Compounds > mevalonic acid

mevalonic acid and Astrocytoma, Grade IV

mevalonic acid has been researched along with Astrocytoma, Grade IV in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (16.67)	18.7374
1990's	1 (8.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	7 (58.33)	24.3611
2020's	2 (16.67)	2.80

Authors

Authors	Studies
Cui, X; Fang, C; Hong, B; Jiang, T; Kang, C; Li, G; Tan, Y; Tong, F; Wang, H; Wang, Q; Wang, Y; Xiao, M; Yang, C; Yang, S; Yi, K; Zhan, Q; Zhao, J; Zhou, J	1
Ahmad, F; Camphausen, KA; Halim, AS; Kambach, DM; Kramp, T; Patel, D; Stommel, JM; Sun, Q	1
Benedetti, R; Cirone, M; D'Orazi, G; Garufi, A; Gilardini Montani, MS; Romeo, MA	1
Bao, S; Dong, Z; Fang, X; Gimple, RC; Huang, Z; Hubert, CG; Kim, LJY; Lai, S; Mack, SC; Mahadev, V; Miller, TE; Prager, BC; Rich, JN; Shi, Y; Song, A; Wang, X; Wu, Q; Xie, Q; Yang, K; Zhou, W; Zhu, Z	1
Celsi, F; Crovella, S; Gratton, R; Tricarico, PM	1
Ghavami, S; Pirmoradi, L; Seyfizadeh, N; Shojaei, S; Zeki, AA	1
Bifulco, M; Ciaglia, E; Comegna, M; D'Alessandro, A; Di Croce, L; Faraonio, R; Gazzerro, P; Laezza, C; Malfitano, AM; Picardi, P; Pisanti, S	1
Chang, KC; Eun, SY; Hong, SC; Kang, ES; Kim, HJ; Kim, JH; Lee, JH; Seo, HG; Woo, IS	1
Imano, M; Itoh, T; Nishida, S; Satou, T; Tsubaki, M; Yamazoe, Y; Yanae, M	1
Miller, AC; Samid, D	1
Fumagalli, R; Grossi-Paoletti, E; Paoletti, P	1
Fiecchi, A; Galli, G; Grossi Paoletti, E; Paoletti, R; Scala, A	1

Reviews

1 review(s) available for mevalonic acid and Astrocytoma, Grade IV

Article	Year
Targeting cholesterol metabolism in glioblastoma: a new therapeutic approach in cancer therapy. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2019, Volume: 67, Issue:4 Topics: Animals; Autophagy; Cholesterol; Glioblastoma; Humans; Liver X Receptors; Mevalonic Acid; Molecular Targeted Therapy	2019

Other Studies

11 other study(ies) available for mevalonic acid and Astrocytoma, Grade IV

Article	Year
Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma. Cancer communications (London, England), 2023, Volume: 43, Issue:12 Topics: Animals; Cell Line, Tumor; Energy Metabolism; ErbB Receptors; Fatty Acids; Glioblastoma; Ligases; Mevalonic Acid; Proto-Oncogene Proteins c-akt; Temozolomide	2023
LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1. Scientific reports, 2019, 10-29, Volume: 9, Issue:1 Topics: ATP Binding Cassette Transporter 1; Brain Neoplasms; Cell Proliferation; Cholesterol; Glioblastoma; Homeostasis; Humans; Lipid Metabolism; Liver X Receptors; Mevalonic Acid; Signal Transduction; Transcription, Genetic	2019
PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR. Biomolecules, 2020, 04-10, Volume: 10, Issue:4 Topics: Brain Neoplasms; Butyric Acid; Cell Line, Tumor; Cell Survival; Down-Regulation; Glioblastoma; Humans; Mevalonic Acid; Mutant Proteins; Phenylbutyrates; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Protein Stability; Tumor Suppressor Protein p53; Unfolded Protein Response	2020
MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells. Cancer research, 2017, 09-15, Volume: 77, Issue:18 Topics: Animals; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Glioblastoma; Humans; Isocitrate Dehydrogenase; Mevalonic Acid; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplastic Stem Cells; Proto-Oncogene Proteins c-myc; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2017
Prolonged treatment with mevalonolactone induces oxidative stress response with reactive oxygen species production, mitochondrial depolarization and inflammation in human glioblastoma U-87 MG cells. Neurochemistry international, 2018, Volume: 120 Topics: Glioblastoma; Humans; Inflammation; Mevalonate Kinase Deficiency; Mevalonic Acid; Oxidative Stress; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Reactive Oxygen Species	2018
p53 regulates the mevalonate pathway in human glioblastoma multiforme. Cell death & disease, 2015, Oct-15, Volume: 6 Topics: Brain Neoplasms; Cell Line, Tumor; Cholesterol; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Metabolic Networks and Pathways; Mevalonic Acid; Promoter Regions, Genetic; Transcription, Genetic; Tumor Suppressor Protein p53	2015
Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. Neuroscience letters, 2010, Apr-26, Volume: 474, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Diphosphonates; Drug Synergism; Flow Cytometry; Geranyltranstransferase; Glioblastoma; Humans; JNK Mitogen-Activated Protein Kinases; Mevalonic Acid; Paclitaxel; Pamidronate; Polyisoprenyl Phosphates; Sesquiterpenes; Signal Transduction; Time Factors; Tumor Suppressor Protein p53	2010
Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma. Journal of experimental & clinical cancer research : CR, 2011, Aug-10, Volume: 30 Topics: Acyl Coenzyme A; Apoptosis; Cell Growth Processes; Cell Survival; Enzyme Activation; Female; Glioblastoma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mevalonic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-akt	2011
Tumor radiosensitization based on the use of inhibitors of the mevalonate pathway of cholesterol synthesis. Advances in experimental medicine and biology, 1997, Volume: 400B Topics: Adenocarcinoma; Brain Neoplasms; Breast Neoplasms; Cell Survival; Cholesterol; Cobalt Radioisotopes; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexenes; Dose-Response Relationship, Radiation; Female; Fibrosarcoma; Gamma Rays; Genes, ras; Glioblastoma; Humans; Limonene; Lung Neoplasms; Male; Mevalonic Acid; Prostatic Neoplasms; Radiation-Sensitizing Agents; Terpenes; Tumor Cells, Cultured	1997
Lipids in brain tumors. Journal of neurosurgery, 1971, Volume: 34, Issue:3 Topics: Animals; Brain Neoplasms; Cholesterol; Ependymoma; Glioblastoma; Glioma; Humans; In Vitro Techniques; Lipid Metabolism; Mevalonic Acid; Neoplasms, Experimental; Oligodendroglioma; Rats; Sterols	1971
Some pathways and mechanisms in lanosterol-cholesterol conversion in mammalian tissues. Lipids, 1971, Volume: 6, Issue:2 Topics: Adult; Animals; Brain; Brain Neoplasms; Carbon Isotopes; Cholesterol; Glioblastoma; Humans; Liver; Male; Mevalonic Acid; Nerve Tissue; Rats; Sterols; Tritium	1971