metyrapone has been researched along with Pituitary Neoplasms in 88 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We wished to develop optimal criteria for interpreting the single-dose overnight metyrapone test and to compare the diagnostic efficiency of the overnight and the standard 6-dose metyrapone tests for the differential diagnosis of ACTH-dependent Cushing's syndrome." | 7.69 | A comparison of the overnight and the standard metyrapone test for the differential diagnosis of adrenocorticotrophin-dependent Cushing's syndrome. ( Avgerinos, PC; Cutler, GB; Nieman, LK; Oldfield, EH, 1996) |
| "18 patients were studied on 21 occasions: three with Cushing's disease without metyrapone treatment prior to IPSS (M-), 11 with Cushing's disease with metyrapone pretreatment (M+), three with ectopic ACTH syndrome, and one with pseudo-Cushing's syndrome." | 7.69 | Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome. ( Atkinson, RL; Cameron, DP; Cuneo, RC; Harper, J; Lee, W; Mitchell, K; Salkield, I; Ward, G, 1997) |
| "Evaluation of single-dose metyrapone tests in children with hypopituitarism; comparison with the prolonged metyrapone and insulin induced hypoglycaemia tests and their relationship with the etiology of hypopituitarism." | 7.65 | Evaluation of single oral dose metyrapone tests in children with hypopituitarism. ( Basmaciogullari, A; Limal, JM; Rappaport, R, 1976) |
| "We wished to develop optimal criteria for interpreting the single-dose overnight metyrapone test and to compare the diagnostic efficiency of the overnight and the standard 6-dose metyrapone tests for the differential diagnosis of ACTH-dependent Cushing's syndrome." | 3.69 | A comparison of the overnight and the standard metyrapone test for the differential diagnosis of adrenocorticotrophin-dependent Cushing's syndrome. ( Avgerinos, PC; Cutler, GB; Nieman, LK; Oldfield, EH, 1996) |
| "18 patients were studied on 21 occasions: three with Cushing's disease without metyrapone treatment prior to IPSS (M-), 11 with Cushing's disease with metyrapone pretreatment (M+), three with ectopic ACTH syndrome, and one with pseudo-Cushing's syndrome." | 3.69 | Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome. ( Atkinson, RL; Cameron, DP; Cuneo, RC; Harper, J; Lee, W; Mitchell, K; Salkield, I; Ward, G, 1997) |
| " In congenital adrenal hyperplasia, plasma ACTH concentrations mirror, together with 17-alpha-hydroxyprogesterone, the extent of ACTH suppression." | 3.67 | Plasma ACTH in diagnosis and control of adrenal disorders. ( Baumann, JB; Eberle, AN; Girard, J, 1986) |
| "Subnormal plasma 11-deoxycortisol (compound S) responses to metyrapone were found in patients with adrenal insufficiency or with Cushing syndrome caused by adrenal tumors and in those receiving long-term glucocorticoid or diphenylhydantoin sodium therapy." | 3.65 | Single-dose metyrapone test: review of a four-year experience. ( Jubiz, W; Meikle, AW; Spiger, M; Tylor, FH; West, CD, 1975) |
| "Evaluation of single-dose metyrapone tests in children with hypopituitarism; comparison with the prolonged metyrapone and insulin induced hypoglycaemia tests and their relationship with the etiology of hypopituitarism." | 3.65 | Evaluation of single oral dose metyrapone tests in children with hypopituitarism. ( Basmaciogullari, A; Limal, JM; Rappaport, R, 1976) |
