metyrapone has been researched along with Reperfusion Injury in 6 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models." | 5.31 | Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001) |
| "Metyrapone pretreatment shortly inhibited corticosterone rise, caused by ischemic preconditioning, and prevented the gastroprotective action of ischemic preconditioning." | 1.35 | Ischemic preconditioning attenuates gastric ischemia-reperfusion injury through involvement of glucocorticoids. ( Bagaeva, T; Bobryshev, P; Filaretova, L, 2009) |
| "In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models." | 1.31 | Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Filaretova, LP | 3 |
| Bagaeva, TR | 2 |
| Morozova, OIu | 1 |
| Bobryshev, P | 1 |
| Bagaeva, T | 1 |
| Filaretova, L | 1 |
| Milot, MR | 1 |
| Plamondon, H | 1 |
| Bobryshev, PIu | 2 |
| Bagaeva, TP | 1 |
| Komkova, OP | 1 |
| Schurr, A | 1 |
| Payne, RS | 1 |
| Miller, JJ | 1 |
| Tseng, MT | 1 |
6 other studies available for metyrapone and Reperfusion Injury
| Article | Year |
|---|---|
[Gastroprotective action of corticotropin-releasing factor (CRF): involvement of glucocorticoids and CRF receptors type 2].
Topics: Animals; Antimetabolites; Cold Temperature; Corticosterone; Corticotropin-Releasing Hormone; Gastric | 2012 |
Ischemic preconditioning attenuates gastric ischemia-reperfusion injury through involvement of glucocorticoids.
Topics: Adrenalectomy; Animals; Celiac Artery; Corticosterone; Enzyme Inhibitors; Gastric Mucosa; Hormone An | 2009 |
How right is the righting reflex? The risk of false positives in neuroprotection studies using behavioral measures to certify forebrain ischemia.
Topics: Animals; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Memory Disor | 2010 |
[Contribution of glucocorticoid hormones to gastroprotective effect of ischemic preconditioning in rats with normal and deficient prostaglandin production].
Topics: Adrenalectomy; Animals; Corticosterone; Gastric Mucosa; Glucocorticoids; Indomethacin; Ischemic Prec | 2010 |
[Role of glucocorticoids and capsaicin-sensitive neurons in gastroprotective effect of ischemic preconditioning].
Topics: Adrenalectomy; Animals; Capsaicin; Corticosterone; Ischemic Preconditioning; Male; Metyrapone; Neuro | 2012 |
Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Glucose; Brain Ischemia; Corticostero | 2001 |