metyrapone has been researched along with Eosinophilia, Tropical in 4 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metyrapone significantly increased eosinophil infiltration (17." | 5.29 | Effect of dexamethasone and endogenous corticosterone on airway hyperresponsiveness and eosinophilia in the mouse. ( De Bie, JJ; Hessel, EM; Hofman, G; Nijkamp, FP; Van Ark, I; Van Esch, B; Van Oosterhout, AJ, 1996) |
| "Metyrapone (MET) was used to inhibit GC synthesis, and RU486 to block GC actions." | 1.40 | Essential roles of endogenous glucocorticoids and TNF/TNFR1 in promoting bone-marrow eosinopoiesis in ovalbumin-sensitized, airway-challenged mice. ( Almeida da Silva, CL; Gaspar-Elsas, MI; Lopes, RS; Luz, RA; Masid-de-Brito, D; Queto, T; Vieira, BM; Xavier-Elsas, P, 2014) |
| "Metyrapone treatment prolonged the acute release of histamine, and this was seen together with a prolonged acute bronchoconstrictor response." | 1.29 | Allergen-induced late-phase airways obstruction in the pig: mediator release and eosinophil recruitment. ( Alving, K; Fornhem, C; Kumlin, M; Lundberg, JM, 1995) |
| "Treatment with metyrapone significantly increased eosinophil infiltration (17." | 1.29 | Effect of dexamethasone and endogenous corticosterone on airway hyperresponsiveness and eosinophilia in the mouse. ( De Bie, JJ; Hessel, EM; Hofman, G; Nijkamp, FP; Van Ark, I; Van Esch, B; Van Oosterhout, AJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masid-de-Brito, D | 1 |
| Xavier-Elsas, P | 1 |
| Luz, RA | 1 |
| Queto, T | 1 |
| Almeida da Silva, CL | 1 |
| Lopes, RS | 1 |
| Vieira, BM | 1 |
| Gaspar-Elsas, MI | 1 |
| Georén, S | 1 |
| Ahnblad, P | 1 |
| Stjärne, P | 1 |
| Wikström, AC | 1 |
| Stierna, P | 1 |
| Fornhem, C | 1 |
| Kumlin, M | 1 |
| Lundberg, JM | 1 |
| Alving, K | 1 |
| De Bie, JJ | 1 |
| Hessel, EM | 1 |
| Van Ark, I | 1 |
| Van Esch, B | 1 |
| Hofman, G | 1 |
| Nijkamp, FP | 1 |
| Van Oosterhout, AJ | 1 |
4 other studies available for metyrapone and Eosinophilia, Tropical
| Article | Year |
|---|---|
Essential roles of endogenous glucocorticoids and TNF/TNFR1 in promoting bone-marrow eosinopoiesis in ovalbumin-sensitized, airway-challenged mice.
Topics: Animals; Bone Marrow; Corticosterone; Eosinophilia; Eosinophils; Female; Glucocorticoids; Inflammati | 2014 |
Significance of endogenous glucocorticoid sensitivity for airway eosinophilia in a murine model of allergy.
Topics: Administration, Intranasal; Airway Resistance; Animals; Asthma; Bone Marrow; Bronchi; Disease Models | 2005 |
Allergen-induced late-phase airways obstruction in the pig: mediator release and eosinophil recruitment.
Topics: Allergens; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstr | 1995 |
Effect of dexamethasone and endogenous corticosterone on airway hyperresponsiveness and eosinophilia in the mouse.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; | 1996 |