| "The Metyrapone was given, the morning, in perfusion intravenous of saline serum over 2 hours." | 2.64 | [Changes in plasma level of corticotropin after intravenous injection of metyrapone. Value of this test in pituitary pathology]. ( Gabaude, B; Huguenin, A; Javalet, A; Murie, N, 1977) |
| "Hypercortisolism induced by Cushing disease causes high morbidity and mortality." | 2.48 | New prospects for drug treatment in Cushing disease. ( Barahona Constanzo, MJ; del Pozo Picó, C, 2012) |
| "Cushing's syndrome is a complex endocrine condition with potential serious complications if untreated or inadequately treated." | 2.45 | Drugs in the medical treatment of Cushing's syndrome. ( Schteingart, DE, 2009) |
| "The hypercortisolism is a rare endocrine disease characterized by an autonomous steroid secretion or excessive adrenal stimulation by ACTH." | 1.43 | [Indications and future perspectives in the pharmacological treatment of hypercortisolism]. ( Stigliano, A; Toscano, V, 2016) |
| "A long-term recurrence rate of Cushing's disease ranging from 2%-25% has been reported." | 1.39 | [Predictors of long-term remission after transsphenoidal surgery in Cushing's disease]. ( Abellán Galiana, P; Escrivá, CM; Fajardo Montañana, C; Gómez Vela, J; Lillo, VR; Riesgo Suárez, PA, 2013) |
| "Because TS may cause pituitary insufficiency in some of these patients, early postoperative assessment of pituitary function is essential for appropriate endocrine management." | 1.38 | The use of an early postoperative CRH test to assess adrenal function after transsphenoidal surgery for pituitary adenomas. ( Biermasz, NR; Kokshoorn, NE; Pereira, AM; Rambach, AH; Roelfsema, F; Romijn, JA; Smit, JW, 2012) |
| "Together, these data show that in pituitary disorders the results of the LDT and the HDT are almost identical." | 1.30 | Comparison of low and high dose corticotropin stimulation tests in patients with pituitary disease. ( Bähr, V; Diederich, S; Mayenknecht, J; Oelkers, W; Plöckinger, U, 1998) |
| "In vitro perifusion of the pituitary adenoma obtained by surgery revealed that o-CRF also stimulated ACTH and beta-EP release in a dose-responsive manner (10(-9)M 10(-5)M) and that dopamine suppressed their basal secretion." | 1.27 | Effect of ovine corticotrophin releasing factor, bromocriptine, and dopamine on release of ACTH and beta-endorphin in a patient with Cushing's disease. ( Fujita, T; Hirata, Y; Nakashima, H; Tomita, M; Uchihashi, M, 1985) |
| "A 52-year-old woman experienced hypoadrenalism (mean 8 AM plasma cortisol level, 3." | 1.26 | Stress-induced cortisol release in hypothalamic hypoadrenalism. ( Glass, AR; Smith, CE, 1979) |
| "Six nonadrenalectomized patients with pituitary tumors showed similar abnormalities of ACTH regulation." | 1.25 | Studies of ACTH secretion control in 116 cases of Cushing's syndrome. ( Binoux, M; Girard, F; Gourmelen, M; Luton, JP; Raux, MC, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (79.55) | 18.7374 |
| 1990's | 7 (7.95) | 18.2507 |
| 2000's | 4 (4.55) | 29.6817 |
| 2010's | 6 (6.82) | 24.3611 |
| 2020's | 1 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Pivonello, R | 1 |
| Simeoli, C | 1 |
| Di Paola, N | 1 |
| Colao, A | 1 |
| Daniel, E | 1 |
| Aylwin, S | 1 |
| Mustafa, O | 1 |
| Ball, S | 1 |
| Munir, A | 1 |
| Boelaert, K | 1 |
