mevalonic acid and Cancer of Liver

Topics: Animals; Carcinoma, Hepatocellular; Chromatography, Liquid; Diterpenes; Fatty Acids; Humans; Liver Neoplasms; Male; Mammals; Mevalonic Acid; Monoamine Oxidase; Rats; Retinoids; Tandem Mass Spectrometry

Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Mevalonic Acid; Terpenes

Topics: Colorectal Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Mevalonic Acid; Pancreatic Neoplasms; Stomach Neoplasms

Topics: Aging; Animals; Antioxidants; Diet; Dolichols; Half-Life; Humans; Lipid Metabolism; Liver; Liver Neoplasms; Mevalonic Acid; Oxidative Stress; Ubiquinone

Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

Topics: Carcinoma, Hepatocellular; Gynostemma; Humans; Hydroxymethylglutaryl-CoA Synthase; Liver Neoplasms; Mevalonic Acid

Topics: Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; HEK293 Cells; Hep G2 Cells; Humans; Liver Neoplasms; Mevalonic Acid; Neoplasm Proteins

Topics: Apoptosis; Bone Neoplasms; Carcinoma, Hepatocellular; Cell Growth Processes; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Survival; Cytosol; Depression, Chemical; Diphosphonates; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; Mevalonic Acid; Mitogen-Activated Protein Kinases; Signal Transduction; Zoledronic Acid

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Adhesion; Cell Communication; Cell Proliferation; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinical; Endothelial Cells; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrins; Liver Neoplasms; Mevalonic Acid; rho-Associated Kinases; Simvastatin

Topics: Acute-Phase Reaction; Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Interleukin-1; Interleukin-6; Liver Neoplasms; Lovastatin; Mevalonic Acid; Plasminogen Activator Inhibitor 1; RNA, Messenger; Up-Regulation

Topics: Carcinoma, Hepatocellular; Cell Division; Cholesterol; Enzyme Inhibitors; Ethanol; Humans; Hydroxymethylglutaryl CoA Reductases; Isotope Labeling; Liver Neoplasms; Mevalonic Acid; Tumor Cells, Cultured

Topics: Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lipid Metabolism; Liver Neoplasms; Mevalonic Acid; Quinolines; Rats

Topics: 2-Acetylaminofluorene; Alkyl and Aryl Transferases; Animals; Dimethylallyltranstransferase; Dolichols; Enzyme Induction; Farnesyltranstransferase; Hydroxymethylglutaryl CoA Reductases; Liver; Liver Neoplasms; Male; Mevalonic Acid; Precancerous Conditions; Rats; Rats, Wistar; Transferases

Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cholesterol; Cyclohexenes; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Interactions; Humans; Kinetics; Limonene; Liver Neoplasms; Mevalonic Acid; Pravastatin; Protein Prenylation; Proto-Oncogene Proteins p21(ras); Terpenes; Tumor Cells, Cultured

Topics: Acetates; Acetic Acid; Androstenes; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chickens; CHO Cells; Cholesterol; Chromans; Cricetinae; Gene Expression Regulation, Enzymologic; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Ketoconazole; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Suppression, Genetic; Tritium; Tumor Cells, Cultured; Vitamin E

Topics: Base Sequence; Cell Division; Cell Line; Cell Membrane; Colonic Neoplasms; DNA Primers; DNA, Neoplasm; Dolichol Phosphates; Enzyme Inhibitors; Gene Expression; Glycosylation; Growth Substances; Hepatoblastoma; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin-Like Growth Factor I; Kinetics; Liver Neoplasms; Lovastatin; Melanoma; Mevalonic Acid; Models, Biological; Molecular Sequence Data; Oligonucleotides, Antisense; Protein Processing, Post-Translational; Receptor, IGF Type 1; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

Topics: Animals; Butyrates; Butyric Acid; Cell Division; Colorectal Neoplasms; Liver Neoplasms; Mevalonic Acid; Mice; Mice, Inbred BALB C; Thymidine; Tritium; Tumor Cells, Cultured

Topics: Anticholesteremic Agents; Carboxy-Lyases; Carcinoma, Hepatocellular; Cholesterol; Fatty Acids; Homeostasis; Humans; Kinetics; Liver Neoplasms; Lovastatin; Mevalonic Acid; Structure-Activity Relationship; Tumor Cells, Cultured

Topics: Arachidonic Acid; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Cholesterol; Enzyme Inhibitors; Ethanol; Fatty Acids, Unsaturated; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Linoleic Acid; Linoleic Acids; Liver Neoplasms; Lovastatin; Mevalonic Acid; Monocytes; Neuroblastoma; Simvastatin; Tumor Cells, Cultured

