metyrapone has been researched along with Pituitary Diseases in 94 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Pituitary Diseases: Disorders involving either the ADENOHYPOPHYSIS or the NEUROHYPOPHYSIS. These diseases usually manifest as hypersecretion or hyposecretion of PITUITARY HORMONES. Neoplastic pituitary masses can also cause compression of the OPTIC CHIASM and other adjacent structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of the low dose (1 microgram) ACTH stimulation test in the evaluation of patients with pituitary diseases was systematically assessed by relating its results to those obtained on gold standard tests of hypothalamo-pituitary-adrenal (HPA) reserve, such as insulin-induced hypoglycemia or a metyrapone challenge." | 3.69 | The role of the low dose (1 microgram) adrenocorticotropin test in the evaluation of patients with pituitary diseases. ( Apter, C; Grazas, N; Jaffe, A; Stern, N; Tordjman, K, 1995) |
| " Serum deoxycorticosterone rose in healthy subjects upon injection of ACTH, after induction of insulin hypoglycemia and after administration of metyrapone, while the rise was absent or blunted in patients with Addison's disease and in patients with pituitary failure." | 3.65 | Radioimmunoassay of serum deoxycorticosterone: normal values and changes of serum deoxycorticosterone after adrenal stimulation. ( Harendt, H; Oelkers, W; Schöneshöfer, M, 1975) |
| "The Metyrapone was given, the morning, in perfusion intravenous of saline serum over 2 hours." | 2.64 | [Changes in plasma level of corticotropin after intravenous injection of metyrapone. Value of this test in pituitary pathology]. ( Gabaude, B; Huguenin, A; Javalet, A; Murie, N, 1977) |
| "Metyrapone (30 mg/kg) was administered orally at 2300 h and blood was sampled at 0830 h the following morning for 11-deoxycortisol." | 1.31 | The low dose ACTH stimulation test is less sensitive than the overnight metyrapone test for the diagnosis of secondary hypoadrenalism. ( Attenborough, S; Coetzer, E; Kinvig, S; Kinvig, T; Parolis, G; Peter, D; Soule, S; Van Zyl Smit, C, 2000) |
| "Together, these data show that in pituitary disorders the results of the LDT and the HDT are almost identical." | 1.30 | Comparison of low and high dose corticotropin stimulation tests in patients with pituitary disease. ( Bähr, V; Diederich, S; Mayenknecht, J; Oelkers, W; Plöckinger, U, 1998) |
| " S with an ACTH-cortisol dose-response curve obtained in normal subjects shows that subnormal ACTH responses after metyrapone in the range between 13 and 33 pmol/L still generate normal comp." | 1.29 | Pituitary function tests: comparison of ACTH and 11-deoxy-cortisol responses in the metyrapone test and with the insulin hypoglycemia test. ( Bähr, V; Exner, P; Oelkers, PW; Steiner, H, 1994) |