| Chortis, V | 1 |
| Cuthbertson, DJ | 1 |
| Daousi, C | 1 |
| Rajeev, SP | 1 |
| Davis, J | 1 |
| Cheer, K | 1 |
| Drake, W | 1 |
| Gunganah, K | 1 |
| Grossman, A | 1 |
| Gurnell, M | 1 |
| Powlson, AS | 1 |
| Karavitaki, N | 1 |
| Huguet, I | 1 |
| Kearney, T | 1 |
| Mohit, K | 1 |
| Meeran, K | 1 |
| Hill, N | 1 |
| Rees, A | 1 |
| Lansdown, AJ | 1 |
| Trainer, PJ | 1 |
| Minder, AE | 1 |
| Newell-Price, J | 1 |
| Stigliano, A | 1 |
| Toscano, V | 1 |
| Schteingart, DE | 1 |
| Bronstein, MD | 1 |
| Paraiba, DB | 1 |
| Jallad, RS | 1 |
| Kokshoorn, NE | 1 |
| Romijn, JA | 1 |
| Roelfsema, F | 1 |
| Rambach, AH | 1 |
| Smit, JW | 1 |
| Biermasz, NR | 1 |
| Pereira, AM | 1 |
| Barahona Constanzo, MJ | 1 |
| del Pozo Picó, C | 1 |
| Abellán Galiana, P | 1 |
| Fajardo Montañana, C | 1 |
| Riesgo Suárez, PA | 1 |
| Gómez Vela, J | 1 |
| Escrivá, CM | 1 |
| Lillo, VR | 1 |
| BRUNET, J | 1 |
| SAUCIER, G | 1 |
| RODRIGUEZDORESTE, OL | 1 |
| MAS, S | 1 |
| RICHMOND, L | 1 |
| CHAPPELL, J | 1 |
| CLEVELAND, WW | 1 |
| MAGGIOLO, J | 1 |
| CASTIGLIONI, CA | 1 |
| OLIVIERI, E | 1 |
| JENKINS, JS | 3 |
| ELKINGTON, SG | 2 |
| HADDOCK, L | 1 |
| RODRIGUEZ, O | 1 |
| KRIEGER, DT | 1 |
| KOLODNY, H | 1 |
| KRIEGER, HP | 1 |
| KEPES, JJ | 1 |
| REECE, CA | 1 |
| OXLEY, DK | 1 |
| KUMAGAI, H | 1 |
| Miyoshi, T | 1 |
| Otsuka, F | 1 |
| Suzuki, J | 1 |
| Inagaki, K | 1 |
| Takeda, M | 1 |
| Kano, Y | 1 |
| Yamashita, T | 1 |
| Ogura, T | 1 |
| Date, I | 1 |
| Tanaka, Y | 1 |
| Hashimoto, K | 1 |
| Makino, H | 1 |
| Streeten, DH | 2 |
| Anderson, GH | 1 |
| Dalakos, TG | 1 |
| Seeley, D | 1 |
| Mallov, JS | 1 |
| Eusebio, R | 1 |
| Sunderlin, FS | 2 |
| Badawy, SZ | 2 |
| King, RB | 1 |
| Gogel, EL | 1 |
| Salber, PR | 1 |
| Tyrrell, JB | 1 |
| Rosenblum, ML | 1 |
| Findling, JW | 1 |
| Fachnie, JD | 1 |
| Zafar, MS | 1 |
| Mellinger, RC | 2 |
| Chason, JL | 1 |
| Kahkonen, DM | 1 |
| de Lange, WE | 1 |
| Sluiter, WJ | 1 |
| Pratt, JJ | 1 |
| Doorenbos, H | 1 |
| Thorén, M | 1 |
| Ajne, M | 1 |
| Hall, K | 1 |
| Wetterberg, L | 1 |
| Hiramatsu, R | 1 |
| Shimada, T | 1 |
| Sato, T | 1 |
| Notman, DD | 1 |
| Springer, JM | 1 |
| Omar, MM | 1 |
| Marshall, LD | 1 |
| Zgliczyński, S | 1 |
| Laws, ER | 1 |
| Abboud, CF | 1 |
| Kern, EB | 1 |
| Suda, T | 1 |
| Tozawa, F | 1 |
| Dobashi, I | 1 |
| Horiba, N | 1 |
| Ohmori, N | 1 |
| Yamakado, M | 1 |
| Yamada, M | 1 |
| Demura, H | 1 |
| Phlipponneau, M | 1 |
| Lenne, F | 1 |
| Proeschel, MF | 1 |
| Girard, F | 3 |
| Luton, JP | 4 |
| Bertagna, X | 1 |
| Fujiwara, I | 1 |
| Igarashi, Y | 1 |
| Ogawa, E | 1 |
| Avgerinos, PC | 1 |
| Nieman, LK | 1 |
| Oldfield, EH | 1 |
| Cutler, GB | 1 |
| Cuneo, RC | 1 |
| Lee, W | 1 |
| Harper, J | 1 |
| Mitchell, K | 1 |
| Ward, G | 1 |
| Atkinson, RL | 1 |
| Salkield, I | 1 |
| Cameron, DP | 1 |
| Mayenknecht, J | 1 |
| Diederich, S | 1 |
| Bähr, V | 1 |
| Plöckinger, U | 1 |
| Oelkers, W | 1 |
| Courtney, CH | 1 |
| McAllister, AS | 1 |
| McCance, DR | 1 |
| Hadden, DR | 1 |
| Leslie, H | 1 |
| Sheridan, B | 1 |
| Atkinson, AB | 1 |
| Shimizu, C | 1 |
| Yamane, Y | 1 |
| Ishizuka, T | 1 |
| Kijima, H | 1 |
| Takano, K | 1 |
| Takano, A | 1 |
| Kubo, M | 1 |
| Koike, T | 1 |
| Jaquet, P | 1 |
| Grisoli, F | 1 |
| Guibout, M | 1 |
| Lissitzky, JC | 1 |
| Carayon, P | 1 |
| Schnall, AM | 1 |
| Brodkey, JS | 1 |
