mevalonic acid and Arteriosclerosis

mevalonic acid has been researched along with Arteriosclerosis in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199012 (37.50)18.7374
1990's8 (25.00)18.2507
2000's12 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Laufs, U1
Chao, JT; Gapor, A; Theriault, A1
Anel, RL; Danesh, FR; Kanwar, YS; Lomasney, J; Sahai, A; Zeng, L1
Burger, F; Graber, P; Kwak, BR; Lüscher, TF; Mach, F; Matter, CM; Mulhaupt, F; Pelli, G; Veillard, NR1
Benderitter, M; Gaugler, MH; Squiban, C; Vandamme, M; Vereycken-Holler, V; Vozenin-Brotons, MC1
März, W; Scharnagl, H1
Kritchevsky, D; Tepper, SA1
Bernini, F; Corsini, A; Fumagalli, R; Paoletti, R; Raiteri, M; Soma, MR1
Catapano, AL; Corsini, A; Maggi, FM1
Himberg, JJ; Jokelainen, K; Karila, T; Laaksonen, R; Seppälä, T1
Camera, M; Colli, S; Eligini, S; Lalli, M; Paoletti, R; Tremoli, E1
Biwa, T; Hakamata, H; Horiuchi, S; Kobori, S; Matsumura, T; Sakai, M; Sato, Y; Shichiri, M; Takemura, T1
De Caterina, R; Lenzi, S1
La Fata, V; Laufs, U; Liao, JK; Plutzky, J1
Komukai, M; Morisaki, N; Saito, Y; Shinomiya, M; Tashiro, J; Wajima, YS1
Breithardt, G; Schmidt, A; Sindermann, JR1
Palinski, W1
Chen, H; Ikeda, M; Ikeda, U; Minota, S; Shimada, K; Shimpo, M1
Joseph, SB; Kast, HR; Laffitte, BA; Mangelsdorf, DJ; Repa, JJ; Tontonoz, P; Wilpitz, DC1
Badimon, L; Martínez-González, J; Raposo, B; Rodríguez, C1
Berthold, HK; Brämswig, S; Kerksiek, A; Luers, C; Sudhop, T; Von Bergmann, K1
Kalra, VK1
Blankenhorn, DH; Kalra, VK1
Klimov, AN1
Kim, HK; Kritchevsky, D; Moses, DE; Story, JA; Tepper, SA1
Collins, PB; Devery, RA; Johnson, AH; O'Meara, N; Scott, L; Tomkin, GH1
Barbu, V; Fairbanks, KP; Goodman, DS; Witte, LD1
Lynen, F1
Jungmann, RA; Schweppe, JS1
Bullock, BC; Clarkson, TB; Lehner, ND; Lofland, HB; St Clair, RW1
Brus, R; Chruściel, T; Herman, Z1
Clarkson, TB; Lofland, HB; Prichard, RW; St Clair, RW1

Reviews

6 review(s) available for mevalonic acid and Arteriosclerosis

ArticleYear
Beyond lipid-lowering: effects of statins on endothelial nitric oxide.
    European journal of clinical pharmacology, 2003, Volume: 58, Issue:11

    Topics: Arteriosclerosis; Cholesterol; Clinical Trials as Topic; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Mevalonic Acid; Nitric Oxide; Oxidative Stress

2003
Immunomodulatory effects of HMG-CoA reductase inhibitors.
    Archivum immunologiae et therapiae experimentalis, 2003, Volume: 51, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Arteriosclerosis; Cell Line; Cholesterol; Clinical Trials as Topic; Guanosine Triphosphate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interferon-gamma; Mevalonic Acid; Models, Biological; T-Lymphocytes; Transplantation

2003
New lipid-lowering agents acting on LDL receptors.
    Current topics in medicinal chemistry, 2005, Volume: 5, Issue:3

    Topics: Arteriosclerosis; Cholesterol, LDL; Farnesyl-Diphosphate Farnesyltransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lipid Metabolism; Lipids; Mevalonic Acid; Receptors, LDL; Transcription, Genetic

