metyrapone has been researched along with Muscle Contraction in 3 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metyrapone was also a relaxant agent, and its action was greater at low than at high PO2." | 1.27 | Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus. ( Coceani, F; Hamilton, NC; Labuc, J; Olley, PM, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singer, HA | 1 |
| Saye, JA | 1 |
| Peach, MJ | 1 |
| Coceani, F | 1 |
| Hamilton, NC | 1 |
| Labuc, J | 1 |
| Olley, PM | 1 |
| Parnham, MJ | 1 |
3 other studies available for metyrapone and Muscle Contraction
| Article | Year |
|---|---|
Effects of cytochrome P-450 inhibitors on endothelium-dependent relaxation in rabbit aorta.
Topics: Animals; Aorta; Calcium; Cytochrome P-450 Enzyme Inhibitors; Endothelium; Ionophores; Male; Methacho | 1984 |
Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Female; Guinea Pigs; In | 1984 |
Effects of metyrapone on rat uterine prostaglandin release and on spontaneous smooth muscle activity in vitro [proceedings].
Topics: Animals; Female; In Vitro Techniques; Metyrapone; Muscle Contraction; Muscle, Smooth; Prostaglandins | 1976 |