metyrapone has been researched along with Pyrexia in 10 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "7 microgram/kg] induce monophasic fever, increase anterior and posterior pituitary hormone release, and enhance hypothalamic c-Fos expression in pigs, all of which can be prevented by indomethacin (Ind)." | 3.69 | Interrelated adrenocortical and neurohypophysial responses associated with fever in endotoxin-treated pigs. ( Forsling, ML; Goode, JA; Lloyd, DM; Parrott, RF; Vellucci, SV, 1997) |
| "Striking parallels exist between the neurochemical and toxic effects of stress and methamphetamine." | 1.35 | Chronic stress enhances methamphetamine-induced extracellular glutamate and excitotoxicity in the rat striatum. ( Tata, DA; Yamamoto, BK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, BN | 1 |
| Yamamoto, BK | 2 |
| Drouet, JB | 1 |
| Michel, V | 1 |
| Peinnequin, A | 1 |
| Alonso, A | 1 |
| Fidier, N | 1 |
| Maury, R | 1 |
| Buguet, A | 1 |
| Cespuglio, R | 1 |
| Canini, F | 1 |
| Alexander, BN | 1 |
| Fewell, JE | 1 |
| Tata, DA | 1 |
| Parrott, RF | 1 |
| Vellucci, SV | 1 |
| Goode, JA | 1 |
| Lloyd, DM | 1 |
| Forsling, ML | 1 |
| Bacchus, H | 1 |
| Fehér, T | 1 |
| Halmy, L | 1 |
| Hellman, L | 1 |
| Bradlow, HL | 1 |
| Zumoff, B | 1 |
| Jacobs, HS | 1 |
| Nabarro, JD | 1 |
| Wegelius, O | 1 |
| Keyriläinen, O | 1 |
| Vihko, R | 1 |
| Adlercreutz, H | 1 |
1 review available for metyrapone and Pyrexia
| Article | Year |
|---|---|
Recent advances in human steroid metabolism.
Topics: Adrenocorticotropic Hormone; Aldosterone; Carbon Isotopes; Dexamethasone; Estriol; Etiocholanolone; | 1970 |
9 other studies available for metyrapone and Pyrexia
| Article | Year |
|---|---|
Chronic unpredictable stress augments +3,4-methylenedioxymethamphetamine-induced monoamine depletions: the role of corticosterone.
Topics: Animals; Body Temperature; Brain; Corpus Striatum; Corticosterone; Dopamine; Enzyme Inhibitors; Feve | 2009 |
Metyrapone blunts stress-induced hyperthermia and increased locomotor activity independently of glucocorticoids and neurosteroids.
Topics: Algorithms; Animals; Antimetabolites; Down-Regulation; Drug Evaluation, Preclinical; Fever; Glucocor | 2010 |
Metyrapone restores the febrile response to Escherichia coli LPS in pregnant rats.
Topics: Animals; Body Temperature; Body Temperature Regulation; Corticosterone; Enzyme Inhibitors; Escherich | 2011 |
Chronic stress enhances methamphetamine-induced extracellular glutamate and excitotoxicity in the rat striatum.
Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Chronic Disease; Dopamine; Dopamin | 2008 |
Interrelated adrenocortical and neurohypophysial responses associated with fever in endotoxin-treated pigs.
Topics: Analgesics, Non-Narcotic; Animals; Body Temperature Regulation; Dexamethasone; Endotoxins; Escherich | 1997 |
Sequential solvent extraction of urinary corticosteroids and its clinical application.
Topics: 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticotrop | 1967 |
The conjugating mechanism in a case of etiocholanolone fever.
Topics: Adolescent; Adrenocorticotropic Hormone; Androsterone; Dehydroepiandrosterone; Etiocholanolone; Fema | 1968 |
Tests of hypothalamic-pituitary-adrenal function in man.
Topics: Acromegaly; Adrenal Glands; Adult; Aged; Cushing Syndrome; Female; Fever; Glucocorticoids; Growth Ho | 1969 |
Successful treatment of periodic ("etiocholanolone") fever with metyrapone combined with a low dose of dexamethasone.
Topics: Adult; Aged; Dexamethasone; Etiocholanolone; Fever; Humans; Male; Metyrapone; Middle Aged; Periodici | 1970 |