| "The melatonin secretion was studied in 10 patients, and increased significantly in 8/10 during and in one after the Metyrapone administration." | 1.26 | Melatonin and corticosteroid response to metyrapone in patients with pituitary disease. ( Brismar, K; Werner, S; Wetterberg, L, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 86 (91.49) | 18.7374 |
| 1990's | 4 (4.26) | 18.2507 |
| 2000's | 2 (2.13) | 29.6817 |
| 2010's | 1 (1.06) | 24.3611 |
| 2020's | 1 (1.06) | 2.80 |
| Authors | Studies |
|---|---|
| Nemoto, T | 1 |
| Nakakura, T | 1 |
| Kakinuma, Y | 1 |
| Ismail, AA | 1 |
| GOLD, EM | 1 |
| KENT, JR | 1 |
| FORSHAM, PH | 1 |
| HENKE, WJ | 1 |
| DOE, RP | 1 |
| JACOBSON, ME | 1 |
| BISSELL, GW | 1 |
| SCOTT, AL | 1 |
| FARNSWORTH, WE | 1 |
| WINKLER, I | 1 |
| BIERICH, JR | 2 |
| ECKLER, E | 2 |
| SCHOENBERG, D | 2 |
| COUTINHO, JS | 1 |
| UBATUBA, A | 2 |
| LEITE, CA | 2 |
| UBATUBA, F | 2 |
| STEVENSON, C | 1 |
| BARZELATTO, J | 1 |
| PINEDA, G | 1 |
| SANDOVAL, A | 1 |
| PLAGER, JE | 1 |
| BRAY, GA | 1 |
| JACKSON, JE | 1 |
| BRUNET, J | 1 |
| SAUCIER, G | 1 |
| CODACCIONI, JL | 1 |
| BOYER, J | 1 |
| GARRIGUES, JC | 1 |
| VAGUE, J | 1 |
| de COUTINHO, J | 1 |
| SPRUNT, JG | 1 |
| BROWNIE, AC | 1 |
| KINNEAR, JS | 1 |
| KAPLAN, NM | 2 |
| POMMATAU, E | 1 |
| POULAIN, S | 1 |
| COLON, J | 1 |
| BERTRAND, J | 2 |
| OLLAGNON, C | 1 |
| SAEZ, JM | 1 |
| FOREST, M | 1 |
| ROUX, H | 1 |
| RACADOT, J | 1 |
| DITZEL, J | 1 |
| HANSEN, PF | 1 |
| RISKAER, N | 1 |
| SCHNEIDER, PB | 1 |
| FERRARI, E | 3 |
| MAZZI, C | 2 |
| PIOTTI, LE | 3 |
| DeANDRADE, JR | 1 |
| BOSCHERINI, B | 1 |
| FISCHETTI, M | 1 |
| KLEIN, JJ | 1 |
| OSSERMAN, KE | 1 |
| GENOVA, R | 1 |
| OLIVI, O | 1 |
| BENATTI, C | 1 |
| PIETRAROSSA, N | 1 |
| SOYKA, LF | 1 |
| ZISKIND, A | 1 |
| CRAWFORD, JD | 1 |
| QUENUM, A | 1 |
| ANDERSSON, E | 1 |
| HENDERSON, HR | 1 |
| GILROY, J | 1 |
| MEYER, JS | 1 |
| GOTH, E | 1 |
| GOERGENYI, G | 1 |
| FOEVENYI, J | 1 |
| SZANTO, E | 1 |
| KRIEGER, DT | 1 |
| KOLODNY, H | 1 |
| KRIEGER, HP | 1 |
| TYMCZASOWE, D | 1 |
| JANCHES, M | 3 |
| GOLDBERG, V | 2 |
| SEGAL, L | 1 |
| JAIMOVICH, L | 2 |
| CATOGGIO, PM | 1 |
| DELABALZE, FA | 2 |
| CUSHMAN, P | 2 |
| HILTON, JG | 2 |
| KUMAGAI, H | 1 |
| CATOGGIO, P | 1 |
| MCCULLAGH, EP | 1 |
| FELDSTEIN, MA | 1 |
| TWEED, DC | 1 |
| DOHN, DF | 1 |
| KLEINFELDER, H | 1 |
| HUSMANN, F | 1 |
| ROBEL, P | 1 |
| Dickstein, G | 1 |
| Streeten, DH | 1 |
| Anderson, GH | 1 |
| Dalakos, TG | 1 |
| Seeley, D | 1 |
| Mallov, JS | 1 |
| Eusebio, R | 1 |
| Sunderlin, FS | 1 |
| Badawy, SZ | 1 |
| King, RB | 1 |
| Fachnie, JD | 1 |
| Zafar, MS | 1 |
| Mellinger, RC | 1 |
| Chason, JL | 1 |
| Kahkonen, DM | 1 |
| Feek, CM | 1 |
| Bevan, JS | 1 |
| Ratcliffe, JG | 1 |
| Gray, CE | 1 |
| Blundell, G | 1 |
| Brismar, K | 1 |
| Werner, S | 1 |
| Wetterberg, L | 1 |
| Abou-Samra, AB | 1 |
| Fevre-Montange, M | 1 |
| Pugeat, M | 1 |
| Dechaud, H | 1 |
| Chalendar, D | 1 |
| Estour, B | 1 |
| Tourniaire, J | 1 |
| Nakamura, J | 1 |
| Yakata, M | 1 |
| Tordjman, K | 1 |