| Kaufman, B | 1 |
| Pearson, OH | 1 |
| Raux, MC | 1 |
| Binoux, M | 2 |
| Gourmelen, M | 1 |
| Murie, N | 1 |
| Gabaude, B | 1 |
| Javalet, A | 1 |
| Huguenin, A | 1 |
| Feldman, JM | 1 |
| Plonk, JW | 1 |
| Glass, AR | 1 |
| Smith, CE | 1 |
| Staub, JJ | 1 |
| Noelpp, B | 1 |
| Turpin, G | 1 |
| Heshmati, HM | 1 |
| Roger, M | 1 |
| Legrand, S | 1 |
| Guillemant, S | 1 |
| de Gennes, JL | 1 |
| Liddle, GW | 1 |
| Rorstad, O | 1 |
| Urtasun, R | 1 |
| Watanabe, M | 2 |
| Spiger, M | 1 |
| Jubiz, W | 1 |
| Meikle, AW | 2 |
| West, CD | 2 |
| Tylor, FH | 1 |
| Limal, JM | 1 |
| Basmaciogullari, A | 1 |
| Rappaport, R | 1 |
| Kato, Y | 1 |
| Howlett, TA | 2 |
| Plowman, PN | 1 |
| Wass, JA | 1 |
| Rees, LH | 2 |
| Jones, AE | 1 |
| Besser, GM | 1 |
| Fuhrman, SA | 1 |
| Beyer, HS | 1 |
| Bantle, JP | 1 |
| Mariash, CN | 1 |
| Steffes, MW | 1 |
| Seljeskog, EL | 1 |
| Oppenheimer, JH | 1 |
| Nakashima, H | 1 |
| Hirata, Y | 1 |
| Uchihashi, M | 1 |
| Tomita, M | 1 |
| Fujita, T | 1 |
| Laurberg, P | 1 |
| Møller, J | 1 |
| Husager, L | 1 |
| Weeke, J | 1 |
| Carpenter, PC | 1 |
| Girard, J | 1 |
| Eberle, AN | 1 |
| Baumann, JB | 1 |
| Salvador, J | 1 |
| Wilson, DW | 1 |
| Harris, PE | 1 |
| Peters, JR | 1 |
| Edwards, C | 1 |
| Foord, SM | 1 |
| Dieguez, C | 1 |
| Hall, R | 1 |
| Scanlon, MF | 1 |
| Else, W | 1 |
| Mautalen, CA | 1 |
| Buckell, M | 1 |
| Isidori, A | 1 |
| Frajese, G | 1 |
| Dondero, F | 1 |
| Mayama, T | 1 |
| Tucci, JR | 1 |
| Espiner, EA | 1 |
| Jagger, PI | 1 |
| Lauler, DP | 1 |
| Thorn, GW | 1 |
| Rinne, UK | 1 |
| French, FS | 1 |
| Macfie, JA | 1 |
| Baggett, B | 1 |
| Williams, TF | 1 |
| Van Wyk, JJ | 1 |
| Lundberg, PO | 3 |
| Wide, L | 3 |
| Bates, RW | 1 |
| Garrison, MM | 1 |
| Bricaire, H | 1 |
| Nieshlag, E | 1 |
| Kroeger, FJ | 2 |
| Wombacher, H | 2 |
| Overzier, C | 2 |
| Imura, H | 1 |
| Matsukura, S | 1 |
| Nishida, S | 1 |
| Nakajima, T | 1 |
| Gourmelen-Combourieu, M | 1 |
| Pham-Huu-Trung, MT | 1 |
| Spark, RF | 1 |
| Nieschlag, E | 1 |
| Faglia, G | 2 |
| Ambrosi, B | 2 |
| Beck-Peccoz, P | 2 |
| Giovanelli, M | 1 |
| Travaglini, P | 1 |
| Haigler, ED | 1 |
| Hershman, JM | 1 |
| Meador, CK | 1 |
| Uozumi, T | 1 |
| Mori, S | 1 |
| Takimoto, N | 1 |
| Mogami, H | 1 |
| Lagerquist, LG | 1 |
| Tyler, FH | 1 |
| Gates, RB | 1 |
| Friesen, H | 1 |
| Samaan, NA | 1 |
| Osterman, PO | 1 |
| Rodrigo Sáez, LR | 1 |
| Feurle, G | 1 |
| Reisert, PM | 1 |
| Emrich, D | 1 |
| König, A | 1 |
| Bushe, KA | 1 |
| Tada, T | 1 |
| Gómez-Vargas, E | 1 |
| Zárate, A | 1 |
| Karchmer, S | 1 |
| Domínguez, H | 1 |
| Mills, IH | 1 |
| Wilson, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolic, Pressor and Neuropsychological Effects of Metyrapone Treatment in Patients With Hypercortisolism[NCT05255900] | 20 participants (Anticipated) | Observational | 2022-04-28 | Recruiting | |||
| Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma[NCT03145285] | Phase 2 | 10 participants (Anticipated) | Interventional | 2017-04-18 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for metyrapone and Pituitary Neoplasms
| Article | Year |
|---|---|
Cushing's disease: adrenal steroidogenesis inhibitors.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Female; Humans; Hypokalemia; Ketoconazole; Male; Mety | 2022 |
Drugs in the medical treatment of Cushing's syndrome.
Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Antiparkinson Agents; Cabergoline; Cushing Sy | 2009 |
Management of pituitary tumors in pregnancy.
Topics: Dopamine Agonists; Female; Humans; Ketoconazole; Metyrapone; Pituitary Neoplasms; Pregnancy; Pregnan | 2011 |
New prospects for drug treatment in Cushing disease.
Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trial | 2012 |
Normal and abnormal function of the hypothalamic-pituitary-adrenocortical system in man.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adolescent; Adrenocorticotropic Hormone | 1984 |
The relationship between the pineal gland and the pituitary--adrenal axis in health, endocrine and psychiatric conditions.
Topics: Adenoma; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Syndr | 1983 |
[Modern methods for ambulatory evaluation of hypothalamic-pituitary function].
Topics: Adrenocorticotropic Hormone; Clomiphene; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Hum | 1979 |
[Drug therapy of pituitary tumors].
Topics: Bromocriptine; Cushing Syndrome; Cyproheptadine; Female; Humans; Male; Metyrapone; Octreotide; Pitui | 1991 |
Appropriate laboratory testing in the screening and work-up of Cushing's syndrome.
Topics: Adenoma; Adrenocorticotropic Hormone; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethaso | 1988 |
Is it possible to diagnose pituitary-dependent Cushing's disease?
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hor | 1985 |
Cushing's syndrome: update of diagnosis and management.
Topics: Adenoma; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushin | 1986 |
[ACTH--how to read its figures].
Topics: Addison Disease; Adrenocorticotropic Hormone; Biological Assay; Blood Chemical Analysis; Circadian R | 1971 |
3 trials available for metyrapone and Pituitary Neoplasms
| Article | Year |
|---|---|
A comparison of pituitary-adrenal responses to corticotropin-releasing hormone, hypoglycaemia and metyrapone in children with brain tumours and growth hormone deficiency.
Topics: Adolescent; Adrenocorticotropic Hormone; Brain Neoplasms; Child; Child, Preschool; Corticotropin-Rel | 1995 |
[Changes in plasma level of corticotropin after intravenous injection of metyrapone. Value of this test in pituitary pathology].
Topics: Adrenocorticotropic Hormone; Adult; Clinical Trials as Topic; Cushing Syndrome; Drug Tolerance; Huma | 1977 |
Vasopressin test in central nervous system-pituitary disorders.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adrenal Glands; Adrenocorticotropic Hor | 1968 |
73 other studies available for metyrapone and Pituitary Neoplasms
| Article | Year |
|---|---|
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
[Indications and future perspectives in the pharmacological treatment of hypercortisolism].
Topics: Adenoma; Cushing Syndrome; Humans; Hydrocortisone; Italy; Ketoconazole; Metyrapone; Pituitary Neopla | 2016 |
The use of an early postoperative CRH test to assess adrenal function after transsphenoidal surgery for pituitary adenomas.
Topics: Adenoma; Adolescent; Adrenal Insufficiency; Adult; Aged; Aged, 80 and over; Corticotropin-Releasing | 2012 |
[Predictors of long-term remission after transsphenoidal surgery in Cushing's disease].
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenal Insufficiency; Adrenocorticotropic Ho | 2013 |
[Clinical experience with a test of pituitary reserve].
