Page last updated: 2024-10-31

metyrapone and Glaucoma

metyrapone has been researched along with Glaucoma in 3 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"Domestic chicks reared under continuous dim light developed the eye enlargement and suppressed corneal growth characteristic of light-induced avian glaucoma (LIAG) and dim light buphthalmos (DLB)."3.67Light, experimental avian myopia and the role of the suprarenals. ( Lauber, JK; Oishi, T, 1986)
" This dosage resulted in partial adrenal suppression, manifested by reduced levels of plasma cortisol."1.26Topical corticosteroid therapy and pituitary-adrenal function. ( Becker, B; Krupin, T; Mandell, AI; Podos, SM, 1976)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krupin, T1
Mandell, AI1
Podos, SM1
Becker, B1
Oishi, T1
Lauber, JK1
Selchau, M1

Reviews

1 review available for metyrapone and Glaucoma

ArticleYear
[Diuretics. 47].
    Pharmazeutische Praxis, 1970, Volume: 9

    Topics: Antihypertensive Agents; Bendroflumethiazide; Chlorothiazide; Chlorthalidone; Clopamide; Dichlorphen

1970

Other Studies

2 other studies available for metyrapone and Glaucoma

ArticleYear
Topical corticosteroid therapy and pituitary-adrenal function.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:6

    Topics: Administration, Topical; Cortodoxone; Dexamethasone; Glaucoma; Humans; Hydrocortisone; Hypothalamus;

1976
Light, experimental avian myopia and the role of the suprarenals.
    Journal of ocular pharmacology, 1986,Spring, Volume: 2, Issue:2

    Topics: Adrenal Cortex; Animals; Chickens; Corticosterone; Eye; Glaucoma; Light; Metyrapone

1986