mevalonic acid and Brain Neoplasms

mevalonic acid has been researched along with Brain Neoplasms in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's3 (23.08)18.2507
2000's0 (0.00)29.6817
2010's5 (38.46)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Ahmad, F; Camphausen, KA; Halim, AS; Kambach, DM; Kramp, T; Patel, D; Stommel, JM; Sun, Q1
Chen, T; Chen, Z; Liu, L; Liu, Y; Nie, Y; Ouyang, Q; Wei, S; Yin, W; Zeng, F1
Benedetti, R; Cirone, M; D'Orazi, G; Garufi, A; Gilardini Montani, MS; Romeo, MA1
Abate, M; Bifulco, M; Ciaglia, E; Ciuffreda, P; D'Ursi, AM; Gazzerro, P; Grimaldi, M; Laezza, C; Manera, C; Pisanti, S; Ranieri, R; Rodriquez, M; Scrima, M1
Bao, S; Dong, Z; Fang, X; Gimple, RC; Huang, Z; Hubert, CG; Kim, LJY; Lai, S; Mack, SC; Mahadev, V; Miller, TE; Prager, BC; Rich, JN; Shi, Y; Song, A; Wang, X; Wu, Q; Xie, Q; Yang, K; Zhou, W; Zhu, Z1
Abbasi, T; Aggrawal, A; Bharati, IS; Chao, Y; Chien, S; Cong, X; Fogal, V; Jiang, P; Kapoor, S; Kesari, S; Mukthavaram, R; Nomura, N; Pastorino, S; Pingle, SC; Shetty, K; Teng, D; Vali, S1
Bifulco, M; Ciaglia, E; Comegna, M; D'Alessandro, A; Di Croce, L; Faraonio, R; Gazzerro, P; Laezza, C; Malfitano, AM; Picardi, P; Pisanti, S1
Hudgins, WR; Liu, L; Myers, CE; Oldfield, EH; Ram, Z; Samid, D; Shack, S; Walbridge, S1
Liu, L; Prasanna, P; Samid, D; Thibault, A1
Miller, AC; Samid, D1
Weiss, JF1
Fumagalli, R; Grossi-Paoletti, E; Paoletti, P1
Fiecchi, A; Galli, G; Grossi Paoletti, E; Paoletti, R; Scala, A1

Reviews

1 review(s) available for mevalonic acid and Brain Neoplasms

ArticleYear
Sterols and other lipids in tumors of the nervous system.
    Progress in biochemical pharmacology, 1975, Volume: 10

    Topics: Animals; Anticholesteremic Agents; Brain; Brain Neoplasms; Cholesterol; Desmosterol; Glycolipids; Humans; Lipid Metabolism; Lipids; Mevalonic Acid; Nerve Tissue; Peripheral Nerves; Peripheral Nervous System Neoplasms; Pharmacology; Phospholipids; Sterols; Time Factors; Triparanol

1975

Other Studies

12 other study(ies) available for mevalonic acid and Brain Neoplasms

ArticleYear
LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1.
    Scientific reports, 2019, 10-29, Volume: 9, Issue:1

    Topics: ATP Binding Cassette Transporter 1; Brain Neoplasms; Cell Proliferation; Cholesterol; Glioblastoma; Homeostasis; Humans; Lipid Metabolism; Liver X Receptors; Mevalonic Acid; Signal Transduction; Transcription, Genetic

2019
Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:1

    Topics: Artesunate; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Glioma; Humans; Hydroxymethylglutaryl CoA Reductases; Metabolic Networks and Pathways; Mevalonic Acid; Models, Biological; Protein Binding; Protein Transport; Sterol Regulatory Element Binding Protein 2; Transcription, Genetic; Tumor Suppressor Protein p53

2020
PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR.
    Biomolecules, 2020, 04-10, Volume: 10, Issue:4

    Topics: Brain Neoplasms; Butyric Acid; Cell Line, Tumor; Cell Survival; Down-Regulation; Glioblastoma; Humans; Mevalonic Acid; Mutant Proteins; Phenylbutyrates; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Protein Stability; Tumor Suppressor Protein p53; Unfolded Protein Response

2020
The isoprenoid derivative N
    British journal of pharmacology, 2017, Volume: 174, Issue:14

    Topics: Adenosine; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioma; Humans; Mevalonic Acid; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Terpenes

2017
MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells.
    Cancer research, 2017, 09-15, Volume: 77, Issue:18

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Glioblastoma; Humans; Isocitrate Dehydrogenase; Mevalonic Acid; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplastic Stem Cells; Proto-Oncogene Proteins c-myc; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2017
In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.
    British journal of cancer, 2014, Oct-14, Volume: 111, Issue:8

    Topics: Animals; Antineoplastic Agents; Autophagy; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Mevalonic Acid; Mice; Mice, Nude

2014
p53 regulates the mevalonate pathway in human glioblastoma multiforme.
    Cell death & disease, 2015, Oct-15, Volume: 6

    Topics: Brain Neoplasms; Cell Line, Tumor; Cholesterol; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Metabolic Networks and Pathways; Mevalonic Acid; Promoter Regions, Genetic; Transcription, Genetic; Tumor Suppressor Protein p53

2015
Selective activity of phenylacetate against malignant gliomas: resemblance to fetal brain damage in phenylketonuria.
    Cancer research, 1994, Feb-15, Volume: 54, Issue:4

    Topics: Animals; Brain; Brain Neoplasms; Female; Glioma; Humans; Mevalonic Acid; Mice; Mice, Nude; Phenylacetates; Phenylketonurias; Protein Prenylation; Rats; Rats, Inbred F344; Tumor Cells, Cultured

1994
Lipid metabolism as a target for brain cancer therapy: synergistic activity of lovastatin and sodium phenylacetate against human glioma cells.
    Journal of neurochemistry, 1996, Volume: 66, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Division; Drug Synergism; Glioma; Humans; Lipid Metabolism; Lovastatin; Mevalonic Acid; Neoplasm Invasiveness; Phenylacetates; Tumor Cells, Cultured; Ubiquinone

1996
Tumor radiosensitization based on the use of inhibitors of the mevalonate pathway of cholesterol synthesis.
    Advances in experimental medicine and biology, 1997, Volume: 400B

    Topics: Adenocarcinoma; Brain Neoplasms; Breast Neoplasms; Cell Survival; Cholesterol; Cobalt Radioisotopes; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexenes; Dose-Response Relationship, Radiation; Female; Fibrosarcoma; Gamma Rays; Genes, ras; Glioblastoma; Humans; Limonene; Lung Neoplasms; Male; Mevalonic Acid; Prostatic Neoplasms; Radiation-Sensitizing Agents; Terpenes; Tumor Cells, Cultured

1997
Lipids in brain tumors.
    Journal of neurosurgery, 1971, Volume: 34, Issue:3

    Topics: Animals; Brain Neoplasms; Cholesterol; Ependymoma; Glioblastoma; Glioma; Humans; In Vitro Techniques; Lipid Metabolism; Mevalonic Acid; Neoplasms, Experimental; Oligodendroglioma; Rats; Sterols

1971
Some pathways and mechanisms in lanosterol-cholesterol conversion in mammalian tissues.
    Lipids, 1971, Volume: 6, Issue:2

    Topics: Adult; Animals; Brain; Brain Neoplasms; Carbon Isotopes; Cholesterol; Glioblastoma; Humans; Liver; Male; Mevalonic Acid; Nerve Tissue; Rats; Sterols; Tritium

1971