Topics: 17-Hydroxycorticosteroids; Adult; Child; Diabetes Insipidus; Female; Humans; Hypopituitarism; Male; | 1963 |
[STUDY OF PITUITARY FUNCTION WITH THE NEW METHOPYRAPONE TEST].
Topics: Achondroplasia; Adolescent; Adrenal Cortex Hormones; Craniopharyngioma; Diagnosis, Differential; Dwa | 1963 |
RESPONSE OF CHILDREN TO METHOPYRAPONE (METOPIRONE).
Topics: Adolescent; Adrenal Cortex Hormones; Brain Diseases; Child; Craniopharyngioma; Craniosynostoses; Dia | 1964 |
[EXPLORATION OF THE ACTH HYPOPHYSEAL RESERVE WITH METOPIRONE IN DIFFERENT ENDOCRINOPATHIES].
Topics: 17-Ketosteroids; Acromegaly; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Clinical Lab | 1963 |
METYRAPONE AND PYROGEN IN THE ASSESSMENT OF PITUITARY-ADRENAL FUNCTION AFTER REMOVAL OF PITUITARY ADENOMA.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenocorticotropic Hormone; Blood; Hypopituitarism; Ketones; Me | 1964 |
"THE USE OF SU 4885 (METHOPYRAPONE) TO STUDY THE PITUITARY ACTH RESERVE IN PATIENTS WITH SHEEHAN'S DISEASE AND PITUITARY TUMORS".
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Biomedical Research; Clinic | 1964 |
METHOPYRAPONE TESTS IN HYPOTHALAMIC-PITUITARY DISEASE.
Topics: Adrenocorticotropic Hormone; Brain Diseases; Brain Neoplasms; Diagnosis; Humans; Hypothalamic Diseas | 1964 |
CENTRAL PONTINE MYELINOLYSIS IN A 7-YEAR-OLD BOY.
Topics: Child; Craniopharyngioma; Dehydration; Demyelinating Diseases; Humans; Ketones; Male; Metyrapone; Mi | 1965 |
[STUDIES ON THE DIAGNOSTIC USE OF METOPIRONE (11-BETA-HYDROXYLASE INHIBITOR) IN DISEASES OF THE PITUITARY AND ADRENAL CORTEX].
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Blo | 1964 |
Periodic secretion of adrenocorticotropin in a patient with Cushing's disease manifested during pregnancy.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Female; Humans; Hydroc | 2005 |
Cushing's disease in a patient with a 'nonfunctioning' pituitary tumor. Spontaneous development and remission.
Topics: Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Femal | 1983 |
Pituitary carcinoma mimics the ectopic adrenocorticotropin syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Dexamethasone; Diagnosis, D | 1980 |
Plasma 11-deoxycortisol, androstenedione, testosterone and ACTH in comparison with the urinary excretion of tetrahydro-11-deoxycortisol as indices of the pituitary-adrenal response to oral metyrapone.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Androstenedione; Co | 1980 |
Plasma pattern of immunoreactive ACTH in normal man and in patients with Nelson's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; Chromatography, Gel; Cross Reactions; Female; Humans; Hydrocorti | 1981 |
A case of dexamethasone non-suppressible Cushing's disease hardly differentiated from ectopic ACTH syndrome.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Diagnos | 1983 |
Hypothalamic-pituitary function following bromocriptine therapy in patients with prolactinomas.
Topics: Adenoma; Adult; Bromocriptine; Female; Humans; Hypothalamo-Hypophyseal System; Infertility, Female; | 1982 |
[Cushing's syndrome: metyrapone therapy as a preparation for selective trans-sphenoidal adenomectomy].
Topics: Adenoma; Adolescent; Adult; Cushing Syndrome; Female; Humans; Male; Metyrapone; Middle Aged; Pituita | 1982 |
Perioperative management of patients with pituitary microadenoma.
Topics: Adenoma; Female; Humans; Hypopituitarism; Male; Metyrapone; Microsurgery; Pituitary Neoplasms; Posto | 1980 |
Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Arginine | 1993 |
Plasma immunoreactive joining peptide in man: a new marker of proopiomelanocortin processing and corticotroph function.
Topics: Adrenocorticotropic Hormone; Adult; beta-Lipotropin; Chromatography, Gel; Circadian Rhythm; Dexameth | 1993 |
A comparison of the overnight and the standard metyrapone test for the differential diagnosis of adrenocorticotrophin-dependent Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Cortodoxone; Cushing Syndrome; Humans; Hydrocortisone; Metyrapone; Pilot Pro | 1996 |
Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Cortodoxone; Cushin | 1997 |
Comparison of low and high dose corticotropin stimulation tests in patients with pituitary disease.