| Jaffe, A | 1 |
| Grazas, N | 1 |
| Apter, C | 1 |
| Stern, N | 1 |
| Steiner, H | 1 |
| Bähr, V | 2 |
| Exner, P | 1 |
| Oelkers, PW | 1 |
| de Lange, WE | 2 |
| Sluiter, WJ | 2 |
| Mayenknecht, J | 1 |
| Diederich, S | 1 |
| Plöckinger, U | 1 |
| Oelkers, W | 3 |
| Soule, S | 1 |
| Van Zyl Smit, C | 1 |
| Parolis, G | 1 |
| Attenborough, S | 1 |
| Peter, D | 1 |
| Kinvig, S | 1 |
| Kinvig, T | 1 |
| Coetzer, E | 1 |
| Pelkonen, R | 1 |
| Leisti, S | 1 |
| Perheentupa, J | 1 |
| Kamijo, K | 1 |
| Suzuki, M | 1 |
| Oara, H | 1 |
| Wada, T | 1 |
| Schöneshöfer, M | 1 |
| Harendt, H | 1 |
| Hashimoto, K | 1 |
| Takahara, J | 1 |
| Yunoki, M | 1 |
| Hosoki, H | 1 |
| Ofuji, M | 1 |
| Murie, N | 1 |
| Gabaude, B | 1 |
| Javalet, A | 1 |
| Huguenin, A | 1 |
| Dammacco, F | 1 |
| Rigillo, N | 1 |
| Pentasuglia, N | 1 |
| Zimbalatti, F | 1 |
| Zieger, B | 1 |
| Hubl, W | 1 |
| Büchner, M | 1 |
| Hartzband, PI | 1 |
| Van Herle, AJ | 1 |
| Sorger, L | 1 |
| Cope, D | 1 |
| Suda, T | 1 |
| Tomori, N | 1 |
| Yajima, F | 1 |
| Sumitomo, T | 1 |
| Nakagami, Y | 1 |
| Ushiyama, T | 1 |
| Demura, H | 1 |
| Shizume, K | 1 |
| de Peretti, E | 1 |
| Forest, MG | 1 |
| Loras, B | 1 |
| Morel, Y | 1 |
| David, M | 1 |
| François, R | 1 |
| Pratt, JJ | 1 |
| Wolf, RF | 1 |
| Doorenbos, H | 1 |
| Sasaki, A | 1 |
| Sato, S | 1 |
| Murakami, O | 1 |
| Go, M | 1 |
| Inoue, M | 1 |
| Shimizu, Y | 1 |
| Hanew, K | 1 |
| Andoh, N | 1 |
| Sato, I | 1 |
| Sasano, N | 1 |
| Achenbach, K | 1 |
| Neelon, FA | 1 |
| Goree, JA | 1 |
| Lebovitz, HE | 1 |
| Vivacqua, RJ | 1 |
| Haurani, FI | 1 |
| Erslev, AJ | 1 |
| Martin, MM | 1 |
| De Witt, GF | 1 |
| Abdullah, F | 1 |
| Eravelly, J | 1 |
| Selby, R | 1 |
| Mayama, T | 1 |
| Weber, A | 1 |
| Behrend, H | 1 |
| Gerdes, H | 1 |
| Grant, JM | 1 |
| Yeo, JD | 1 |
| Rinne, UK | 1 |
| Sako, Y | 2 |
| Iwai, K | 1 |
| Imura, H | 2 |
| Honda, H | 1 |
| Tamura, Y | 1 |
| Foltyn, H | 1 |
| Jubiz, W | 1 |
| Meikle, AW | 1 |
| West, CD | 1 |
| Tyler, FH | 1 |
| Laron, Z | 1 |
| Karp, M | 1 |
| Nitzan, M | 1 |
| Pertzelan, A | 1 |
| Toft, H | 1 |
| Buus, O | 1 |
| Nielsen, E | 1 |
| Matsukura, S | 1 |
| Matsuyama, H | 1 |
| Nakai, Y | 1 |
| Spark, RF | 1 |
| Mornex, R | 1 |
| Mallein, R | 1 |
| Bizollon, C | 1 |
| Pellet, H | 1 |
| Durand, H | 1 |
| Fitoussi, R | 1 |
| Zachmann, M | 1 |
| Völlmin, JA | 1 |
| Zagalak, M | 1 |
| Burke, CW | 1 |
| Beardwell, CG | 1 |
| Rodrigo Sáez, LR | 1 |
| Jacobs, HS | 1 |
| Nabarro, JD | 1 |
| Croughs, RJ | 1 |
| Sabeh, G | 1 |
| Alley, RA | 1 |
| Narduzzi, JV | 1 |
| Weir, TF | 1 |
| McGowen, CH | 1 |
| Robbins, TJ | 1 |
| Danowski, TS | 1 |
| Dendukes, R | 1 |
| Socolsky, RC | 1 |
| De Paoli, JC | 1 |
| Amezua, L | 1 |
| De la Balze, F | 1 |
4 reviews available for metyrapone and Pituitary Diseases
| Article | Year |
|---|---|
[METHODOLOGICAL DATA ON THE DYNAMIC EVALUATION OF THE DIENCEPHALON-ANTERIOR PITUITARY-ADRENAL CORTEX SYSTEM].
