metyrapone has been researched along with Neoplasms in 12 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Imaging tests by CT/MRI identified the tumors in 8 of 16 (50%), in 4 of 11 (36%) and 4 of 6 (66." | 1.36 | Clinical features and management of ectopic ACTH syndrome at a single institute in Japan. ( Doi, M; Hirata, Y; Izumiyama, H; Sugiyama, T; Yoshimoto, T, 2010) |
| "The sensitivity of tumors to cyclophosphamide (CPA) and other anticancer prodrugs can be substantially enhanced by transduction of tumors with a prodrug-activating mammalian cytochrome P450 (CYP) enzyme in combination with the flavoenzyme P450 reductase." | 1.31 | Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors. ( Huang, Z; Waxman, DJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doi, M | 1 |
| Sugiyama, T | 1 |
| Izumiyama, H | 1 |
| Yoshimoto, T | 1 |
| Hirata, Y | 1 |
| RIVADENEYRA, J | 1 |
| MAGGIOLO, J | 1 |
| CASTIGLIONI, CA | 1 |
| OLIVIERI, E | 1 |
| SOBOTA, JT | 1 |
| REED, RJ | 1 |
| WEST, CD | 1 |
| KUMAGAI, LF | 1 |
| SIMONS, EL | 1 |
| DOMINGUEZ, OB | 1 |
| BERLINER, DL | 1 |
| KRIEGER, DT | 1 |
| KOLODNY, H | 1 |
| KRIEGER, HP | 1 |
| BLEASEL, K | 1 |
| LAZARUS, L | 1 |
| Phlipponneau, M | 1 |
| Lenne, F | 1 |
| Proeschel, MF | 1 |
| Girard, F | 1 |
| Luton, JP | 1 |
| Bertagna, X | 1 |
| Huang, Z | 1 |
| Waxman, DJ | 1 |
| Stupfel, M | 1 |
| Abe, K | 1 |
| Gassel, WD | 1 |
| Gerdes, H | 1 |
| Littmann, KP | 1 |
12 other studies available for metyrapone and Neoplasms
| Article | Year |
|---|---|
Clinical features and management of ectopic ACTH syndrome at a single institute in Japan.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Aged; Corticotropin-Releasing Hormone; D | 2010 |
[INVESTIGATION OF THE BIOLOGICAL ACTIVITIES OF TRIAMCINOLONE DIACETATE IN PATIENTS WITH ADRENAL INSUFFICIENCY].
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenalectomy; Aldosterone; Blood; Blood Pressure; B | 1964 |
[EXPLORATION OF THE ACTH HYPOPHYSEAL RESERVE WITH METOPIRONE IN DIFFERENT ENDOCRINOPATHIES].
Topics: 17-Ketosteroids; Acromegaly; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Clinical Lab | 1963 |
MULTIPLE BRONCHIAL ADENOMAS, CUSHING'S SYNDROME AND HYPOKALEMIC ALKALOSIS. REPORT OF A CASE.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Alk | 1964 |
ADRENOCORTICAL CARCINOMA WITH FEMINIZATION AND HYPERTENSION ASSOCIATED WITH A DEFECT IN 11-BETA-HYDROXYLATION.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acne Vulgaris; Adrenal Cortex Hormones; Adrenal Gland Ne | 1964 |
METHOPYRAPONE TESTS IN HYPOTHALAMIC-PITUITARY DISEASE.
Topics: Adrenocorticotropic Hormone; Brain Diseases; Brain Neoplasms; Diagnosis; Humans; Hypothalamic Diseas | 1964 |
CRYOGENIC HYPOPHYSECTOMY.
Topics: Acromegaly; Betamethasone; Breast Neoplasms; Cryosurgery; Diabetic Retinopathy; Drug Therapy; Humans | 1965 |
Plasma immunoreactive joining peptide in man: a new marker of proopiomelanocortin processing and corticotroph function.
Topics: Adrenocorticotropic Hormone; Adult; beta-Lipotropin; Chromatography, Gel; Circadian Rhythm; Dexameth | 1993 |
Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors.
Topics: Animals; Antineoplastic Agents, Alkylating; Body Weight; Combined Modality Therapy; Cyclophosphamide | 2001 |
Biorhythms in toxicology and pharmacology. I. Generalities, ultradian and circadian biorhythms.
Topics: Adrenocorticotropic Hormone; Animals; Bacteria; Biological Clocks; Circadian Rhythm; Dexamethasone; | 1975 |
[Correlation of ACTH and MSH in man].
Topics: Addison Disease; Adrenocorticotropic Hormone; Cross Reactions; Cushing Syndrome; Hormones, Ectopic; | 1970 |
[Case report on a female patient with 17- -hydroxylase deficiency].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androgen-Insensitivity Syndrome; Corticosteron | 1971 |