2005
Pharmacology of competitive inhibitors of HMG-CoA reductase.
    Pharmacological research, 1995, Volume: 31, Issue:1

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cattle; Cells, Cultured; Chick Embryo; Cholesterol; Cricetinae; Dogs; Guinea Pigs; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipids; Lipoproteins; Lovastatin; Mevalonic Acid; Mice; Organ Specificity; Rabbits; Rats; Simvastatin

1995
[Prevention and therapy of vascular damage and endothelial dysfunction with hypocholesteremic agents].
    Giornale italiano di cardiologia, 1998, Volume: 28, Issue:2

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diet; Endothelium, Vascular; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Mevalonic Acid; Middle Aged; Physical Exertion; Primary Prevention; Simvastatin; Time Factors

1998
Hormones and cholesterol ester metabolism.
    Journal of the American Geriatrics Society, 1969, Volume: 17, Issue:8

    Topics: Acetates; Adrenocorticotropic Hormone; Animals; Arachidonic Acids; Arteriosclerosis; Bile Acids and Salts; Biological Transport; Cholesterol; Diet; Epinephrine; Esters; Estradiol; Female; Hydrolases; Insulin; Intestinal Absorption; Ligases; Linoleic Acids; Lipoproteins; Liver; Mevalonic Acid; Microsomes; Oleic Acids; Palmitic Acids; Rats; Testosterone; Thyroxine; Transferases

1969

Trials

1 trial(s) available for mevalonic acid and Arteriosclerosis

ArticleYear
Carbamazepine increases atherogenic lipoproteins: mechanism of action in male adults.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Adult; Anticonvulsants; Arteriosclerosis; Body Composition; Body Weight; Carbamazepine; Cholestanol; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Diet; Humans; Hydrocortisone; Intestinal Absorption; Lipoproteins; Male; Mevalonic Acid; Phytosterols; Sitosterols

2002

Other Studies

25 other study(ies) available for mevalonic acid and Arteriosclerosis

ArticleYear
Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion.
    Journal of nutritional science and vitaminology, 2002, Volume: 48, Issue:5

    Topics: Arteriosclerosis; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Models, Biological; Monocytes; Tocotrienols; Umbilical Veins; Vitamin E

2002
Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells.
    Cardiovascular research, 2003, Sep-01, Volume: 59, Issue:3

    Topics: Animals; Arteriosclerosis; Atorvastatin; Blotting, Western; CD40 Antigens; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Endothelial Cells; Fibroblasts; Flow Cytometry; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Interferon-gamma; Lovastatin; Macrophages; Mevalonic Acid; Mice; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Pravastatin; Pyrroles; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Simvastatin; Transcription Factors

2003
Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses.
    Radiation research, 2005, Volume: 163, Issue:5

    Topics: Arteriosclerosis; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Mevalonic Acid; NF-kappa B; Pravastatin; Radiotherapy; Thrombosis

2005
Influence of pyridinolcarbamate on hepatic cholesterogenesis in rats.
    Experientia, 1967, Dec-15, Volume: 23, Issue:12

    Topics: Acetates; Animals; Anticholesteremic Agents; Arteriosclerosis; Carbamates; Carbon Isotopes; Cholesterol; Liver; Male; Mevalonic Acid; Organ Size; Pyridines; Rats

1967
Pathogenesis of atherosclerosis and the role of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.
    The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cell Division; Cell Movement; Cells, Cultured; Cholesterol Esters; Diterpenes; Farnesol; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Macrophages, Peritoneal; Male; Mevalonic Acid; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Pravastatin; Rabbits; Rats; Rats, Sprague-Dawley; Simvastatin

1995
The effects of anabolic androgenic steroids on serum ubiquinone and dolichol levels among steroid abusers.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:7

    Topics: Adult; Anabolic Agents; Arteriosclerosis; Cholesterol, HDL; Cholesterol, LDL; Dolichols; Humans; Male; Mevalonic Acid; Substance-Related Disorders; Ubiquinone