Topics: Acromegaly; Addison Disease; Adrenal Cortex; Adrenocorticotropic Hormone; Cushing Syndrome; Dexameth | 1964 |
The assessment of the hypothalamo-pituitary-adrenal axis in pituitary disease: are there short cuts?
Topics: Adrenocorticotropic Hormone; Corticotropin-Releasing Hormone; Diagnostic Techniques, Endocrine; Enzy | 2003 |
Normal and abnormal function of the hypothalamic-pituitary-adrenocortical system in man.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adolescent; Adrenocorticotropic Hormone | 1984 |
[Anterior pituitary function test].
Topics: Adrenocorticotropic Hormone; Animals; Biological Assay; Dexamethasone; Growth Hormone; Humans; Insul | 1969 |
2 trials available for metyrapone and Pituitary Diseases
| Article | Year |
|---|---|
[Changes in plasma level of corticotropin after intravenous injection of metyrapone. Value of this test in pituitary pathology].
Topics: Adrenocorticotropic Hormone; Adult; Clinical Trials as Topic; Cushing Syndrome; Drug Tolerance; Huma | 1977 |
Vasopressin test in central nervous system-pituitary disorders.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adrenal Glands; Adrenocorticotropic Hor | 1968 |
88 other studies available for metyrapone and Pituitary Diseases
| Article | Year |
|---|---|
Elevated blood pressure in high-fat diet-exposed low birthweight rat offspring is most likely caused by elevated glucocorticoid levels due to abnormal pituitary negative feedback.
Topics: Animals; Birth Weight; Blood Pressure; Corticosterone; Diet, High-Fat; Feedback, Physiological; Fema | 2020 |
On the diagnosis and investigation of adrenal insufficiency in adults.
Topics: Adrenal Insufficiency; Adult; Diagnostic Techniques, Endocrine; Glucagon; Humans; Hypothalamic Disea | 2010 |
Clinical use of a new diagnostic agent, methopyrapone (SU-4885), in pituitary and adrenocortical disorders.
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Metyrapone; Pituitary Diseases; Pituitary Gland; Pyridines | 1961 |
A test of pituitary reserve utilizing intravenous SU-4885, with a new method for extraction of 11-desoxvcorticosteroids.
Topics: Adrenal Cortex Hormones; Metyrapone; Pituitary Diseases; Pituitary Gland; Pyridines | 1960 |
A preliminary study of the use of 2-methyl-1, 2-bis (3-pyridyl)-1-propanone (SU 4885) as a test of pituitary function in man.
Topics: Metyrapone; Pituitary Diseases; Pituitary Gland; Pituitary Gland, Anterior; Pyridines | 1959 |
[Evaluation of the corticotropic function of the pituitary with metopirone. III. Studies after prolonged treatment with ACTH].
Topics: Adrenocorticotropic Hormone; Humans; Metyrapone; Pituitary Diseases; Pituitary Gland; Pyridines | 1962 |
[Evaluation of the adrenocorticotropic function of the pituitary after administration of compound SU-4885].
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Metyrapone; Pituitary Diseases; Pituitary Gland; Pituit | 1961 |
[Evaluation of the corticotropic function of the pituitary with metopirone. II. Studies after treatment with corticosteroids].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Glucocorticoids; Metyrapone; Pituitary Disease | 1962 |
[SU-4885 in pituitary patients].