Topics: Adult; Aged; Aged, 80 and over; Corticotropin-Releasing Hormone; Cosyntropin; Female; Humans; Hydroc | 1998 |
The insulin hypoglycaemia and overnight metyrapone tests in the assessment of the hypothalamic-pituitary-adrenal axis following pituitary surgery.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cortodoxone; Female; Follow-Up Studies; Humans; H | 2000 |
Involvement of the cholinergic pathway in the pathogenesis of pituitary Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenocorticotropic Hormone; Atropine; Choline; | 2001 |
Prolactin secreting tumors. Endocrine status before and after surgery in 33 women.
Topics: Adenoma; Arginine; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; | 1978 |
Pituitary function after removal of pituitary microadenomas in Cushing's disease.
Topics: 17-Ketosteroids; Adenoma; Adult; Cushing Syndrome; Follicle Stimulating Hormone; Humans; Hydrocortis | 1978 |
Studies of ACTH secretion control in 116 cases of Cushing's syndrome.
Topics: Adrenal Gland Diseases; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Biological Assay; Cushi | 1975 |
Effect of hyperprolactinemia on pituitary-adrenal function.
Topics: Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Brain Diseases; Female; Humans; Hypothalam | 1978 |
Stress-induced cortisol release in hypothalamic hypoadrenalism.
Topics: 17-Hydroxycorticosteroids; Adrenal Insufficiency; Adrenocorticotropic Hormone; Circadian Rhythm; Cra | 1979 |
[Adrenocortical function in hyperprolactinemia. The study of glucocorticoids, mineralocorticoids and androgens in chronic and acute hyperprolactinemias (author's transl)].
Topics: Acute Disease; Adenoma; Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Chronic Disease; Fem | 1979 |
Cushing's syndrome.
Topics: Adenoma; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Humans; Metyrapone; Pitui | 1977 |
Variation in response to dexamethasone of a patient with Cushing's syndrome.
Topics: Adenoma, Chromophobe; Adult; Cortodoxone; Cushing Syndrome; Dexamethasone; Female; Humans; Hydrocort | 1976 |
Single-dose metyrapone test: review of a four-year experience.
Topics: Adenoma, Chromophobe; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Glands; | 1975 |
Evaluation of single oral dose metyrapone tests in children with hypopituitarism.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Arginine; Blood Glucose; Child; Cortodoxone; Craniopha | 1976 |
Megavoltage pituitary irradiation in the management of Cushing's disease and Nelson's syndrome: long-term follow-up.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Cushing Syndrome; Female; Follow-Up Studies; H | 1989 |
Use of the dexamethasone-adrenocorticotropin test to assess the requirement for continued glucocorticoid replacement therapy after pituitary surgery.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Cortodoxone; Dexamethasone; Female; Glucocorticoids; Human | 1985 |
Effect of ovine corticotrophin releasing factor, bromocriptine, and dopamine on release of ACTH and beta-endorphin in a patient with Cushing's disease.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Animals; beta-Endorphin; Bromocriptine; Corticotropin-R | 1985 |
Evaluation of pituitary-adrenal function after pituitary surgery.
Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cortodoxone; Cranio | 1985 |
Plasma ACTH in diagnosis and control of adrenal disorders.
Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adre | 1986 |
Relationships between the circadian rhythms of TSH, prolactin and cortisol in surgically treated microprolactinoma patients.
Topics: Adult; Circadian Rhythm; Female; Humans; Hydrocortisone; Metyrapone; Pituitary Gland; Pituitary Neop | 1985 |
Pituitary-adrenal function tests in patients with untreated pituitary tumours.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cerebral Ventriculography; Female; Humans; Hydroc | 1968 |
Nonsuppressible adrenocortical function in a patient with untreated acromegaly.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adrenal Glands; Adrenocorticotropic Hormone; | 1965 |
Endocrine function following treatment of pituitary adenoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenocorticotropic Hormone; Adult; Basal Metab | 1967 |
[Functional evaluation of the pituitary gland with the metyrapone test and determination of ACTH in the blood].