Topics: Autoradiography; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cysteine; Dolichols; Hepatoblastoma; Humans; Liver Neoplasms; Melanoma; Mevalonic Acid; Neoplasm Proteins; Peptide Fragments; Protein Prenylation; Sulfur Radioisotopes; Tritium; Tumor Cells, Cultured

Topics: Carcinoma, Hepatocellular; Dactinomycin; ErbB Receptors; Gemfibrozil; Gene Expression Regulation, Neoplastic; Genes, Reporter; Half-Life; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liver Neoplasms; Mevalonic Acid; Neoplasm Proteins; Pravastatin; Promoter Regions, Genetic; Receptors, LDL; RNA, Messenger; RNA, Neoplasm; Transfection; Tumor Cells, Cultured; Up-Regulation

Topics: 3T3 Cells; Adipocytes; Animals; Anticholesteremic Agents; Apolipoproteins E; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Hepatocellular; Cell Differentiation; Cells, Cultured; Cholesterol; Diet, Atherogenic; Dimerization; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Hydrocarbons, Fluorinated; Hydroxycholesterols; Ligands; Lipids; Liver Neoplasms; Liver X Receptors; Lovastatin; Macrophages, Peritoneal; Male; Mevalonic Acid; Mice; Mice, Knockout; Organic Chemicals; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured

Topics: Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Diterpenes; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mevalonic Acid; Neoplasm Proteins; Oligopeptides; Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Cells, Cultured; Ursodeoxycholic Acid; X-Linked Inhibitor of Apoptosis Protein

Topics: Acetates; Adult; Alkaline Phosphatase; Bilirubin; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cholestasis; Cholesterol; Cholesterol, Dietary; Feedback; Humans; Hypercholesterolemia; Liver; Liver Neoplasms; Male; Mevalonic Acid; Middle Aged

Topics: Acetates; Anticholesteremic Agents; Benzylamines; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cycloheximide; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; Nucleic Acid Hybridization; Oxygenases; RNA, Neoplasm; Simvastatin; Squalene Monooxygenase; Thiophenes

Topics: Carcinoma, Hepatocellular; Cell Line, Transformed; Chromatography, High Pressure Liquid; Dolichols; Humans; Leukemia; Leukocytes, Mononuclear; Liver Neoplasms; Lymphocytes; Mevalonic Acid; Tumor Cells, Cultured

Topics: Carcinoma, Hepatocellular; Cell-Free System; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Liver Neoplasms; Lovastatin; Mevalonic Acid; Oxidoreductases; Receptors, LDL; Sterol 14-Demethylase; Sterols; Tumor Cells, Cultured

Topics: Binding, Competitive; Carcinoma, Hepatocellular; Cholesterol; Detergents; Enzyme Induction; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Liver; Liver Neoplasms; Lovastatin; Mevalonic Acid; Microsomes, Liver; Octoxynol; Oxygenases; Polyethylene Glycols; Simvastatin; Squalene Monooxygenase; Tumor Cells, Cultured

Topics: Carcinoma, Hepatocellular; Cell Line; Cholesterol; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lipase; Liver Neoplasms; Lovastatin; Mevalonic Acid; RNA Probes; RNA, Messenger; Transcription, Genetic

Topics: Androstenes; Carcinoma, Hepatocellular; Cholesterol; Farnesyl-Diphosphate Farnesyltransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intramolecular Transferases; Isomerases; Lipoproteins, HDL; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; Oxidoreductases; Sterols; Tumor Cells, Cultured

Topics: Carcinoma, Hepatocellular; DNA, Neoplasm; Gene Expression Regulation; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Liver Neoplasms; Lovastatin; Mevalonic Acid; Oxo-Acid-Lyases; Receptors, LDL; RNA, Messenger; Tumor Cells, Cultured

Topics: Carcinoma, Hepatocellular; Cytidine Triphosphate; Cytosine Nucleotides; Dolichol Phosphates; Dolichols; Glycosylation; Humans; Liver Neoplasms; Mevalonic Acid; Microsomes, Liver; Middle Aged; Phosphoric Monoester Hydrolases; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Polyisoprenyl Phosphates

Topics: Acetates; Acetic Acid; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Cyclic AMP; Humans; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Mevalonic Acid; Receptors, LDL; Theophylline

Topics: Androstenes; Anticholesteremic Agents; Carcinoma, Hepatocellular; Cell Line; Enzyme Activation; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Immunoblotting; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Mevalonic Acid; RNA, Messenger; Tumor Cells, Cultured

