metyrapone has been researched along with Shock in 2 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Shock: A pathological condition manifested by failure to perfuse or oxygenate vital organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the process of developing a model of Escherichia coli endotoxin-induced acute lung injury and shock in specific pathogen-free pigs, the effects of pretreatment with metyrapone (a cortisol-synthesis inhibitor) were examined." | 3.70 | Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock, and nitric oxide production. ( Alving, K; Bergman, D; Middelveld, RJ; Wanecek, M; Weitzberg, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Middelveld, RJ | 1 |
| Wanecek, M | 1 |
| Bergman, D | 1 |
| Weitzberg, E | 1 |
| Alving, K | 1 |
| Egan, TJ | 1 |
| Kenny, FM | 1 |
| Jarrah, A | 1 |
| Holliday, MA | 1 |
2 other studies available for metyrapone and Shock
| Article | Year |
|---|---|
Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock, and nitric oxide production.
Topics: Acid-Base Imbalance; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Disease Models, Anim | 1999 |
Shock as a complication of the nephrotic syndrome.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Blood Proteins; Child; Child, Pr | 1967 |