Page last updated: 2024-10-31

metyrapone and Infarction, Middle Cerebral Artery

metyrapone has been researched along with Infarction, Middle Cerebral Artery in 2 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
"Acute hyperglycemia was induced by IP injection of dextrose 30 minutes before ischemia."1.33Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation. ( Bargalló, N; Chamorro, A; Falcón, C; Martín, A; Planas, AM; Rojas, S, 2006)
"Adult male mice underwent middle cerebral artery occlusion (MCAO), and were recovered 7 days."1.33Role of IL-1 in poststroke depressive-like behavior in mice. ( Craft, TK; DeVries, AC, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martín, A1
Rojas, S1
Chamorro, A1
Falcón, C1
Bargalló, N1
Planas, AM1
Craft, TK1
DeVries, AC1

Other Studies

2 other studies available for metyrapone and Infarction, Middle Cerebral Artery

ArticleYear
Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation.
    Stroke, 2006, Volume: 37, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Disease Progression; Glycosylation; Hyperglycemia

2006
Role of IL-1 in poststroke depressive-like behavior in mice.
    Biological psychiatry, 2006, Oct-15, Volume: 60, Issue:8

    Topics: Animals; Antimetabolites; Depressive Disorder; Drinking Behavior; Glucocorticoids; Hormone Antagonis

2006