Page last updated: 2024-10-31

metyrapone and Psychotic Disorders

metyrapone has been researched along with Psychotic Disorders in 7 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"The metyrapone test was applied to groups of patients suffering from major depressive illness with melancholia, mania or schizophrenia, before and after treatment."7.67The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984)
"The metyrapone test was applied to groups of patients suffering from major depressive illness with melancholia, mania or schizophrenia, before and after treatment."3.67The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okumura, T1
Takayama, S1
Nishio, SI1
Miyakoshi, T1
Noguchi, T1
Kobayashi, T1
Fukushima, T1
Sekiguchi, N1
Otsuki, T1
Komatsu, M1
Koizumi, T1
Hui, X1
Zhou, CH1
Wang, MW1
Myhill, PC1
Sillars, BA1
Starkstein, S1
Annus, T1
Yeap, BB1
Perini, GI2
Fava, GA2
Morphy, MA2
Carson, SW2
Molnar, G2
Jusko, WJ2
Ghadirian, AM1
Engelsmann, F1
Dhar, V1
Filipini, D1
Keller, R1
Chouinard, G1
Murphy, BE1
Newmark, SR1
Dluhy, RG1
Bennett, AH1

Reviews

2 reviews available for metyrapone and Psychotic Disorders

ArticleYear
ACTH-producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review.
    Thoracic cancer, 2019, Volume: 10, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Female; Humans; Metyrapone; Multiple Pulmonary Nodules; Neuroend

2019
Glucocorticoid receptor and treatment of psychotic major depression.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11

    Topics: Animals; Brain; Dehydroepiandrosterone; Depressive Disorder, Major; Humans; Metyrapone; Mifepristone

2005

Other Studies

5 other studies available for metyrapone and Psychotic Disorders

ArticleYear
Reduction in salivary cortisol concentration correlates with resolution of psychosis in Cushing's syndrome.
    The Journal of neuropsychiatry and clinical neurosciences, 2008,Winter, Volume: 20, Issue:1

    Topics: Antimetabolites; Cushing Syndrome; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Psychotic

2008
The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment.
    Journal of affective disorders, 1984, Volume: 7, Issue:3-4

    Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Cortodoxone; Depressive

1984
The metyrapone test in manic patients and healthy subjects.
    Pharmacopsychiatry, 1984, Volume: 17, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adult; Bipolar Disorder; Cortodoxone; Dexamethasone; Female; Humans; Hydr

1984
The psychotropic effects of inhibitors of steroid biosynthesis in depressed patients refractory to treatment.
    Biological psychiatry, 1995, Mar-15, Volume: 37, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aminoglutethimide; Bipolar Disorder; Depressive Disorder; Dose-Respo

1995
Ectopic adrenocorticotropin syndrome with prostatic carcinoma.
    Urology, 1973, Volume: 2, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Gluco

1973