Topics: Humans; Metyrapone; Pituitary Diseases; Pituitary Gland; Pyridines | 1962 |
Pituitary-ACTH response to metopirone and endotoxin administration in the dog.
Topics: Adrenocorticotropic Hormone; Animals; Dogs; Endotoxins; Hydrocortisone; Ketones; Metyrapone; Pituita | 1963 |
[Clinical experience with a test of pituitary reserve].
Topics: 17-Hydroxycorticosteroids; Adult; Child; Diabetes Insipidus; Female; Humans; Hypopituitarism; Male; | 1963 |
[Clinical importance of metopirone (SU 4885) in pituitary-adrenal exploration].
Topics: Adrenal Cortex Function Tests; Hypopituitarism; Ketones; Metyrapone; Mineralocorticoid Receptor Anta | 1963 |
[Determination of pituitary reserve in states of chronic malnutrition, using Su-4885. Preliminary report].
Topics: Ketones; Malnutrition; Metyrapone; Nutrition Disorders; Pituitary Diseases; Pituitary Gland; Pyridin | 1962 |
DETECTION OF INCOMPLETE ABLATION AFTER YTTRIUM-90 IMPLANTATION OF PITUITARY.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Gonadotropins; Gonadotropins, Pituitary; Metyr | 1963 |
ASSESSMENT OF PITUITARY ACTH SECRETORY CAPACITY WITH METOPIRONE: 1. INTERPRETATION.
Topics: Acromegaly; Adenoma; Adenoma, Acidophil; Adenoma, Chromophobe; Adrenal Cortex Hormones; Adrenocortic | 1963 |
ASSESSMENT OF PITUITARY ACTH SECRETORY CAPACITY WITH METOPIRONE: II. COMPARISON WITH OTHER TESTS.
Topics: Acromegaly; Adenoma; Adenoma, Chromophobe; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Art | 1963 |
[THE METOPIRONE TEST IN BREAST CANCER OF AN ADVANCED STAGE, BEFORE AND AFTER PITUITARY IMPLANTATION OF YTTRIUM].
Topics: Adrenal Cortex Hormones; Breast Neoplasms; Cortisone; Follicle Stimulating Hormone; Humans; Ketones; | 1963 |
[ADRENO-PITUITARY EXPLORATION IN THE CHILD. VALUE OF THE METOPIRONE TEST COMPARED WITH THE RESPONSE OF BLOOD 17-OHCS IN INSULIN HYPOGLYCEMIA].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood Chemical Analysis; Child; Hy | 1963 |
[THE CYTOLOGICAL ORIGIN OF THE PITUITARY CORTICOTROPIC HORMONE IN THE IMPUBERAL CAT].
Topics: Adrenocorticotropic Hormone; Cats; Histological Techniques; Histology, Comparative; Metyrapone; Mine | 1963 |
PITUITARY-ADRENAL FUNCTION FOLLOWING HYPOPHYSECTOMY IN MAN.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Blood Chemical Analysis; Breast Neoplasms; Gonadotropins; | 1964 |
FALSELY ABNORMAL RESPONSES OF NORMAL SUBJECTS TO THE METOPIRONE (SU-4885) TEST FOR PITUITARY ACTH RESERVE.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Biomedical Research; Ketones; | 1964 |
[PITUITARY CORTICOTROPIN RESERVE AND RESPONSIVENESS IN THE LIDDLE TEST IN DIABETES MELLITUS].
Topics: Adrenocorticotropic Hormone; Diabetes Mellitus; Metabolism; Metyrapone; Pharmacology; Physiology; Pi | 1964 |
PITUITARY-ADRENOCORTICAL RESERVE DURING CORTICOSTEROID THERAPY: A REPORT ON THE METHOPYRAPONE TEST IN TEN PATIENTS TAKING LONG-CONTINUED SMALL DOSES.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Biomedical Research; Met | 1964 |
[THE METOPIRONE TEST IN THE DIFFERENTIAL DIAGNOSIS OF VARIOUS ENDOCRINE DISORDERS OF CHILDHOOD].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Carbohydrate Metabolism; Child; Cu | 1963 |
[PITUITARY CORTICOTROPIN FUNCTIONAL DYNAMICS IN ANOREXIA NERVOSA].
