Page last updated: 2024-10-31

metyrapone and Neoplasm Metastasis

metyrapone has been researched along with Neoplasm Metastasis in 16 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Preoperative metyrapone treatment, which suppresses hypersecretion of endogenous glucocorticoids as a result of operation, modulates the enhancement of cancer metastases and may be an effective treatment."3.70Usefulness of metyrapone treatment to suppress cancer metastasis facilitated by surgical stress. ( Deguchi, M; Isobe, Y; Matsukawa, S; Nakagawara, G; Yamaguchi, A, 1998)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's2 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RIVADENEYRA, J1
COLE, VW1
MANNHEIMER, IH1
CRANE, MG1
HARRIS, JJ1
HERBER, R1
Freeman, DA1
Deguchi, M1
Isobe, Y1
Matsukawa, S1
Yamaguchi, A1
Nakagawara, G1
Spence, RW1
Burns-Cox, CJ1
Sugawara, M1
Hagen, GA1
McElduff, A1
Clifton-Bligh, P1
Posen, S1
Carey, RM1
Orth, DN1
Hartmann, WH1
Landon, J1
James, VH1
Peart, WS1
Coll, R1
Horner, I1
Kraiem, Z1
Gafni, J1
Morimoto, Y1
Hiwada, K1
Nanahoshi, M1
Yano, S1
Kumagai, A1
Yamamura, Y1
Koto, K1
Uda, H1
Okano, K1
Yamane, G1
Upton, GV1
Amatruda, TT1
Schein, PS1
Newmark, SR1
Dluhy, RG1
Bennett, AH1
Belchetz, PE1
Brown, CL1
Makin, HL1
Trafford, DJ1
Mason, AS1
Bloom, SR1
Ratcliffe, JG1

Reviews

1 review available for metyrapone and Neoplasm Metastasis

ArticleYear
Chemotherapeutic management of the hormone-secreting endocrine malignancies.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Ant

1972

Other Studies

15 other studies available for metyrapone and Neoplasm Metastasis

ArticleYear
[INVESTIGATION OF THE BIOLOGICAL ACTIVITIES OF TRIAMCINOLONE DIACETATE IN PATIENTS WITH ADRENAL INSUFFICIENCY].
    Revista medica del Hospital General, 1964, Volume: 27

    Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenalectomy; Aldosterone; Blood; Blood Pressure; B

1964
URINARY PORTER-SILBER CHROMOGENS FOLLOWING INTRAVENOUS METHOPYRAPONE AND ACTH IN PATIENTS WITH BREAST CANCER.
    Cancer, 1965, Volume: 18

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Breast Neoplasms; Drug Therapy; Geriatrics;

1965
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL CARCINOMA.
    Annals of internal medicine, 1965, Volume: 63

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Alkalosis; Blood; Drug Therapy; Hyperaldosteronism

1965
Adrenal carcinoma.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dia

1994
Usefulness of metyrapone treatment to suppress cancer metastasis facilitated by surgical stress.
    Surgery, 1998, Volume: 123, Issue:4

    Topics: Adrenalectomy; Animals; Apoptosis; Corticosterone; Female; Leukocyte Count; Lung Neoplasms; Lymphocy

1998
ACTH-secreting 'apudoma' of gallbladder.
    Gut, 1975, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Adult; Autopsy; Cushing Syndrome; Dexamethasone; Diagno

1975
Ectopic ACTH syndrome due to salivary gland adenoid cystic carcinoma.
    Archives of internal medicine, 1977, Volume: 137, Issue:1

    Topics: Adrenocorticotropic Hormone; Aged; Autopsy; Carcinoma, Adenoid Cystic; Cushing Syndrome; Female; Hor

1977
Metastatic medullary carcinoma of the thyroid complicated by Cushing's syndrome.
    The Medical journal of Australia, 1979, Mar-10, Volume: 1, Issue:5

    Topics: Adult; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dexamethasone; Drug Therapy, Combination; Hum

1979
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon

1973
Cushing's syndrome associated with a "corticotrophin"-producing bronchial neoplasm neoplasm (results of corticotrophin assays and of pituitary-adrenal function tests).
    Acta endocrinologica, 1967, Volume: 56, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adrenocorticotropi

1967
Successful metyrapone therapy of the ectopic ACTH syndrome.
    Archives of internal medicine, 1968, Volume: 121, Issue:6

    Topics: Adolescent; Adrenocorticotropic Hormone; Biopsy; Carcinoma; Cushing Syndrome; Cyclophosphamide; Horm

1968
Cushing's syndrome caused by malignant tumor in the scrotum: clinical, pathologic and biochemical studies.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 32, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Rest Tumor; Adrenocorticotropic Hormone; Androst

1971
Evidence for the presence of tumor peptides with corticotropin-releasing-factor-like activity in the ectopic ACTH syndrome.
    The New England journal of medicine, 1971, Aug-19, Volume: 285, Issue:8

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Amino Acids; Animals; Biolo

1971
Ectopic adrenocorticotropin syndrome with prostatic carcinoma.
    Urology, 1973, Volume: 2, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenocorticotropic Hormone; Blood Gluco

1973
ACTH, glucagon and gastrin production by a pancreatic islet cell carcinoma and its treatment.
    Clinical endocrinology, 1973, Volume: 2, Issue:4

    Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Gastrins; Glucagon; Horm

1973