metyrapone has been researched along with Kidney Diseases in 6 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As phenobarbital treatment in young rats enhanced the symptoms of nephrotoxicity and metyrapone treatment in adult rats decreased the symptoms of nephrotoxicity, age-dependent differences in chromate nephrotoxicity may be linked to an increase in the enzymatic reduction of Cr(VI) with age." | 1.28 | Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats. ( Appenroth, D; Bräunlich, H; Friese, KH; Gambaryan, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, Q | 1 |
| Yin, L | 1 |
| Hartmann, RW | 1 |
| Appenroth, D | 1 |
| Gambaryan, S | 1 |
| Friese, KH | 1 |
| Bräunlich, H | 1 |
| Brackett, NC | 1 |
| Koppel, M | 1 |
| Randall, RE | 1 |
| Nixon, WP | 1 |
| Tamura, M | 1 |
| Clary, JJ | 1 |
| Stokinger, HE | 1 |
| Dixit, VP | 1 |
6 other studies available for metyrapone and Kidney Diseases
| Article | Year |
|---|---|
Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases.
Topics: Aldosterone; Animals; Benzimidazoles; Cardiovascular Diseases; Cytochrome P-450 CYP11B2; Fadrozole; | 2014 |
Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats.
Topics: Aging; Animals; Chromates; Chromium; Cromolyn Sodium; Female; Kidney; Kidney Diseases; Kidney Tubule | 1990 |
Hyperplasia of the juxtaglomerular complex with secondary aldosteronism without hypertension (Bartter's syndrome).
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Ammonium Chloride; Angiotensin II; Bicarb | 1968 |
[Adrenal function in urological patients].
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adu | 1971 |
The mechanism of delayed biologic response following beryllium exposure.
Topics: Adrenal Insufficiency; Adrenalectomy; Animals; Beryllium; Body Weight; Bone and Bones; Chemical and | 1973 |
Histophysiological studies of the interrenal gland in Clarias batrachus Linn.
Topics: Animals; Atrophy; Cortisone; Fishes; Histocytochemistry; Hypophysectomy; Kidney; Kidney Diseases; Me | 1970 |