metyrapone has been researched along with Spasms, Infantile in 2 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The metyrapone test was used to study the hypothalamo-pituitary-adrenal function in ten children with infantile spasms, before and after ACTH treatment." | 1.27 | Hypothalamo-pituitary-adrenal function in infantile spasms: effects of ACTH therapy. ( Rao, JK; Willis, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rao, JK | 1 |
| Willis, J | 1 |
| Okada, S | 1 |
2 other studies available for metyrapone and Spasms, Infantile
| Article | Year |
|---|---|
Hypothalamo-pituitary-adrenal function in infantile spasms: effects of ACTH therapy.
Topics: Adrenocorticotropic Hormone; Cortodoxone; Female; Humans; Hydrocortisone; Infant; Male; Metyrapone; | 1987 |
[Study of focal epilepsy].
Topics: Adrenocorticotropic Hormone; Animals; Brain; Child, Preschool; Electroencephalography; Female; Human | 1967 |