metyrapone has been researched along with Pheochromocytoma in 15 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Saishouji, F | 1 |
| Maeda, S | 1 |
| Hamada, H | 1 |
| Kimura, N | 1 |
| Tamanoi, A | 1 |
| Nishida, S | 1 |
| Sakaguchi, M | 1 |
| Igata, M | 1 |
| Yokoo, K | 1 |
| Kawakami, F | 1 |
| Araki, E | 1 |
| Kondo, T | 1 |
| Inoue, M | 1 |
| Okamura, K | 1 |
| Kitaoka, C | 1 |
| Kinoshita, F | 1 |
| Namitome, R | 1 |
| Nakamura, U | 1 |
| Shiota, M | 1 |
| Goto, K | 1 |
| Ohtsubo, T | 1 |
| Matsumura, K | 1 |
| Oda, Y | 1 |
| Eto, M | 1 |
| Kitazono, T | 1 |
| Cohade, C | 1 |
| Broussaud, S | 1 |
| Louiset, E | 1 |
| Bennet, A | 1 |
| Huyghe, E | 1 |
| Caron, P | 1 |
| Shigekawa, T | 1 |
| Sato, T | 1 |
| Mizobuchi, S | 1 |
| Nakatsuka, H | 1 |
| Yokoyama, M | 1 |
| Morita, K | 1 |
| White, A | 1 |
| Ray, DW | 1 |
| Talbot, A | 1 |
| Abraham, P | 1 |
| Thody, AJ | 1 |
| Bevan, JS | 1 |
| Besser, GM | 1 |
| Jeffcoate, WJ | 1 |
| Beierwaltes, WH | 1 |
| Wieland, DM | 1 |
| Mosley, ST | 1 |
| Swanson, DP | 1 |
| Sarkar, SD | 1 |
| Freitas, JE | 1 |
| Thrall, JH | 1 |
| Herwig, KR | 1 |
| Carpenter, PC | 1 |
| Materazzi, F | 1 |
| Donahower, GF | 1 |
| Schumacher, OP | 1 |
| Hazard, JB | 1 |
| Berson, SA | 1 |
| Yalow, RS | 1 |
| Miura, K | 1 |
| Miura, S | 1 |
| Schein, PS | 1 |
| Torikai, T | 1 |
| Tada, T | 1 |
5 reviews available for metyrapone and Pheochromocytoma
| Article | Year |
|---|---|
Ectopic Cushing's syndrome due to a pheochromocytoma: a new case in the post-partum and review of literature.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Female; Humans; Insulin; Metyrapone | 2009 |
Cushing's syndrome: update of diagnosis and management.
Topics: Adenoma; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushin | 1986 |
[New endocrine disorders attracting current interest--adrenal system].
Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Ho | 1969 |
Chemotherapeutic management of the hormone-secreting endocrine malignancies.
Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Ant | 1972 |
[Aspect of hormones and hypertension].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol | 1969 |
10 other studies available for metyrapone and Pheochromocytoma
| Article | Year |
|---|---|
Ectopic ACTH-producing neuroendocrine tumor occurring with large recurrent metastatic pheochromocytoma: a case report.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aged, 80 and over; Cat | 2022 |
Metyrapone-responsive ectopic ACTH-secreting pheochromocytoma with a vicious cycle via a glucocorticoid-driven positive-feedback mechanism.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Antimetabolites; Feedback, Physiological; Gluc | 2018 |
[Perioperative treatment of a patient with ectopic ACTH-producing pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Anesthesia, Epid | 2007 |
Cushing's syndrome due to phaeochromocytoma secreting the precursors of adrenocorticotropin.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; alpha-MSH; Anti-Inflamma | 2000 |
Endocrine and metabolic diseases. Adrenal diseases.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici | 1976 |
Imaging the adrenal glands with radiolabeled inhibitors of enzymes: concise communication.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Animals; Breast Neoplasms; Dogs; Enzyme Inhibitors; Humans; | 1978 |
[Reichstein's S substance in humans].
Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; A | 1966 |
Medullary carcinoma of the thyroid--a cause of Cushing's syndrome: report of two cases.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Carci | 1968 |
Radioimmunoassay of ACTH in plasma.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Con | 1968 |
[Clinical studies on urinary 17-ketogenic steroid fractions. 3. SU-4885 test in normal subjects and the patients with various endocrine disorders].
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland N | 1968 |