metyrapone has been researched along with Neoplasm Metastasis in 16 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preoperative metyrapone treatment, which suppresses hypersecretion of endogenous glucocorticoids as a result of operation, modulates the enhancement of cancer metastases and may be an effective treatment." | 3.70 | Usefulness of metyrapone treatment to suppress cancer metastasis facilitated by surgical stress. ( Deguchi, M; Isobe, Y; Matsukawa, S; Nakagawara, G; Yamaguchi, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (87.50) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| RIVADENEYRA, J | 1 |
| COLE, VW | 1 |
| MANNHEIMER, IH | 1 |
| CRANE, MG | 1 |
| HARRIS, JJ | 1 |
| HERBER, R | 1 |
| Freeman, DA | 1 |
| Deguchi, M | 1 |
| Isobe, Y | 1 |
| Matsukawa, S | 1 |
| Yamaguchi, A | 1 |
| Nakagawara, G | 1 |
| Spence, RW | 1 |
| Burns-Cox, CJ | 1 |
| Sugawara, M | 1 |
| Hagen, GA | 1 |
| McElduff, A | 1 |
| Clifton-Bligh, P | 1 |
| Posen, S | 1 |
| Carey, RM | 1 |
| Orth, DN | 1 |
| Hartmann, WH | 1 |
| Landon, J | 1 |
| James, VH | 1 |
| Peart, WS | 1 |
| Coll, R | 1 |
| Horner, I | 1 |
| Kraiem, Z | 1 |
| Gafni, J | 1 |
| Morimoto, Y | 1 |
| Hiwada, K | 1 |
| Nanahoshi, M | 1 |
| Yano, S | 1 |
| Kumagai, A | 1 |
| Yamamura, Y | 1 |
| Koto, K | 1 |
| Uda, H | 1 |
| Okano, K | 1 |
| Yamane, G | 1 |
| Upton, GV | 1 |
| Amatruda, TT | 1 |
| Schein, PS | 1 |
| Newmark, SR | 1 |
| Dluhy, RG | 1 |
| Bennett, AH | 1 |
| Belchetz, PE | 1 |
| Brown, CL | 1 |
| Makin, HL | 1 |
| Trafford, DJ | 1 |
| Mason, AS | 1 |
| Bloom, SR | 1 |
| Ratcliffe, JG | 1 |
1 review available for metyrapone and Neoplasm Metastasis
| Article | Year |
|---|---|
Chemotherapeutic management of the hormone-secreting endocrine malignancies.
Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Ant | 1972 |
15 other studies available for metyrapone and Neoplasm Metastasis
| Article | Year |
|---|---|
[INVESTIGATION OF THE BIOLOGICAL ACTIVITIES OF TRIAMCINOLONE DIACETATE IN PATIENTS WITH ADRENAL INSUFFICIENCY].
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenalectomy; Aldosterone; Blood; Blood Pressure; B | 1964 |
URINARY PORTER-SILBER CHROMOGENS FOLLOWING INTRAVENOUS METHOPYRAPONE AND ACTH IN PATIENTS WITH BREAST CANCER.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Breast Neoplasms; Drug Therapy; Geriatrics; | 1965 |
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL CARCINOMA.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Alkalosis; Blood; Drug Therapy; Hyperaldosteronism | 1965 |
Adrenal carcinoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dia | 1994 |
Usefulness of metyrapone treatment to suppress cancer metastasis facilitated by surgical stress.
Topics: Adrenalectomy; Animals; Apoptosis; Corticosterone; Female; Leukocyte Count; Lung Neoplasms; Lymphocy | 1998 |
ACTH-secreting 'apudoma' of gallbladder.
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Adult; Autopsy; Cushing Syndrome; Dexamethasone; Diagno | 1975 |
Ectopic ACTH syndrome due to salivary gland adenoid cystic carcinoma.
Topics: Adrenocorticotropic Hormone; Aged; Autopsy; Carcinoma, Adenoid Cystic; Cushing Syndrome; Female; Hor | 1977 |
Metastatic medullary carcinoma of the thyroid complicated by Cushing's syndrome.
Topics: Adult; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dexamethasone; Drug Therapy, Combination; Hum | 1979 |
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon | 1973 |
Cushing's syndrome associated with a "corticotrophin"-producing bronchial neoplasm neoplasm (results of corticotrophin assays and of pituitary-adrenal function tests).
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adrenocorticotropi | 1967 |
Successful metyrapone therapy of the ectopic ACTH syndrome.
Topics: Adolescent; Adrenocorticotropic Hormone; Biopsy; Carcinoma; Cushing Syndrome; Cyclophosphamide; Horm | 1968 |
Cushing's syndrome caused by malignant tumor in the scrotum: clinical, pathologic and biochemical studies.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Rest Tumor; Adrenocorticotropic Hormone; Androst | 1971 |
Evidence for the presence of tumor peptides with corticotropin-releasing-factor-like activity in the ectopic ACTH syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Amino Acids; Animals; Biolo | 1971 |
Ectopic adrenocorticotropin syndrome with prostatic carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Gluco | 1973 |
ACTH, glucagon and gastrin production by a pancreatic islet cell carcinoma and its treatment.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Gastrins; Glucagon; Horm | 1973 |