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; A | 1964 |
STUDIES IN MYASTHENIA GRAVIS. PITUITARY-ADRENAL FUNCTION.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Biomedical Re | 1964 |
[PITUITARY-ADRENAL FUNCTION IN INFANTILE ESSENTIAL OBESITY. BIORHYTHM OF PLASMATIC CORTISOL AND THE METOPIRONE TEST].
Topics: Adolescent; Blood Chemical Analysis; Child; Gigantism; Hydrocortisone; Ketones; Metyrapone; Mineralo | 1964 |
TREATMENT OF SHORT STATURE IN CHILDREN AND ADOLESCENTS WITH HUMAN PITUITARY GROWTH HORMONE (RABEN).
Topics: Adolescent; Bone Development; Child; Cortisone; Dwarfism; Dwarfism, Pituitary; Growth; Growth Hormon | 1964 |
[ACTION OF METOPIRONE (SU-4885) ON THE PITUITARY-ADRENOCORTICAL AXIS OF CRICETOMYS GAMBIANUS].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Ascorbic Acid; Histology; Hyperplasia; Hypertrophy; Lip | 1964 |
PITUITARY FUNCTION IN PATIENTS WITH BRONCHIAL ASTHMA MEASURED INDIRECTLY BY METHOPYRAPONE (SU 4885).
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Asthma; Metyrapone; Mineralocorticoid Receptor Antagon | 1964 |
PITUITARY FUNCTION IN PATIENTS WITH CEREBROVASCULAR DISEASE (STROKE).
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Biomedical Research; Blood; Cerebrovascu | 1964 |
[ADRENOCORTICAL AND PITUITARY FUNCTION FOLLOWING PROTRACTED PREDNISOLONE TREATMENT].
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Biomedical Research; | 1964 |
METHOPYRAPONE TESTS IN HYPOTHALAMIC-PITUITARY DISEASE.
Topics: Adrenocorticotropic Hormone; Brain Diseases; Brain Neoplasms; Diagnosis; Humans; Hypothalamic Diseas | 1964 |
[PITUITARY AND ADRENAL RESERVE FOLLOWING PROLONGED ADRENOCORTICAL THERAPY. PRELIMINARY COMMUNICATION].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Co | 1964 |
[STUDY ON THE ADRENOCORTICOTROPHIC RESERVE OF THE PITUITARY USING SU-4885 IN PATIENTS TREATED WITH CORTICOIDS].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Drug Therapy; Ketones; Metyrapone; Mineralocor | 1964 |
PITUITARY-ADRENAL FUNCTION DURING ACUTE PROCHLORPERAZINE ADMINISTRATION IN THE DOG.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Blood; Dogs; Hypophysectomy; | 1964 |
[STUDIES ON THE DIAGNOSTIC USE OF METOPIRONE (11-BETA-HYDROXYLASE INHIBITOR) IN DISEASES OF THE PITUITARY AND ADRENAL CORTEX].
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Blo | 1964 |
USE OF METHOPYRAPONE (SU-4885) IN THE STUDY OF PITUITARY-ADRENAL RESPONSE IN PATIENTS UNDER CORTICOSTEROID TREATMENT.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Cus | 1965 |
A STUDY OF PITUITARY FUNCTION AFTER INTRASELLAR IMPLANTATION OF 90YTTRIUM.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Basal Metabolism; Breast Neoplasms; Cushing | 1965 |
[The metopirone test in the diagnosis of diseases of the pituitary and adrenal cortex].
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Humans; Metyrapone; Pituitary Diseases; Pituitary Gland; Py | 1962 |
[Pituitary reactions to adrenalectomy for Cushing's syndrome and to the administration of SU 4885].
Topics: Adrenalectomy; Cushing Syndrome; Humans; Metyrapone; Pituitary Diseases; Pituitary Gland; Pyridines | 1961 |
Pituitary carcinoma mimics the ectopic adrenocorticotropin syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Dexamethasone; Diagnosis, D | 1980 |
The short metyrapone test: comparison of the plasma ACTH response to metyrapone with the cortisol response to insulin-induced hypoglycaemia in patients with pituitary disease.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Blood Glucose; Female; Humans; Hydrocortisone; Insulin; Ma | 1981 |
Melatonin and corticosteroid response to metyrapone in patients with pituitary disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Female; Humans; Hydrocortisone; M | 1982 |
The value of beta-lipotrophin measurement during the short metyrapone test in patients with pituitary diseases and in Cushing's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; beta-Lipotropin; Cortodoxone; Cushing Syndrome; Female; Humans; | 1984 |
Clinical evaluation of the liquid-chromatographic determination of urinary free cortisol.
