metyrapone has been researched along with Lung Injury, Acute in 1 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to determine the effects of previous administration of metyrapone (met) on the acute lung injury (ALI) induced by caecal ligation and puncture (CLP) and to explore met's relationship with endogenous glucocorticoids (GCs) as measured by inflammatory, oxidative and functional parameters." | 3.81 | Inhibition of endogenous glucocorticoid synthesis aggravates lung injury triggered by septic shock in rats. ( Incerpi, EK; Oliveira, LM; Pereira, EM; Soncini, R, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Incerpi, EK | 1 |
| Oliveira, LM | 1 |
| Pereira, EM | 1 |
| Soncini, R | 1 |
1 other study available for metyrapone and Lung Injury, Acute
| Article | Year |
|---|---|
Inhibition of endogenous glucocorticoid synthesis aggravates lung injury triggered by septic shock in rats.
Topics: Acute Lung Injury; Animals; Corticosterone; Disease Models, Animal; Down-Regulation; Enzyme Inhibito | 2015 |