metyrapone has been researched along with Hyperandrogenism in 1 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Hyperandrogenism: A condition caused by the excessive secretion of ANDROGENS from the ADRENAL CORTEX; the OVARIES; or the TESTES. The clinical significance in males is negligible. In women, the common manifestations are HIRSUTISM and VIRILISM as seen in patients with POLYCYSTIC OVARY SYNDROME and ADRENOCORTICAL HYPERFUNCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Symptoms of hyperandrogenism are common in patients with Cushing's disease (CD), yet they are not sufficiently explained by androgen concentrations." | 1.72 | 11-Oxygenated C19 steroids are the predominant androgens responsible for hyperandrogenemia in Cushing's disease. ( Adaway, JE; Auer, MK; Bidlingmaier, M; Braun, L; Hartmann, MF; Hawley, J; Keevil, B; Lottspeich, C; Nowotny, HF; Reincke, M; Reisch, N; Schilbach, K; Tschaidse, L; Vogel, F; Wudy, SA, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nowotny, HF | 1 |
| Braun, L | 1 |
| Vogel, F | 1 |
| Bidlingmaier, M | 1 |
| Reincke, M | 1 |
| Tschaidse, L | 1 |
| Auer, MK | 1 |
| Lottspeich, C | 1 |
| Wudy, SA | 1 |
| Hartmann, MF | 1 |
| Hawley, J | 1 |
| Adaway, JE | 1 |
| Keevil, B | 1 |
| Schilbach, K | 1 |
| Reisch, N | 1 |
1 other study available for metyrapone and Hyperandrogenism
| Article | Year |
|---|---|
11-Oxygenated C19 steroids are the predominant androgens responsible for hyperandrogenemia in Cushing's disease.
Topics: Adrenocorticotropic Hormone; Androgens; Androstenedione; Androsterone; Cortisone; Dehydroepiandroste | 2022 |