Topics: Acromegaly; Adrenal Insufficiency; Adrenocorticotropic Hormone; Cushing Syndrome; Humans; Hypopituit | 1967 |
[Clinical studies on the adrenocorticotropic hormone. II. Studies on the mechanism of pituitary corticotropin secretion with synthetic lysine vasopressin].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Brain Neoplasms; Ci | 1968 |
Vasopressin in the evaluation of pituitary-adrenal function.
Topics: Acromegaly; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Anorex | 1968 |
Cushing's syndrome with a paradoxical response to dexamethasone.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Basophil; Adrenalectomy; Adrenocortical Hyperfu | 1969 |
Vasopressin test in tumours of the sellar region.
Topics: Adenoma, Acidophil; Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Aged; Diagnosis, Diffe | 1969 |
Delay of hormonally induced diabetes by amino-glutethimide and metyrapone in partially pancreatectomized rats bearing transplantable pituitary tumors. Concomitant failure to prevent splanchnomegaly.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonv | 1970 |
[Poly-micro-adenomatosis in Cushing's syndrome].
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndr | 1970 |
[Endocrinological diagnosis of pituitary tumors].
Topics: Adenoma, Acidophil; Adenoma, Chromophobe; Adult; Aged; Female; Growth Hormone; Humans; Male; Metyrap | 1971 |
[Pituitary function test using synthetic lysine-8-vasopressin--comparison with metopirone test and insulin stress test].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anorexia Nervosa; Craniopharyngioma; Cushing S | 1971 |
[Study of plasma ACTH in 100 human lysine-vasopressin tests].
Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotro | 1971 |
Simplified assessment of pituitary-adrenal reserve. Measurement of serum 11-deoxycortisol and cortisol after metyrapone.
Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Biotransformation; Child; Child, P | 1971 |
[Human growth hormone estimations in the differential diagnosis of chromophobe and eosinophil pituitary adenomas].
Topics: Adenoma, Acidophil; Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Aged; Female; Growth H | 1971 |
Disorders of growth hormone and corticotropin regulation in patients with empty sella.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult | 1973 |
The response to TRH, LH-RH, metyrapone and vasopressin in patients with hypothalamo-pituitary disorders.
Topics: Acromegaly; Adenoma, Acidophil; Adenoma, Chromophobe; Adult; Brain Neoplasms; Craniopharyngioma; Dia | 1973 |
Hypothalamic-pituitary-adrenal function in patients with pituitary tumours.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adolescent; Adrenal Glands; Adrenocorti | 1973 |
Pituitary gigantism. A case report and review.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Antigens; Blood | 1973 |
[Endocrinological evaluation of sellar and suprasellar tumor cases --the first report-- on preoperative pituitary function (author's transl)].
Topics: Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Brain Neoplasms; Child; Chordoma; Craniopha | 1974 |
Cushing's disease with cure by resection of a pituitary adenoma. Evidence against a primary hypothalamic defect.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cushing Syndrome; Depression, Chemica | 1974 |
Inappropriate lactation and amenorrhoea: pathological and diagnostic considerations.
Topics: Adolescent; Adult; Amenorrhea; Arginine; Autopsy; Blood Glucose; Clomiphene; Estrogens; Female; Gona | 1973 |
The level and circadian rhythm of plasma free 11-hydroxycorticoids in patients with localized intracranial processes, especially of the sellar region.
Topics: 11-Hydroxycorticosteroids; Adult; Brain Diseases; Circadian Rhythm; Female; Humans; Hydrocortisone; | 1973 |
[Current aspects of the metopirone (SU-4885) test].
Topics: Administration, Oral; Humans; Injections, Intravenous; Metyrapone; Pituitary Diseases; Pituitary Neo | 1973 |
[Clinical and endocrinologic diagnosis of pituitary and suprasellar tumors].
Topics: Acromegaly; Adenoma, Chromophobe; Craniopharyngioma; Female; Headache; Humans; Hypogonadism; Insulin | 1970 |
[Clinical studies on urinary 17-ketogenic steroid fractions. 3. SU-4885 test in normal subjects and the patients with various endocrine disorders].
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland N | 1968 |
[Forbes-Albright syndrome and the pituitary reserve. Study by the methopyrone test].
Topics: Adult; Amenorrhea; Female; Humans; Kidney Function Tests; Lactation Disorders; Metyrapone; Pituitary | 1968 |
Endocrine studies in women with secondary amenorrhoea.
Topics: Adolescent; Adult; Amenorrhea; Anorexia Nervosa; Basal Metabolism; Female; Gonadotropins; Humans; Io | 1969 |