Topics: Adolescent; Adrenal Gland Diseases; Adult; Age Factors; Chromatography, High Pressure Liquid; Dexame | 1983 |
The role of the low dose (1 microgram) adrenocorticotropin test in the evaluation of patients with pituitary diseases.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Femal | 1995 |
Pituitary function tests: comparison of ACTH and 11-deoxy-cortisol responses in the metyrapone test and with the insulin hypoglycemia test.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aged, 80 and over; Blood Glucose; Cortodoxone; Female; Hum | 1994 |
The assessment of the functional capacity of the hypothalamic-pituitary-adrenal axis by measurement of basal plasma and urinary cortisol in comparison with insulin-induced hypoglycaemia and metyrapone tests.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Evaluation Studies as Topic; Female; Humans; H | 1993 |
Comparison of low and high dose corticotropin stimulation tests in patients with pituitary disease.
Topics: Adult; Aged; Aged, 80 and over; Corticotropin-Releasing Hormone; Cosyntropin; Female; Humans; Hydroc | 1998 |
The low dose ACTH stimulation test is less sensitive than the overnight metyrapone test for the diagnosis of secondary hypoadrenalism.
Topics: Adult; Case-Control Studies; Cortodoxone; Cosyntropin; Female; Humans; Hydrocortisone; Male; Metyrap | 2000 |
[Diagnosis of growth hormone and ACTH deficiency in adults].
Topics: Adrenocorticotropic Hormone; Adult; Glucagon; Growth Hormone; Humans; Insulin; Metyrapone; Pituitary | 1975 |
[Diagnosis of growth hormone and ACTH deficiency in children].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Child; Glucocorticoids; Growth Hormone; Humans; Insu | 1975 |
[Experimental study of ACTH radioimmunoassay and its clinical application].
Topics: Adrenocorticotropic Hormone; Humans; Metyrapone; Pituitary Diseases; Radioimmunoassay | 1975 |
Radioimmunoassay of serum deoxycorticosterone: normal values and changes of serum deoxycorticosterone after adrenal stimulation.
Topics: Acromegaly; Addison Disease; Adrenocorticotropic Hormone; Adult; Chromatography, Paper; Desoxycortic | 1975 |
[Effects of various drugs on human serum ACTH secretion].
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Bromocriptine; Dexamethasone; Humans; Hydrocort | 1976 |
[Plasma concentrations of metopirone after oral administration in the child].
Topics: Administration, Oral; Adrenal Gland Diseases; Child; Humans; Metyrapone; Pituitary Diseases | 1976 |
[Interpretation of the metopirone--midnight-short-test by means of simultaneous determination and evaluation of the increase of 11-deoxycortisol and decrease of plasma 11-hydroxycorticosteroids].
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Cortodoxone; Humans; H | 1975 |
Assessment of hypothalamic-pituitary-adrenal (HPA) axis dysfunction: comparison of ACTH stimulation, insulin-hypoglycemia and metyrapone.
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Aldosteron | 1988 |
Immunoreactive corticotropin-releasing factor in human plasma.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Chromatography, High Pressure Liquid; Co | 1985 |
Usefulness of plasma pregnenolone sulfate in testing pituitary-adrenal function in children.
Topics: Adolescent; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aging; Child | 1986 |
Is the ovine CRF test an aid in the evaluation of patients with secondary adrenal insufficiency?
Topics: Adolescent; Adrenal Insufficiency; Adult; Aged; Corticotropin-Releasing Hormone; Female; Hormones; H | 1988 |
Immunoreactive corticotropin-releasing hormone present in human plasma may be derived from both hypothalamic and extrahypothalamic sources.
Topics: Adolescent; Adult; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liqu | 1987 |
Comparison of insulin hypoglycemia and short metyrapone tests in patients with pituitary disease.