Topics: Acetates; Apolipoproteins B; Carcinoma, Hepatocellular; Cell Line; Humans; Kinetics; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Liver Neoplasms; Methionine; Mevalonic Acid; Oleic Acid; Oleic Acids; Phospholipids; Serum Albumin, Bovine; Triglycerides

Topics: Androstenes; Animals; Anticholesteremic Agents; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Imidoesters; Lipid Metabolism; Liver Neoplasms; Lovastatin; Mevalonic Acid; Naphthalenes; Triparanol

Topics: Acetates; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cholesterol; Dietary Fats; Fatty Acids; Lipids; Liver; Liver Neoplasms; Mevalonic Acid; Neoplasms, Experimental; Oxygen Consumption; Rats

Topics: Acetates; Alcohol Oxidoreductases; Animals; Carcinoma, Hepatocellular; Cholesterol; Coenzyme A; Diet; Liver; Liver Neoplasms; Male; Mevalonic Acid; Mice; Microsomes, Liver; Neoplasm Transplantation; Neoplasms, Experimental; Sterols; Surface-Active Agents

Topics: Aflatoxins; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cholesterol; Feedback; Glycolysis; Guinea Pigs; Humans; Leukemia, Experimental; Liver; Liver Neoplasms; Mevalonic Acid; Mice; Neoplasms, Experimental; Rats; Salmonidae

Topics: Alcohol Oxidoreductases; Animals; Carcinoma, Hepatocellular; Cholesterol; Cholestyramine Resin; Circadian Rhythm; Liver Neoplasms; Male; Mevalonic Acid; Microsomes, Liver; Neoplasm Transplantation; Neoplasms, Experimental; Rats

Topics: Blood; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Count; Cell Line; Cholesterol; Culture Media; Dialysis; Fatty Acids, Nonesterified; Feedback; Fructose; Glucose; Glycerol; Glycolysis; Lipid Metabolism; Lipids; Lipoproteins; Liver Neoplasms; Mevalonic Acid; Phospholipids; Triglycerides; Tritium; Water

Topics: Acetamides; Acetates; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cholesterol; Cholesterol, Dietary; Culture Media; Esters; Fluorenes; Hyperplasia; Hypertrophy; Liver; Liver Neoplasms; Male; Mevalonic Acid; Microsomes, Liver; Mitochondria, Liver; Precancerous Conditions; Rats; Time Factors; Tritium

Topics: Acetyltransferases; Acylation; Animals; Carcinoma, Hepatocellular; Cholesterol; Esters; Fatty Acids; Lipoproteins; Lipoproteins, LDL; Liver; Liver Neoplasms; Male; Mevalonic Acid; Neoplasms, Experimental; Rats; Time Factors; Tritium

Topics: Acetates; Alcohol Oxidoreductases; Allosteric Regulation; Animals; Blood; Caprylates; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cholesterol; Culture Media; Feedback; Fibroblasts; Glutarates; Humans; In Vitro Techniques; Kinetics; Lipoproteins; Liver; Liver Neoplasms; Male; Mevalonic Acid; Microsomes, Liver; Rats; Temperature

Topics: Acetates; Animals; Bile Acids and Salts; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cholesterol, Dietary; Chromatography, Gas; In Vitro Techniques; Liver; Liver Neoplasms; Mevalonic Acid; Neoplasms, Experimental; Rats

Topics: Acetates; Animals; Anticholesteremic Agents; Carcinoma, Hepatocellular; Cholesterol; Fatty Acids; Liver; Liver Neoplasms; Male; Mevalonic Acid; Neoplasm Transplantation; Neoplasms, Experimental; Onium Compounds; Organophosphorus Compounds; Piperidines; Plant Growth Regulators; Quaternary Ammonium Compounds; Rats

Topics: Alcohol Oxidoreductases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Chromatography, Gel; Drug Stability; Electrophoresis, Polyacrylamide Gel; Glutarates; Hot Temperature; Kinetics; Liver Neoplasms; Membranes; Mevalonic Acid; Microsomes, Liver; Rats; Rats, Inbred Strains; Solubility; Temperature; Time Factors; Tritium

Topics: Alcohol Oxidoreductases; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cattle; Cell Line; Chromatography, Thin Layer; Coenzyme A; Culture Media; Cycloheximide; Dactinomycin; Enzyme Activation; Glutarates; Half-Life; Kinetics; Lipoproteins; Liver Neoplasms; Mevalonic Acid; Microsomes; Neoplasms, Experimental; Rats; Time Factors; Tritium; Ultracentrifugation