metyrapone has been researched along with Lung Neoplasms in 12 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preoperative metyrapone treatment, which suppresses hypersecretion of endogenous glucocorticoids as a result of operation, modulates the enhancement of cancer metastases and may be an effective treatment." | 3.70 | Usefulness of metyrapone treatment to suppress cancer metastasis facilitated by surgical stress. ( Deguchi, M; Isobe, Y; Matsukawa, S; Nakagawara, G; Yamaguchi, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwayama, H | 1 |
| Hirase, S | 1 |
| Nomura, Y | 1 |
| Ito, T | 1 |
| Morita, H | 1 |
| Otake, K | 1 |
| Okumura, A | 1 |
| Takagi, J | 1 |
| Aziz, SI | 1 |
| Khattak, MA | 1 |
| Usmani, Z | 1 |
| Ladipeerla, N | 1 |
| Pittman, K | 1 |
| Suda, T | 1 |
| Tozawa, F | 1 |
| Dobashi, I | 1 |
| Horiba, N | 1 |
| Ohmori, N | 1 |
| Yamakado, M | 1 |
| Yamada, M | 1 |
| Demura, H | 1 |
| Deguchi, M | 1 |
| Isobe, Y | 1 |
| Matsukawa, S | 1 |
| Yamaguchi, A | 1 |
| Nakagawara, G | 1 |
| Koelmeyer, TD | 1 |
| Woods, WP | 1 |
| Wiedemann, E | 1 |
| Saito, T | 1 |
| Linfoot, JA | 1 |
| Li, CH | 1 |
| Dimopoulos, MA | 1 |
| Fernandez, JF | 1 |
| Samaan, NA | 1 |
| Holoye, PY | 1 |
| Vassilopoulou-Sellin, R | 1 |
| Steel, K | 1 |
| Baerg, RD | 1 |
| Adams, DO | 1 |
| Coll, R | 1 |
| Horner, I | 1 |
| Kraiem, Z | 1 |
| Gafni, J | 1 |
| Brun, J | 1 |
| Revol, A | 1 |
| Queneau, P | 1 |
| Sachs, BA | 1 |
| Becker, N | 1 |
| Bloomberg, AE | 1 |
| Grunwald, RP | 1 |
| Upton, GV | 1 |
| Amatruda, TT | 1 |
12 other studies available for metyrapone and Lung Neoplasms
| Article | Year |
|---|---|
Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Aged; Female; Humans; Hydrocortisone; Lung Neop | 2018 |
Metyrapone: a management option for ectopic ACTH syndrome in small cell lung cancer treated with intravenous etoposide.
Topics: ACTH Syndrome, Ectopic; Antineoplastic Agents, Phytogenic; Etoposide; Female; Humans; Infusions, Int | 2011 |
Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Arginine | 1993 |
Usefulness of metyrapone treatment to suppress cancer metastasis facilitated by surgical stress.
Topics: Adrenalectomy; Animals; Apoptosis; Corticosterone; Female; Leukocyte Count; Lung Neoplasms; Lymphocy | 1998 |
Carcinoma of the lung presenting as Cushing's syndrome.
Topics: Aminoglutethimide; Carcinoma, Bronchogenic; Cortisone; Cushing Syndrome; Cyclophosphamide; Diagnosis | 1977 |
Specific radioimmunoassay of human beta-endorphin in unextracted plasma.
Topics: Adenoma; Adrenal Gland Neoplasms; Carcinoma, Bronchogenic; Cushing Syndrome; Dexamethasone; Endorphi | 1979 |
Paraneoplastic Cushing's syndrome as an adverse prognostic factor in patients who die early with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cushing Syndrome; Female; Humans; Lung Ne | 1992 |
Cushing's syndrome in association with a carcinoid tumor of the lung.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Carcinoid Tumor; Cushing Sy | 1967 |
Successful metyrapone therapy of the ectopic ACTH syndrome.
Topics: Adolescent; Adrenocorticotropic Hormone; Biopsy; Carcinoma; Cushing Syndrome; Cyclophosphamide; Horm | 1968 |
[Broncho-pulmonary cancer with true or degraded hypercorticism].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon | 1969 |
"Cure" of ectopic ACTH syndrome secondary to adrenocarcinoma of the lung.
Topics: 17-Ketosteroids; Acid Phosphatase; Adenocarcinoma; Adrenocorticotropic Hormone; Cushing Syndrome; Cy | 1970 |
Evidence for the presence of tumor peptides with corticotropin-releasing-factor-like activity in the ectopic ACTH syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Amino Acids; Animals; Biolo | 1971 |