1996
Vastatins inhibit tissue factor in cultured human macrophages. A novel mechanism of protection against atherothrombosis.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:2

    Topics: Arteriosclerosis; Blood Cells; Cells, Cultured; Cholesterol; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipopolysaccharides; Macrophages; Mevalonic Acid; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; RNA, Messenger; Thromboplastin; Thrombosis

1997
HMG-CoA reductase inhibitors suppress macrophage growth induced by oxidized low density lipoprotein.
    Atherosclerosis, 1997, Volume: 133, Issue:1

    Topics: Animals; Arteriosclerosis; Cell Division; Cholesterol; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Macrophages; Male; Mevalonic Acid; Mice; Mice, Inbred C3H; Oxidation-Reduction; Pravastatin; Simvastatin

1997
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors.
    Circulation, 1998, Mar-31, Volume: 97, Issue:12

    Topics: Animals; Aorta; Arteriosclerosis; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Nitric Oxide Synthase; RNA, Messenger; Saphenous Vein; Simvastatin; Transcription, Genetic

1998
Carvastatin suppresses intimal thickening of rabbit carotid artery after balloon catheter injury probably through the inhibition of vascular smooth muscle cell proliferation and migration.
    Scandinavian journal of clinical and laboratory investigation, 1999, Volume: 59, Issue:3

    Topics: Animals; Anticoagulants; Arteriosclerosis; Becaplermin; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; Cell Division; Cell Movement; Cholesterol, LDL; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Naphthalenes; Platelet-Derived Growth Factor; Pravastatin; Proto-Oncogene Proteins c-sis; Pyrans; Rabbits; Receptors, LDL; Tumor Cells, Cultured; Tunica Intima

1999
Upregulation of the interleukin-8 system in hypercholesterolemic patients. Does inhibition of the mevalonate pathway lower interleukin-8 levels in the vessel wall?
    Atherosclerosis, 2000, Volume: 150, Issue:2

    Topics: Antibodies, Monoclonal; Arteriosclerosis; Biomarkers; Blood Vessels; Cell Division; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Interleukin-8; Mevalonic Acid; Muscle, Smooth, Vascular; Up-Regulation

2000
Immunomodulation: a new role for statins?
    Nature medicine, 2000, Volume: 6, Issue:12

    Topics: Adjuvants, Immunologic; Anticholesteremic Agents; Arteries; Arteriosclerosis; Cholesterol; Gene Expression Regulation; Genes, MHC Class II; Histocompatibility Antigens Class II; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Models, Immunological; T-Lymphocytes

2000
Fluvastatin upregulates inducible nitric oxide synthase expression in cytokine-stimulated vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:6

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cells, Cultured; Cytokines; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Gene Expression; Indoles; Mevalonic Acid; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; RNA, Messenger; Up-Regulation

2000
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2

    Topics: 3T3 Cells; Adipocytes; Animals; Anticholesteremic Agents; Apolipoproteins E; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Hepatocellular; Cell Differentiation; Cells, Cultured; Cholesterol; Diet, Atherogenic; Dimerization; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Hydrocarbons, Fluorinated; Hydroxycholesterols; Ligands; Lipids; Liver Neoplasms; Liver X Receptors; Lovastatin; Macrophages, Peritoneal; Male; Mevalonic Acid; Mice; Mice, Knockout; Organic Chemicals; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured

2001
3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:5

    Topics: Arteriosclerosis; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Mevalonic Acid; Nitric Oxide Synthase; Promoter Regions, Genetic; RNA Stability; RNA, Messenger; Simvastatin; Transcription, Genetic

2001
Studies on the regulation of sterol synthesis in lymphocytes from atherosclerotic-susceptible and -resistant pigeons. Efflux of sterols and membrane fluidity.
    Archives of biochemistry and biophysics, 1977, Volume: 184, Issue:1

    Topics: Acetates; Animals; Arteriosclerosis; Cell Membrane; Columbidae; Culture Media; Kinetics; Lymphocytes; Membrane Lipids; Mevalonic Acid; Phospholipids; Species Specificity; Spectrometry, Fluorescence; Sterols; Temperature

