics: Androgens; Anticholesteremic Agents; Apoptosis; Biological Products; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Monascus; Prostate; Prostatic Neoplasms; Receptors, Androgen; Sterol Regulatory Element Binding Protein 2 | 2008 |
Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Diphosphonates; Docetaxel; Drug Synergism; Farnesol; Humans; Ibandronic Acid; Male; Mevalonic Acid; Prenylation; Prostatic Neoplasms; Signal Transduction; Taxoids | 2011 |
Pamidronate inhibits antiapoptotic bcl-2 expression through inhibition of the mevalonate pathway in prostate cancer PC-3 cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Diphosphonates; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; Mevalonic Acid; Pamidronate; Prostatic Neoplasms; Protein Prenylation; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; Signal Transduction | 2010 |
Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Ceramides; Chromans; Humans; Intracellular Space; Male; Mevalonic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Sphingosine; Tumor Burden; Vitamin E | 2012 |
Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL.
Topics: Apoptosis; Cell Cycle; Cell Line; Cell Line, Tumor; Cellular Senescence; Cholesterol, LDL; Dose-Response Relationship, Drug; Epithelial Cells; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mevalonic Acid; Prostate; Prostatic Neoplasms; Pyrimidines; Rosuvastatin Calcium; Simvastatin; Sulfonamides | 2011 |
Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression?
Topics: Aged; Disease Progression; Disease-Free Survival; Geranyltranstransferase; Humans; Male; Mevalonic Acid; Middle Aged; Multivariate Analysis; Neoplasm Grading; Neoplasm Staging; Prognosis; Prostate; Prostatic Neoplasms; Risk Factors; Tissue Array Analysis | 2013 |
Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Membrane; Cell Survival; Diphosphonates; DNA Fragmentation; Humans; Imidazoles; Male; Mevalonic Acid; Pamidronate; Prostatic Neoplasms; Protein Prenylation; ras Proteins; Zoledronic Acid | 2003 |
Correspondence Re S. S. Virtanen et al., Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway. Cancer Res 2002;62:2708-14. Re K. Sawada et al., Alendronate inhibits lysophosphatidic acid-induced migration of huma
Topics: Alendronate; Humans; Male; Mevalonic Acid; Neoplasm Invasiveness; Prostatic Neoplasms | 2004 |
Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Breast Neoplasms; Diphosphonates; Diterpenes; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imidazoles; Male; Mevalonic Acid; Prostatic Neoplasms; Time Factors; Tumor Cells, Cultured; Zoledronic Acid | 2005 |
Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells.
Topics: Adenocarcinoma; Bone Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Diphosphonates; Enzyme Activation; Giant Cells; Humans; Hyaluronan Receptors; Integrin alphaVbeta3; Male; Matrix Metalloproteinase 9; Mevalonic Acid; Mutant Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Osteopontin; Prostatic Neoplasms; Protein Prenylation; RANK Ligand; Recombinant Fusion Proteins; rho GTP-Binding Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction | 2007 |
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells.
Topics: beta-Cyclodextrins; Cell Line, Tumor; Cholesterol; Endocytosis; Humans; Lovastatin; Lysosomes; Male; Mevalonic Acid; Neoplasm Proteins; Prostatic Neoplasms; Secretory Vesicles | 2007 |
The effects on hTERT gene expression is an additional mechanism of amino-bisphosphonates in prostatic cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Diphosphonates; Down-Regulation; Drug Delivery Systems; Farnesyltranstransferase; Gene Expression Regulation, Neoplastic; Humans; Male; Mevalonic Acid; Prostatic Neoplasms; Telomerase | 2008 |
Tumor radiosensitization based on the use of inhibitors of the mevalonate pathway of cholesterol synthesis.
Topics: Adenocarcinoma; Brain Neoplasms; Breast Neoplasms; Cell Survival; Cholesterol; Cobalt Radioisotopes; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexenes; Dose-Response Relationship, Radiation; Female; Fibrosarcoma; Gamma Rays; Genes, ras; Glioblastoma; Humans; Limonene; Lung Neoplasms; Male; Mevalonic Acid; Prostatic Neoplasms; Radiation-Sensitizing Agents; Terpenes; Tumor Cells, Cultured | 1997 |
Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line.
Topics: Actin Cytoskeleton; Adenocarcinoma; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Division; Cell Size; Diterpenes; Drug Interactions; Enzyme Activation; Farnesol; G1 Phase; Genes, ras; GTP-Binding Proteins; Guanosine Triphosphate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Mice; Mice, Transgenic; Polyisoprenyl Phosphates; Prostatic Neoplasms; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); rac GTP-Binding Proteins; rhoA GTP-Binding Protein; Sesquiterpenes; Tumor Cells, Cultured | 1999 |
Activation of the cholesterol pathway and Ras maturation in response to stress.
Topics: Adenocarcinoma; Calcium-Calmodulin-Dependent Protein Kinases; Cholesterol; Diterpenes; Farnesol; Genes, ras; Heat-Shock Response; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Lovastatin; Male; Mevalonic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Prenylation; ras Proteins; Sterols; Stress, Physiological | 1999 |
Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
Topics: Alendronate; Antimetabolites; Bone Neoplasms; Cell Movement; Clodronic Acid; Dose-Response Relationship, Drug; Humans; Male; Mevalonic Acid; Neoplasm Invasiveness; Prostatic Neoplasms; Tumor Cells, Cultured | 2002 |