Page last updated: 2024-10-31

metyrapone and Myasthenia Gravis

metyrapone has been researched along with Myasthenia Gravis in 4 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KLEIN, JJ1
OSSERMAN, KE1
Grob, D1
Namba, T1
Cape, CA2
Arbona, NJ2
Patterson, SM1

Other Studies

4 other studies available for metyrapone and Myasthenia Gravis

ArticleYear
STUDIES IN MYASTHENIA GRAVIS. PITUITARY-ADRENAL FUNCTION.
    The New England journal of medicine, 1964, Jul-23, Volume: 271

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Biomedical Re

1964
Corticotropin in generalized myasthenia gravis. Effect of short, intensive courses.
    JAMA, 1966, Nov-14, Volume: 198, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Female; Humans; Injections, Intramuscular; Injections, Intraveno

1966
Correlation of the clinical response to ACTH treatment with the endocrine status in myasthenia gravis.
    Southern medical journal, 1973, Volume: 66, Issue:9

    Topics: Adrenocorticotropic Hormone; Dexamethasone; Eye Diseases; Humans; Metyrapone; Myasthenia Gravis; Pit

1973
Endogenous ACTH induced remission in myasthenia gravis.
    Bulletin of the Los Angeles neurological societies, 1973, Volume: 38, Issue:4

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Dexamethasone; Humans; Male; Metyrapone; Middle Aged; M

1973