metyrapone has been researched along with Hypotension in 3 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the process of developing a model of Escherichia coli endotoxin-induced acute lung injury and shock in specific pathogen-free pigs, the effects of pretreatment with metyrapone (a cortisol-synthesis inhibitor) were examined." | 3.70 | Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock, and nitric oxide production. ( Alving, K; Bergman, D; Middelveld, RJ; Wanecek, M; Weitzberg, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stacpoole, PW | 1 |
| Interlandi, JW | 1 |
| Nicholson, WE | 1 |
| Rabin, D | 1 |
| Middelveld, RJ | 1 |
| Wanecek, M | 1 |
| Bergman, D | 1 |
| Weitzberg, E | 1 |
| Alving, K | 1 |
| Kley, HK | 1 |
| Krüskemper, HL | 1 |
3 other studies available for metyrapone and Hypotension
| Article | Year |
|---|---|
Isolated ACTH deficiency: a heterogeneous disorder. Critical review and report of four new cases.
Topics: 17-Hydroxycorticosteroids; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Blood Glucose; | 1982 |
Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock, and nitric oxide production.
Topics: Acid-Base Imbalance; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Disease Models, Anim | 1999 |
[Performance and interpretation of a shortened metyrapone test].
Topics: 11-Hydroxycorticosteroids; Acromegaly; Adolescent; Adult; Aged; Circadian Rhythm; Diabetes Mellitus; | 1972 |