metyrapone has been researched along with Recrudescence in 14 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To control hypercortisolism, the patient was treated with metyrapone." | 6.41 | Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone. ( Dokoupilová, M; Hána, V; Marek, J; Plavka, R, 2001) |
| "To control hypercortisolism, the patient was treated with metyrapone." | 2.41 | Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone. ( Dokoupilová, M; Hána, V; Marek, J; Plavka, R, 2001) |
| "We report three cases of long-term treatment of ectopic ACTH syndrome due to metastatic bronchial carcinoid, islet cell carcinoma, and malignant thymoma tumors." | 2.40 | Long-term medical treatment of ectopic ACTH syndrome. ( Comi, RJ; Gorden, P, 1998) |
| "The metyrapone test is a useful test in the assessment of outcome of pituitary surgery for Cushing's disease, with a sensitivity of 100% and a specificity of 75% for the early detection of patients at risk of a relapse." | 1.30 | Postoperative metyrapone test in the early assessment of outcome of pituitary surgery for Cushing's disease. ( de Herder, WW; de Jong, FH; Lamberts, SW; van Aken, MO; van der Lely, AJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galesi, FL | 1 |
| Ayanwuyi, LO | 1 |
| Mijares, MG | 1 |
| Cippitelli, A | 1 |
| Cannella, N | 1 |
| Ciccocioppo, R | 1 |
| Ubaldi, M | 1 |
| Broadley, AJ | 1 |
| Korszun, A | 1 |
| Abdelaal, E | 1 |
| Moskvina, V | 1 |
| Deanfield, J | 1 |
| Jones, CJ | 1 |
| Frenneaux, MP | 1 |
| van Aken, MO | 1 |
| de Herder, WW | 1 |
| van der Lely, AJ | 1 |
| de Jong, FH | 1 |
| Lamberts, SW | 1 |
| Hermus, AR | 1 |
| Comi, RJ | 1 |
| Gorden, P | 1 |
| Hána, V | 1 |
| Dokoupilová, M | 1 |
| Marek, J | 1 |
| Plavka, R | 1 |
| Miró, J | 1 |
| Amado, JA | 1 |
| Pesquera, C | 1 |
| López-Cordovilla, JJ | 1 |
| Berciano, J | 1 |
| Littley, MD | 1 |
| Shalet, SM | 1 |
| Beardwell, CG | 1 |
| Ahmed, SR | 1 |
| Sutton, ML | 1 |
| Carpenter, PC | 1 |
| Pratt, JH | 1 |
| Sawin, CT | 1 |
| Melby, JC | 1 |
| Tuft, L | 1 |
| Siegal, AM | 1 |
| Kreisberg, RA | 1 |
| Hershman, JM | 1 |
| Owen, WC | 1 |
| Maki, S | 1 |
| Iida, H | 1 |
| Yoshida, N | 1 |
| Schteingart, DE | 1 |
| Conn, JW | 1 |
| Lieberman, LM | 1 |
| Beierwaltes, WH | 1 |
3 reviews available for metyrapone and Recrudescence
| Article | Year |
|---|---|
Long-term medical treatment of ectopic ACTH syndrome.
Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenocortical Hyperfunction; Aminoglutethimide; Antineoplastic | 1998 |
Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone.
Topics: Abortion, Therapeutic; Adolescent; Adrenal Glands; Cesarean Section; Cushing Syndrome; Female; Fetal | 2001 |
Cushing's syndrome: update of diagnosis and management.
Topics: Adenoma; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushin | 1986 |
2 trials available for metyrapone and Recrudescence
| Article | Year |
|---|---|
Metyrapone improves endothelial dysfunction in patients with treated depression.
Topics: Adult; Antidepressive Agents; Brachial Artery; Coronary Disease; Depressive Disorder; Double-Blind M | 2006 |
Long-term follow-up of low-dose external pituitary irradiation for Cushing's disease.
Topics: Adolescent; Adrenalectomy; Adult; Aged; Child; Cushing Syndrome; Female; Follow-Up Studies; Humans; | 1990 |
9 other studies available for metyrapone and Recrudescence
| Article | Year |
|---|---|
Role of Hypothalamic-Pituitary-Adrenal axis and corticotropin-releasing factor stress system on cue-induced relapse to alcohol seeking.
Topics: Animals; Behavior, Addictive; Corticotropin-Releasing Hormone; Cues; Ethanol; Hypothalamo-Hypophysea | 2016 |
Postoperative metyrapone test in the early assessment of outcome of pituitary surgery for Cushing's disease.
Topics: Adolescent; Adult; Cortodoxone; Cushing Syndrome; Dexamethasone; Female; Glucocorticoids; Humans; Hy | 1997 |
Early assessment of outcome of pituitary surgery for Cushing's disease.
Topics: Cushing Syndrome; Humans; Hydrocortisone; Metyrapone; Pituitary Gland; Postoperative Period; Recurre | 1997 |
Assessment of the hypothalamic-pituitary-adrenal axis function after corticosteroid therapy for MS relapses.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Cortodoxone; Female; Humans; Hydrocortisone; Hypotha | 1990 |
Remission of Cushing's disease after administration of adrenocorticotropin.
Topics: 17-Hydroxycorticosteroids; Administration, Oral; Adrenal Glands; Adrenal Insufficiency; Adrenocortic | 1974 |
Corticosteroids in the unresponsive asthmatic patient.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aminophylline; Asthma; Child; Child, Preschool | 1971 |
Recurrent Cushing's disease following "total" adrenalectomy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormo | 1972 |
Studies on the adrenocortical hormone therapy in idiopathic nephrotic syndrome in children.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Child; | 1972 |
Persistent or recurrent Cushing's syndrome after "total" adrenalectomy: adrenal photoscanning for residual tissue.
Topics: 17-Hydroxycorticosteroids; Adrenalectomy; Adult; Cholesterol; Cushing Syndrome; Dexamethasone; Femal | 1972 |