metyrapone has been researched along with Psychotic Disorders in 7 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The metyrapone test was applied to groups of patients suffering from major depressive illness with melancholia, mania or schizophrenia, before and after treatment." | 7.67 | The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984) |
| "The metyrapone test was applied to groups of patients suffering from major depressive illness with melancholia, mania or schizophrenia, before and after treatment." | 3.67 | The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment. ( Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okumura, T | 1 |
| Takayama, S | 1 |
| Nishio, SI | 1 |
| Miyakoshi, T | 1 |
| Noguchi, T | 1 |
| Kobayashi, T | 1 |
| Fukushima, T | 1 |
| Sekiguchi, N | 1 |
| Otsuki, T | 1 |
| Komatsu, M | 1 |
| Koizumi, T | 1 |
| Hui, X | 1 |
| Zhou, CH | 1 |
| Wang, MW | 1 |
| Myhill, PC | 1 |
| Sillars, BA | 1 |
| Starkstein, S | 1 |
| Annus, T | 1 |
| Yeap, BB | 1 |
| Perini, GI | 2 |
| Fava, GA | 2 |
| Morphy, MA | 2 |
| Carson, SW | 2 |
| Molnar, G | 2 |
| Jusko, WJ | 2 |
| Ghadirian, AM | 1 |
| Engelsmann, F | 1 |
| Dhar, V | 1 |
| Filipini, D | 1 |
| Keller, R | 1 |
| Chouinard, G | 1 |
| Murphy, BE | 1 |
| Newmark, SR | 1 |
| Dluhy, RG | 1 |
| Bennett, AH | 1 |
2 reviews available for metyrapone and Psychotic Disorders
| Article | Year |
|---|---|
ACTH-producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review.
Topics: Adrenocorticotropic Hormone; Adult; Female; Humans; Metyrapone; Multiple Pulmonary Nodules; Neuroend | 2019 |
Glucocorticoid receptor and treatment of psychotic major depression.
Topics: Animals; Brain; Dehydroepiandrosterone; Depressive Disorder, Major; Humans; Metyrapone; Mifepristone | 2005 |
5 other studies available for metyrapone and Psychotic Disorders
| Article | Year |
|---|---|
Reduction in salivary cortisol concentration correlates with resolution of psychosis in Cushing's syndrome.
Topics: Antimetabolites; Cushing Syndrome; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Psychotic | 2008 |
The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment.
Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Cortodoxone; Depressive | 1984 |
The metyrapone test in manic patients and healthy subjects.
Topics: 17-Hydroxycorticosteroids; Adult; Bipolar Disorder; Cortodoxone; Dexamethasone; Female; Humans; Hydr | 1984 |
The psychotropic effects of inhibitors of steroid biosynthesis in depressed patients refractory to treatment.
Topics: Adrenal Cortex Hormones; Adult; Aminoglutethimide; Bipolar Disorder; Depressive Disorder; Dose-Respo | 1995 |
Ectopic adrenocorticotropin syndrome with prostatic carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Gluco | 1973 |