Page last updated: 2024-10-31

metyrapone and Proteinuria

metyrapone has been researched along with Proteinuria in 3 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"In order to elucidate the mechanisms of the antinephritic action of TJ-8014, the effect of this drug on corticosterone release from the adrenal cortex was investigated by using normal rats and rats with original-type anti-GBM nephritis."3.67Studies on antinephritic effect of TJ-8014, a new Japanese herbal medicine, and its mechanisms (2): Effect on the release of corticosterone from adrenal glands. ( Hattori, T; Ito, M; Nagamatsu, T; Suzuki, Y, 1989)
"As phenobarbital treatment in young rats enhanced the symptoms of nephrotoxicity and metyrapone treatment in adult rats decreased the symptoms of nephrotoxicity, age-dependent differences in chromate nephrotoxicity may be linked to an increase in the enzymatic reduction of Cr(VI) with age."1.28Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats. ( Appenroth, D; Bräunlich, H; Friese, KH; Gambaryan, S, 1990)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Appenroth, D1
Gambaryan, S1
Friese, KH1
Bräunlich, H1
Hattori, T1
Nagamatsu, T1
Ito, M1
Suzuki, Y1
Egan, TJ1
Kenny, FM1
Jarrah, A1
Holliday, MA1

Other Studies

3 other studies available for metyrapone and Proteinuria

ArticleYear
Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats.
    Journal of applied toxicology : JAT, 1990, Volume: 10, Issue:3

    Topics: Aging; Animals; Chromates; Chromium; Cromolyn Sodium; Female; Kidney; Kidney Diseases; Kidney Tubule

1990
Studies on antinephritic effect of TJ-8014, a new Japanese herbal medicine, and its mechanisms (2): Effect on the release of corticosterone from adrenal glands.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:1

    Topics: Adrenal Glands; Animals; Basement Membrane; Corticosterone; Drugs, Chinese Herbal; In Vitro Techniqu

1989
Shock as a complication of the nephrotic syndrome.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Blood Proteins; Child; Child, Pr

1967