Topics: Blood Glucose; Cortodoxone; Female; Humans; Hydrocortisone; Hypothalamic Diseases; Insulin; Male; Me | 1985 |
The primary empty sella: clinical and radiographic characteristics and endocrine function.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Aged; Cholesterol; Female; Gonadotrop | 1973 |
"Selective" pituitary insufficiency secondary to busulfan.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged | 1967 |
Coexisting anterior pituitary and neurohypophyseal insufficiency. A syndrome with diagnostic implication.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Biopsy; | 1969 |
Evaluation of ACTH reserve in pituitary-hypothalamic disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Brain Diseases; Child, Preschool; Female; Humans; Hy | 1966 |
Medical grand rounds from the University of Alabama Medical Center.
Topics: Adrenocorticotropic Hormone; Adult; Drinking; Humans; Male; Metyrapone; Pituitary Diseases; Pituitar | 1967 |
[Clinical studies on the adrenocorticotropic hormone. II. Studies on the mechanism of pituitary corticotropin secretion with synthetic lysine vasopressin].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Brain Neoplasms; Ci | 1968 |
[Anterior pituitary gland insufficiency in sarcoidosis].
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Cortisone; Female; Gluco | 1968 |
Studies o the levels of 17 hydroxy-corticoids in 24-hour specimens of urine from five quadriplegic patients and two paraplegic patients admitted to the Royal North Shore Hospital, Sydney.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Female; H | 1968 |
[Clinical studies on the stimulation and suppression of the pituitary-adrenocortical system. 3. Studies on the pituitary adrenocortical suppression after long-term glucocorticoid treatment].
Topics: 17-Hydroxycorticosteroids; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Arthriti | 1968 |
Studies of metyrapone responses in patients with pituitary disease.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Horm | 1969 |
[Diagnostic method and its clinical usefulness in hypothalamo-hypophyseo-adrenal insufficiency in children].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Child; Ch | 1969 |
Single-dose metyrapone test.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Humans; Hydrocortisone; Methods; Metyrapone; | 1970 |
The plasma 11-hydroxycorticosteroids responseto insulin-induced hypoglycaemia in children and adolescents.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood G | 1969 |
Vasopressin in the diagnostic evaluation of pituitary and hypothalamic function.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged | 1971 |
[Radioimmunoassay of ACTH].
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Humans; Immune Sera; Iodine Isotopes; Methods; | 1971 |
Simplified assessment of pituitary-adrenal reserve. Measurement of serum 11-deoxycortisol and cortisol after metyrapone.
Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Biotransformation; Child; Child, P | 1971 |
[Effects of lysine vasopressin on anterior pituitary secretions].
Topics: Adrenocorticotropic Hormone; Adult; Female; Fluorometry; Growth Hormone; Humans; Hydrocortisone; Lys | 1972 |
Urinary steroid dynamics after a single dose of metyrapone.
Topics: 17-Ketosteroids; Administration, Oral; Adolescent; Adrenocorticotropic Hormone; Adult; Child; Child, | 1974 |
Cushing's syndrome. An evaluation of the clinical usefulness of urinary free cortisol and other urinary steroid measurements in diagnosis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adult; Blood Proteins; Child; Creatinine | 1973 |
[Current aspects of the metopirone (SU-4885) test].
Topics: Administration, Oral; Humans; Injections, Intravenous; Metyrapone; Pituitary Diseases; Pituitary Neo | 1973 |
Tests of hypothalamic-pituitary-adrenal function in man.
Topics: Acromegaly; Adrenal Glands; Adult; Aged; Cushing Syndrome; Female; Fever; Glucocorticoids; Growth Ho | 1969 |
Use of lysin-vasopressin in the differential diagnosis of cushing's syndrome.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Diagnosis, Differential; Female; Hu | 1970 |
Hyperresponsiveness to metyrapone.
Topics: Adrenal Cortex Hormones; Anorexia Nervosa; Diabetes Mellitus; Growth; Growth Disorders; Humans; Hypo | 1967 |
[Urinary elimination of 17-hydroxycorticoids in patients with pituitary pathology during the administration of a bacterial pyrogen].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Female; Humans; Male; Metyrapone; Middle Aged; Pituita | 1968 |