metyrapone has been researched along with Schizophrenia in 8 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The metyrapone test was applied to groups of patients suffering from major depressive illness with melancholia, mania or schizophrenia, before and after treatment." | 7.67 | The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984) |
| "The metyrapone test was applied to patients suffering from major depressive illness with melancholia, from mania, and from schizophrenia." | 7.67 | The metyrapone test in affective disorders and schizophrenia. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984) |
| "The metyrapone test was applied to groups of patients suffering from major depressive illness with melancholia, mania or schizophrenia, before and after treatment." | 3.67 | The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984) |
| "The metyrapone test was applied to patients suffering from major depressive illness with melancholia, from mania, and from schizophrenia." | 3.67 | The metyrapone test in affective disorders and schizophrenia. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SAARIMAA, HA | 1 |
| SOURANDER, C | 1 |
| RINNE, UK | 1 |
| SCHOU, M | 1 |
| Moroji, T | 1 |
| Endo, M | 1 |
| Yamazaki, K | 1 |
| Kato, H | 1 |
| Perini, GI | 3 |
| Fava, GA | 3 |
| Morphy, MA | 3 |
| Carson, SW | 3 |
| Molnar, G | 3 |
| Jusko, WJ | 3 |
| Goldman, MB | 1 |
| Wood, GJ | 1 |
| Brambilla, F | 1 |
| Cazzulo, CL | 1 |
| Penati, G | 1 |
1 trial available for metyrapone and Schizophrenia
| Article | Year |
|---|---|
Adrenocorticotropin inhibition by restoration of normal evening cortisol levels: a measure of putative hippocampus-mediated glucocorticoid feedback in humans.
Topics: Adrenocorticotropic Hormone; Adult; Double-Blind Method; Feedback; Female; Glucocorticoids; Hippocam | 2000 |
7 other studies available for metyrapone and Schizophrenia
| Article | Year |
|---|---|
THE EFFECT OF CHLORPROMAZIN ON THE SECRETION OF CORTICOTROPHIN IN PSYCHIATRIC PATIENTS EXAMINED BY THE METOPIRON TEST.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Chlorpromazine; Geriatrics; Humans; Ketones; M | 1963 |
CLINICAL AND BIOCHEMICAL EFFECTS OF PSYCHOPHARMACA.
Topics: Adrenocorticotropic Hormone; Chlorpromazine; Metyrapone; Mineralocorticoid Receptor Antagonists; Pit | 1963 |
[Effect of chlorpromazine upon the hypothalamopituitary-adrenocortical functions].
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adult; Chlorpromazine; Convulsive Therapy; Female; Humans | 1966 |
The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment.
Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Cortodoxone; Depressive | 1984 |
The metyrapone test in affective disorders and schizophrenia.
Topics: Adult; Aged; Bipolar Disorder; Cortodoxone; Depressive Disorder; Dexamethasone; Female; Humans; Hydr | 1984 |
The metyrapone test in schizophrenic patients and healthy subjects.
Topics: Adult; Cortodoxone; Dexamethasone; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; M | 1985 |
[Hormones and schizophrenia].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Endocrine Glands; Estrogens | 1974 |