1977
Abnormal activation of sterol synthesis in lymphocytes of atherosclerotic-susceptible pigeons and heterozygous familial hypercholesterolemic patients.
    Biochimica et biophysica acta, 1976, Aug-23, Volume: 441, Issue:2

    Topics: Acetates; Adult; Animals; Arteriosclerosis; Cholesterol; Columbidae; Cycloheximide; Humans; Hypercholesterolemia; Lipid Metabolism; Lymphocytes; Mevalonic Acid; Sterols

1976
[Role of physiologically active substances in the pathogenesis and therapy of atherosclerosis].
    Vestnik Akademii meditsinskikh nauk SSSR, 1976, Issue:9

    Topics: Animals; Arteriosclerosis; Carbamates; Chondroitin; Chondroitin Sulfates; Mevalonic Acid; Pyridinolcarbamate; Rabbits

1976
Experimental atherosclerosis in rabbits fed cholesterol-free diets. 4. Investigation into the source of cholesteremia.
    Experimental and molecular pathology, 1975, Volume: 22, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Autopsy; Bile Acids and Salts; Carbon Radioisotopes; Cholesterol; Cholesterol, Dietary; Chromatography, Thin Layer; Diet, Atherogenic; Dietary Carbohydrates; Disease Models, Animal; Injections, Intraperitoneal; Lipids; Liver; Male; Mevalonic Acid; Rabbits; Triglycerides; Tritium

1975
A comparative study of the rate-limiting enzymes of cholesterol synthesis, esterification and catabolism in the rat and rabbit.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1987, Volume: 87, Issue:4

    Topics: Animals; Arteriosclerosis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Hydroxymethylglutaryl CoA Reductases; Intestinal Mucosa; Kinetics; Male; Mevalonic Acid; Microsomes, Liver; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Steroid Hydroxylases; Sterol O-Acyltransferase

1987
Studies on cell proliferation and mevalonic acid metabolism in cultured human fibroblasts.
    Annals of the New York Academy of Sciences, 1985, Volume: 454

    Topics: Arteriosclerosis; Cell Division; Cells, Cultured; Culture Media; Fibroblasts; Humans; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Mevalonic Acid; Naphthalenes; Platelet-Derived Growth Factor

1985
[The biochemical basis of the biosynthesis of cholesterol and fatty acids].
    Wiener klinische Wochenschrift, 1966, Jul-08, Volume: 78, Issue:27

    Topics: Alkenes; Animals; Arteriosclerosis; Brain; Cholesterol; Diphosphates; Fatty Acids; Humans; Ligases; Liver Extracts; Mevalonic Acid; Saccharomyces; Squalene; Terpenes; Tissue Extracts

1966
Atherosclerosis in Cebus monkeys. II. Arterial metabolism.
    Experimental and molecular pathology, 1968, Volume: 9, Issue:1

    Topics: Acetates; Animals; Aorta; Arteries; Arteriosclerosis; Carbon Isotopes; Cholesterol; Diet, Atherogenic; Esters; Female; Haplorhini; Lipid Metabolism; Lipids; Male; Mevalonic Acid; Perfusion; Phospholipids; Squalene; Triglycerides

1968
Atherosclerotic lesions induced by loustalot's diet in rats treated with Benzmalecene.
    Acta physiologica Polonica, 1967, Volume: 18, Issue:3

    Topics: Animals; Aorta; Arteriosclerosis; Benzene Derivatives; Cholesterol; Female; In Vitro Techniques; Liver; Male; Maleates; Mevalonic Acid; Rats

1967
Synthesis of squalene and sterols by isolated segments of human and pigeon arteries.
    Experimental and molecular pathology, 1968, Volume: 8, Issue:2

    Topics: Animals; Arteries; Arteriosclerosis; Carbon Isotopes; Cholesterol; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Thin Layer; Columbidae; Humans; Mevalonic Acid; Perfusion; Renal Artery; Squalene; Sterols

1968